Results 161 to 170 of about 1,912 (187)
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Determination of methyleugenol in rodent plasma by high-performance liquid chromatography
Journal of Chromatography B: Biomedical Sciences and Applications, 1995A method has been developed and validated for the analysis of methyleugenol, a volatile flavoring agent, in rodent plasma at concentrations from 0.050 to 10.0 micrograms/ml. The method involves the addition of acetonitrile to the plasma, removal of the protein precipitate, and analysis of the supernatant by reversed-phase (C18) HPLC using an ...
S W, Graves, S, Runyon
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Relaxant and Antispasmodic Actions of Methyleugenol on Guinea-Pig Isolated Ileum
Planta Medica, 2000The effects of methyleugenol (ME) on guinea-pig isolated ileum were studied. ME reversibly relaxed basal tonus (EC50 of 52.2 +/- 18.3 microM), an action unaltered by 0.5 microM tetrodotoxin or 0.5 mM hexamethonium, and relaxed the ileum pre-contracted with 60 mM KCl.
C C, Lima +5 more
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Comparison of GC/MS and NMR for quantification of methyleugenol in food
European Food Research and Technology, 2012Methyleugenol is a substance that is possibly carcinogenic to humans, which may occur in foods containing certain herbs and spices. The European Union has set maximum levels for some product groups, but there is a lack of comprehensive market surveys for this compound.
Sophia Grosch +5 more
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Neuropharmacology, 2018
Feeding can be inhibited by satiety, sickness, or food unpalatability. The central nucleus of the amygdala (CeA) has been considered the key region for processing multiple anorexigenic signals, although the detailed cellular and molecular mechanisms remain largely unclear. Here we identify that methyleugenol (ME), a novel agonist of A type ionotropic γ-
Tailin Zhu +9 more
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Feeding can be inhibited by satiety, sickness, or food unpalatability. The central nucleus of the amygdala (CeA) has been considered the key region for processing multiple anorexigenic signals, although the detailed cellular and molecular mechanisms remain largely unclear. Here we identify that methyleugenol (ME), a novel agonist of A type ionotropic γ-
Tailin Zhu +9 more
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In vitro synergy of eugenol and methyleugenol with fluconazole against clinical Candida isolates
Journal of Medical Microbiology, 2010The speciesCandidais a group of opportunistic pathogenic commensals in immune-compromised patients. Treatment ofCandidainfections is becoming increasingly difficult due to antifungal drug resistance, especially with fluconazole (FLC), which is a commonly used azole. In the present study thein vitroantifungal activity of eugenol (EUG) and methyleugenol (
Aijaz, Ahmad +3 more
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Chemical Research in Toxicology, 1996
Methyleugenol is an allylbenzene food flavoring which has been shown to form DNA and protein adducts, and to cause hepatotoxicity and carcinogenicity in rodents. In order to investigate the nature of the protein adducts, specific antisera were raised by immunizing rabbits with conjugates prepared by coupling 1'-acetoxymethyleugenol, or its acidic ...
I, Gardner +4 more
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Methyleugenol is an allylbenzene food flavoring which has been shown to form DNA and protein adducts, and to cause hepatotoxicity and carcinogenicity in rodents. In order to investigate the nature of the protein adducts, specific antisera were raised by immunizing rabbits with conjugates prepared by coupling 1'-acetoxymethyleugenol, or its acidic ...
I, Gardner +4 more
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Toxicokinetics of methyleugenol in F344 rats and B6C3F₁ mice.
Xenobiotica; the fate of foreign compounds in biological systems, 20131. Methyleugenol (MEG) has been used as a flavouring agent in food, as a fragrance in cosmetic products, and as an insect attractant. MEG was carcinogenic in both rats and mice following gavage administration. In this study we investigated plasma toxicokinetics of MEG in F344 rats and B6C3F₁ mice of both sexes following single gavage (37, 75, or 150 mg/
S Peter, Hong +6 more
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Reactions of tellurium tetrahalides with methyleugenol
Russian Journal of Organic Chemistry, 2015M. V. Musalova +4 more
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Toxicological properties of methyleugenol and methylisoeugenol metabolites
Toxicology Letters, 2012Alexander Thomas Cartus +8 more
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