Results 11 to 20 of about 1,735 (188)

Carcinogenicity of aspartame, methyleugenol, and isoeugenol

The Lancet Oncology, 2023
Evaluation of the carcinogenicity of aspartame, methyleugenol, and isoeugenol made by a Working Group of 25 scientists from 12 countries at the International Agency for Research on Cancer (IARC)
Riboli E, Beland FA, Lachenmeier DW, Marques MM, Phillips DH, Schernhammer E, Afghan A, Assunção R, Caderni G, Corton JC, de Aragão Umbuzeiro G, de Jong D, Deschasaux-Tanguy M, Hodge A, Ishihara J, Levy DD, Mandrioli D, McCullough ML, McNaughton SA, Morita T, Nugent AP, Ogawa K, Pandiri AR, Sergi CM, Touvier M, Zhang L, Benbrahim-Tallaa L, Chittiboyina S, Cuomo D, DeBono NL, Debras C, de Conti A, El Ghissassi F, Fontvieille E, Harewood R, Kaldor J, Mattock H, Pasqual E, Rigutto G, Simba H, Suonio E, Viegas S, Wedekind R, Schubauer-Berigan MK, Madia F   +44 more
core   +5 more sources

Comparative Transcriptomic Analysis Reveals the Effects of Drought on the Biosynthesis of Methyleugenol in Asarum sieboldii Miq.

Biomolecules, 2021
Asarum sieboldii Miq., a perennial herb in the family Aristolochiaceae, is widely used to treat colds, fever, headache and toothache in China. However, little is known about the drought-tolerance characteristics of A. sieboldii.
Fawang Liu, Tahir Ali, Zhong Liu
doaj   +2 more sources

Isolation of Chavibetol and Methyleugenol from Essential Oil of Pimenta pseudocaryophyllus by High Performance Liquid Chromatography

Molecules, 2018
A high performance liquid chromatography (HPLC) method was developed for the simultaneous isolation, on a semi-preparative scale, of chavibetol and methyleugenol from the crude essential oil of P. pseudocaryophyllus leaves.
Edenilson dos Santos Niculau, Leandro do Prado Ribeiro, Thiago Felipe Ansante, João Batista Fernandes, Moacir Rossi Forim, Paulo Cezar Vieira, José Djair Vendramim, Maria Fátima das Graças Fernandes da Silva   +7 more
doaj   +2 more sources

THE SYNTHESIS OF 1,3-DIMETHYL-6,7-DIMETHOXY-3,4-DIHYDROISOQUINOLINE FROM METHYLEUGENOL : APPLICATION OF RITTER REACTION FOR DIRECTLY CYCLIZATION

Indonesian Journal of Chemistry, 2010
The synthesis of 1,3-dimethyl-6,7-dimethoxy-3,4-dihydroisoquinoline from methyleugenol with application of Ritter reaction for directly cyclization was presented. This research was carried out in 2 steps : (1) Determination of intermediate stability that
M. Farid Rahman, Elvina Dhiaul Iftitah
doaj   +3 more sources

Abundance of DNA adducts of methyleugenol, a rodent hepatocarcinogen, in human liver samples [PDF]

Carcinogenesis, 2013
Methyleugenol is a genotoxic carcinogen in mice and rats, the liver being the primary target tissue. Methyleugenol occurs in fennel and many herbs and spices. Furthermore, methyleugenol-containing plant extracts and chemically prepared methyleugenol are used as flavoring agents. We analyzed surgical human liver samples from 30 subjects for the presence
Kristin, Herrmann, Fabian, Schumacher, Wolfram, Engst, Klaus E, Appel, Kathrin, Klein, Ulrich M, Zanger, Hansruedi, Glatt   +6 more
openaire   +3 more sources

Chemical composition and antimicrobial properties of different basil essential oils chemotypes from Togo

Bangladesh Journal of Pharmacology, 2008
The aerial parts essential oils of Ocimum basilicum (Lamiaceae) from Togo were steam-distilled and investigated for their percentage composition (GC and GC/MS) and in vitro antimicrobial activities.
Koffi Koba, P. W. Poutouli, Christine Raynaud, Jean-Pierre Chaumont, Komla Sanda   +4 more
doaj   +2 more sources

Comparative Transcriptomics Analysis for Gene Mining and Identification of a Cinnamyl Alcohol Dehydrogenase Involved in Methyleugenol Biosynthesis from Asarum sieboldii Miq.

Molecules, 2018
Asarum sieboldii Miq., one of the three original plants of TCM ASARI RADIX ET RHIZOMA, is a perennial herb distributed in central and eastern China, the Korean Peninsula, and Japan.
Jinjie Liu, Chong Xu, Honglei Zhang, Fawang Liu, Dongming Ma, Zhong Liu   +5 more
doaj   +2 more sources

Methyleugenol protects against t-BHP-triggered oxidative injury by induction of Nrf2 dependent on AMPK/GSK3β and ERK activation

Journal of Pharmacological Sciences, 2017
Methyleugenol (Mlg), a natural ingredient of many herbs and used as a flavoring substance in dietary products, inhibits inflammation and oxidative stress.
Junfeng Zhou, Xiaoyuan Ma, Yan Cui, Yang Song, Lei Yao, Yuanyuan Liu, Shanshan Li   +6 more
doaj   +2 more sources

p53 triggers mitochondrial apoptosis following DNA damage-dependent replication stress by the hepatotoxin methyleugenol [PDF]

Cell Death and Disease, 2022
Liver cancer is one of the most frequent tumor entities worldwide, which is causally linked to viral infection, fatty liver disease, life-style factors and food-borne carcinogens, particularly aflatoxins.
Max J. Carlsson, Anastasia S. Vollmer, Philipp Demuth, Daniel Heylmann, Diana Reich, Caroline Quarz, Birgit Rasenberger, Teodora Nikolova, Thomas G. Hofmann, Markus Christmann, Julia A. Fuhlbrueck, Simone Stegmüller, Elke Richling, Alexander T. Cartus, Jörg Fahrer   +14 more
doaj   +2 more sources

Biotransformation of methyleugenol by rat hepatic microsomes

Journal of Chinese Pharmaceutical Sciences, 2014
Methyleugenol (1), one of the main bioactive constituents of the seeds of Myristica fragrans Houtt. (family: Myristicaceae), was incubated with rat hepatic microsomes from rats pretreated with sodium phenobarbital. Eight biotransformation products named (
Guiyun Cao, Xiuwei Yang
openaire   +2 more sources