Results 161 to 170 of about 1,735 (188)
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Suppression ofl-Histidine Decarboxylase mRNA Expression by Methyleugenol
Biochemical and Biophysical Research Communications, 1997We investigated the effect of methyleugenol on anaphylaxis. Methyleugenol completely inhibited systemic anaphylaxis induced by compound 48/80 in mice. Methyleugenol also inhibited local anaphylaxis activated by anti-dinitrophenyl (DNP) IgE. Moreover, methyleugenol dose-dependently inhibited histamine release in mast cells activated by compound 48/80 or
B K, Shin, E H, Lee, H M, Kim
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Reduction of Safrole and Methyleugenol in Asari radix et rhizoma by Decoction
Forschende Komplementärmedizin / Research in Complementary Medicine, 2009Asari radix et rhizoma (Xixin, Manchurian Wildginger, Asarum spp) is a herbal drug commonly used as an ingredient in traditional Chinese medicine (TCM). Many species of Asarum contain safrole and methyleugenol as the main components of their volatile oils.
Chen C, Spriano D, Lehmann T, Meier B
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Electrophysiological Characterization of Methyleugenol: A Novel Agonist of GABA(A) Receptors
ACS Chemical Neuroscience, 2014Methyleugenol (ME) is a natural constituent isolated from many plant essential oils having multiple biological effects including anticonvulsant and anesthetic activities, although the underlying mechanisms remain unclear. Here, we identify ME as a novel agonist of ionotropic γ-aminobutyric acid (GABA) receptors.
Jing, Ding +9 more
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Methyleugenol in Ocimum basilicum L. Cv. Genovese Gigante
Journal of Agricultural and Food Chemistry, 2000Ocimum basilicum cv. Genovese Gigante is the basil cultivar used the most in the production of a typical Italian sauce called pesto. The aromatic composition of plants at different growth stages was determined. Plants from different areas of northwestern Italy were analyzed at 4 and 6 weeks after sowing and showed methyleugenol and eugenol as the main ...
MIELE M. +3 more
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Relaxant and Antispasmodic Actions of Methyleugenol on Guinea-Pig Isolated Ileum
Planta Medica, 2000The effects of methyleugenol (ME) on guinea-pig isolated ileum were studied. ME reversibly relaxed basal tonus (EC50 of 52.2 +/- 18.3 microM), an action unaltered by 0.5 microM tetrodotoxin or 0.5 mM hexamethonium, and relaxed the ileum pre-contracted with 60 mM KCl.
C C, Lima +5 more
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Mechanistic Insight into Difference in Hepatotoxicity of Methyleugenol and Safrole
Journal of Agricultural and Food ChemistryMethyleugenol (MTL) and safrole (SFL) are hepatotoxic flavorants with distinct IARC classifications (Group 2A versus 2B), and yet the structural reason for this differential toxicity is unclear. Results showed that MTL was more hepatotoxic than SFL, owing to its more efficient metabolic activation.
Hui Yang +7 more
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Determination of methyleugenol in rodent plasma by high-performance liquid chromatography
Journal of Chromatography B: Biomedical Sciences and Applications, 1995A method has been developed and validated for the analysis of methyleugenol, a volatile flavoring agent, in rodent plasma at concentrations from 0.050 to 10.0 micrograms/ml. The method involves the addition of acetonitrile to the plasma, removal of the protein precipitate, and analysis of the supernatant by reversed-phase (C18) HPLC using an ...
S W, Graves, S, Runyon
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Comparison of GC/MS and NMR for quantification of methyleugenol in food
European Food Research and Technology, 2012Methyleugenol is a substance that is possibly carcinogenic to humans, which may occur in foods containing certain herbs and spices. The European Union has set maximum levels for some product groups, but there is a lack of comprehensive market surveys for this compound.
Sophia Grosch +5 more
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Neuropharmacology, 2018
Feeding can be inhibited by satiety, sickness, or food unpalatability. The central nucleus of the amygdala (CeA) has been considered the key region for processing multiple anorexigenic signals, although the detailed cellular and molecular mechanisms remain largely unclear. Here we identify that methyleugenol (ME), a novel agonist of A type ionotropic γ-
Tailin Zhu +9 more
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Feeding can be inhibited by satiety, sickness, or food unpalatability. The central nucleus of the amygdala (CeA) has been considered the key region for processing multiple anorexigenic signals, although the detailed cellular and molecular mechanisms remain largely unclear. Here we identify that methyleugenol (ME), a novel agonist of A type ionotropic γ-
Tailin Zhu +9 more
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Toxicokinetics of methyleugenol in F344 rats and B6C3F₁ mice.
Xenobiotica; the fate of foreign compounds in biological systems, 20131. Methyleugenol (MEG) has been used as a flavouring agent in food, as a fragrance in cosmetic products, and as an insect attractant. MEG was carcinogenic in both rats and mice following gavage administration. In this study we investigated plasma toxicokinetics of MEG in F344 rats and B6C3F₁ mice of both sexes following single gavage (37, 75, or 150 mg/
S Peter, Hong +6 more
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