Results 141 to 150 of about 1,735 (188)

Seasonal Variation of Essential Oil Quantity and Quality in Bay Laurel (<i>Laurus nobilis</i> L.) Leaves from Montenegro. [PDF]

Plants (Basel)
Ilić ZS, Stanojević L, Milenković L, Milenković A, Šunić L, Ilić D, Stanojević J, Cvetković D, Božović D, Kevrešan Ž.   +9 more
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Cytotoxicity and genotoxicity of methyleugenol and related congeners — a mechanism of activation for methyleugenol

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2000
Methyleugenol is a substituted alkenylbenzene found in a variety of foods, products, and essential oils. In a 2-year bioassay conducted by the National Toxicology Program, methyleugenol caused neoplastic lesions in the livers of Fischer 344 rats and B6C3F(1) mice. We were interested in the cytotoxicity and genotoxicity caused by methyleugenol and other
John-Michael Sauer, Charlène A Mcqueen, I Glenn Sipes   +2 more
exaly   +3 more sources

Constituents of aromatic plants: I. Methyleugenol

Fìtoterapìâ, 2000
Methyleugenol (ME) is a natural constituent of the essential oils of a number of plants widely used in foodstuffs as flavouring agents. Its occurrence, routes of intake, and available information on toxicity, kinetics and metabolism are reviewed. In view of the carcinogenic potential of ME, the need to check its presence in food products with effective
Marco Silano, Beatrice Scazzocchio
exaly   +3 more sources

Synthesis, structure and properties of two series of platinum(II) complexes containing methyleugenol or chelating methyleugenol and amine

Polyhedron, 2015
Two series of platinum(II) complexes of the formula [PtCl2(Meug)(Amine)] (1–6, Meug: methyleugenol) and [PtCl(Meug-1H)(Amine)] (7–13, Meug-1H: deprotonated methyleugenol) were synthesized and characterized by elemental analyses, IR,
Tran Thi Da, Nguyen Thi Thanh Chi, Luc Van Meervelt   +2 more
exaly   +2 more sources

Methyleugenol as a surgical anesthetic in rodents

Experientia, 1981
The in vivo administration of 59Fe to the rat accompanied by acetylsalicylic acid (ASA) enhanced significantly counts in blood, spleen, liver and femur without affecting those of the intestine. The results suggest that ASA augments iron absorption either via an inhibitory action on the synthesis of prostaglandins or by a purely chemical mechanism.
E A Carlini, Carlini E A
exaly   +4 more sources

Antinociceptive effect of methyleugenol on formalin-induced hyperalgesia in mice

European Journal of Pharmacology, 2006
The effects of methyleugenol, an essential oil isolated from Asiasari radix, on antinociception were examined using the formalin test in mice. Oral administration of 10 mg/kg methyleugenol significantly decreased the duration of licking and biting behavior in the second phase without affecting that of the first phase, as did diclofenac, a non-steroidal
Mitsutoshi Yuzurihara, Yoshio Kase, Shuichi Takeda   +2 more
exaly   +3 more sources

Physiologically based biokinetic model of bioactivation and detoxification of the alkenylbenzene methyleugenol in rat

Toxicology in Vitro, 2011
The present study defines a physiologically based biokinetic (PBBK) model for the alkenylbenzene methyleugenol in rat based on in vitro metabolic parameters determined using relevant tissue fractions, in silico derived partition coefficients, and physiological parameters derived from the literature. The model was based on the model previously developed
Al-Subeihi, A.A., Spenkelink, A., Rachmawati, N., Boersma, M.G., Punt, A., Vervoort, J.J.M., van Bladeren, P.J., Rietjens, I.M.C.M.   +7 more
openaire   +3 more sources

Methyleugenol hepatocellular cancer initiating effects in rat liver

Food and Chemical Toxicology, 2013
Methyleugenol (MEG), a constituent of plants used in the human diet, is hepatocarcinogenic in rodents. In an experiment to elucidate its mode of action in rat liver, male F344 rats were administered MEG intragastrically at 3 doses per week for up to 16 weeks in an initiation phase, after which half the rats were fed 500 ppm phenobarbital (PB) in the ...
Gary M, Williams, Michael J, Iatropoulos, Alan M, Jeffrey, Jian-Dong, Duan   +3 more
openaire   +3 more sources

Safrole, eugenol and methyleugenol induce intrachromosomal recombination in yeast

Mutation Research - Genetic Toxicology Testing and Biomonitoring of Environmental Or Occupational Exposure, 1989
Deletion of an integrated plasmid, a specific type of intrachromosomal recombination, was evaluated for inducibility with the phenylpropenes safrole, eugenol and methyleugenol in the yeast Saccharomyces cerevisiae. These phenylpropenes are found in food products, spices, pharmaceuticals and clove cigarettes. Safrole and eugenol are known carcinogens in
Robert H Schiestl, R Daniel Gietz, P J Hastings   +2 more
exaly   +3 more sources