Results 181 to 190 of about 2,824 (198)

Methyleugenol and oxidative metabolites induce DNA damage and interact with human topoisomerases

Archives of Toxicology, 2015
Methyleugenol is a substituted alkenylbenzene found in several herbs and spices. It is classified by the European Union's Scientific Committee on Food as a genotoxic carcinogen. We addressed the biological mechanism of the genotoxic properties of methyleugenol and its oxidative metabolites.
Groh, Isabel Anna Maria, Rudakovski, Olga, Gruendken, Malte, Schroeter, Anika, Marko, Doris, Esselen, Melanie   +5 more
openaire   +2 more sources

Methyleugenol reduces cerebral ischemic injury by suppression of oxidative injury and inflammation

Free Radical Research, 2010
The present study tested the cytoprotective effect of methyleugenol in an in vivo ischemia model (i.e. middle cerebral artery occlusion (MCAO) for 1.5 h and subsequent reperfusion for 24 h) and further investigated its mechanism of action in in vitro cerebral ischemic models.
Yoo Keum, Choi, Geum-Sil, Cho, Sunyoung, Hwang, Byung Woo, Kim, Ji H, Lim, Jae-Chul, Lee, Hyoung Chun, Kim, Won-Ki, Kim, Yeong Sik, Kim   +8 more
openaire   +2 more sources

Methyleugenol counteracts anorexigenic signals in association with GABAergic inhibition in the central amygdala

Neuropharmacology, 2018
Feeding can be inhibited by satiety, sickness, or food unpalatability. The central nucleus of the amygdala (CeA) has been considered the key region for processing multiple anorexigenic signals, although the detailed cellular and molecular mechanisms remain largely unclear. Here we identify that methyleugenol (ME), a novel agonist of A type ionotropic γ-
Tailin Zhu, Yuhua Yan, Shining Deng, Yan-Mei Liu, Hui-Ran Fan, Bingke Ma, Bo Meng, Bing Mei, Wei-Guang Li, Fei Li   +9 more
openaire   +2 more sources

Toxicokinetics of methyleugenol in F344 rats and B6C3F₁ mice.

Xenobiotica; the fate of foreign compounds in biological systems, 2013
1. Methyleugenol (MEG) has been used as a flavouring agent in food, as a fragrance in cosmetic products, and as an insect attractant. MEG was carcinogenic in both rats and mice following gavage administration. In this study we investigated plasma toxicokinetics of MEG in F344 rats and B6C3F₁ mice of both sexes following single gavage (37, 75, or 150 mg/
S Peter, Hong, Alfred F, Fuciarelli, Jerry D, Johnson, Steven W, Graves, Derrick J, Bates, Suramya, Waidyanatha, Cynthia S, Smith   +6 more
openaire   +1 more source

Reactions of tellurium tetrahalides with methyleugenol

Russian Journal of Organic Chemistry, 2015
M. V. Musalova, M. V. Musalov, S. I. Udalova, V. A. Potapov, S. V. Amosova   +4 more
openaire   +1 more source

Methyleugenol

2020
openaire   +1 more source

Toxicological properties of methyleugenol and methylisoeugenol metabolites

Toxicology Letters, 2012
Alexander Thomas Cartus, Kristin Herrmann, Isabel Groh, Lucas Willi Weishaupt, Karl-Heinz Merz, Wolfram Engst, Hansruedii Glatt, Melanie Esselen, Dieter Schrenk   +8 more
openaire   +1 more source

Methyleugenol in the Diet

2005
Kamal Abdo, Jerry Johnson
openaire   +1 more source

ChemInform Abstract: Electrosynthesis of γ‐Asarone (IV) from Methyleugenol (I).

ChemInform, 1990
R. R. VARGAS, V. L. PARDINI, H. VIERTLER
openaire   +1 more source

Methyleugenol.

Report on carcinogens : carcinogen profiles, 2012
openaire   +1 more source