Results 81 to 90 of about 25,402 (289)

Snake venom toxins: Potential anticancer therapeutics

open access: yesJournal of Applied Toxicology, Volume 44, Issue 5, Page 666-685, May 2024.
Abstract Snake venom contains a cocktail of compounds dominated by proteins and peptides, which make up the toxin. The toxin components of snake venom attack several targets in the human body including the neuromuscular system, kidney and blood coagulation system and cause pathologies. As such, the venom toxins can be managed and used for the treatment
Benedict C. Offor, Lizelle A. Piater
wiley   +1 more source

Water Carcinogenicity and Prevalence of HPV Infection in Esophageal Cancer Patients in Huaihe River Basin, China

open access: yesGastroenterology Research and Practice, 2018
Objective. The incidence of the upper gastrointestinal tumor has increased rapidly during recent decades. The relationship between local water pollution and the tumor is still not much clear, so this study was conducted to further investigate the local ...
Maliha Ghaffar   +9 more
doaj   +1 more source

Effects of phenobarbital, dexamethasone, and 3-methylcholanthrene administration on the metabolism of 17 beta-estradiol by liver microsomes from female rats.

open access: yesEndocrinology, 1996
Female rats were treated with phenobarbital, dexamethasone, 3-methylcholanthrene, clofibrate, or isoniazid to induce different hepatic cytochromes P-450.
L. A. Suchar   +5 more
semanticscholar   +1 more source

Animals bearing malignant grafts reject normal grafts that express through gene transfer the same antigen. [PDF]

open access: yes, 1990
Breaking the state of immunological unresponsiveness of tumor-bearing individuals to cancer is a prerequisite for active or passive tumor-specific immunotherapy.
Koeppen, H   +5 more
core  

Nutritional Sources and Anticancer Potential of Phenethyl Isothiocyanate: Molecular Mechanisms and Therapeutic Insights

open access: yesMolecular Nutrition &Food Research, Volume 68, Issue 8, April 2024.
Phenethyl Isothiocyanate (PEITC) exhibits its anticancer potential by modulating key signaling pathways, enforcing cell cycle arrest, promoting apoptosis, and enhancing drug efficacy by overcoming multidrug resistance and influencing drug metabolism enzymes.
Shahira M. Ezzat   +11 more
wiley   +1 more source

UDP-glucuronyltransferase in perfused rat liver and in microsomes: influence of phenobarbital and 3-methylcholanthrene.

open access: yesEuropean Journal of Biochemistry, 1974
Liver microsomal UDP-glucuronyltransferase (1-naphthol as substrate) is activated about 10-fold by treatment of native microsomes in vitro with Triton X-100.
K. Bock, I. White
semanticscholar   +1 more source

In vitro studies on tumor-specific immunity by using C3H mammary cancer-A cells. I. Inhibitory effect of lymph-node cells from the tumor bearing isologous C3H mouse on the proliferation of the tumor cells [PDF]

open access: yes, 1966
As a link in the series of studies on tumor-specific immunity, in vitro inhibitory effect of sensitized isologous lymph-node cells on the proliferation of C3H mammary cancer was studied.
Satoh, Katuaki
core   +1 more source

Targets of tumor microenvironment for potential drug development

open access: yesMedComm – Oncology, Volume 3, Issue 1, March 2024.
Here we review the potential targets of drugs according to the components of the tumor microenvironment (TME), including immune cells, stromal cells, and extracellular matrix (ECM) proteins, and further classify the key genes based on whether they function in direct or indirect way, to provide a comprehensive view of the current landscape of cancer ...
Ling Zhang   +7 more
wiley   +1 more source

Inhibition of Methylcholanthrene-induced Carcinogenesis by an Interferon γ Receptor–dependent Foreign Body Reaction

open access: yesJournal of Experimental Medicine, 2002
The foreign body reaction is one of the oldest host defense mechanisms against tissue damage which involves inflammation, scarring, and encapsulation. The chemical carcinogen methylcholanthrene (MCA) induces fibrosarcoma and tissue damage in parallel at ...
Zhihai Qin   +3 more
semanticscholar   +1 more source

Update of the risk assessment of polybrominated diphenyl ethers (PBDEs) in food

open access: yesEFSA Journal, Volume 22, Issue 1, January 2024.
Abstract The European Commission asked EFSA to update its 2011 risk assessment on polybrominated diphenyl ethers (PBDEs) in food, focusing on 10 congeners: BDE‐28, ‐47, ‐49, ‐99, ‐100, ‐138, ‐153, ‐154, ‐183 and ‑209. The CONTAM Panel concluded that the neurodevelopmental effects on behaviour and reproductive/developmental effects are the critical ...
EFSA Panel on Contaminants in the Food Chain (CONTAM)   +26 more
wiley   +1 more source

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