Results 11 to 20 of about 1,912 (187)

Carcinogenicity of aspartame, methyleugenol, and isoeugenol

The Lancet Oncology, 2023
Evaluation of the carcinogenicity of aspartame, methyleugenol, and isoeugenol made by a Working Group of 25 scientists from 12 countries at the International Agency for Research on Cancer (IARC)
Riboli E, Beland FA, Lachenmeier DW, Marques MM, Phillips DH, Schernhammer E, Afghan A, Assunção R, Caderni G, Corton JC, de Aragão Umbuzeiro G, de Jong D, Deschasaux-Tanguy M, Hodge A, Ishihara J, Levy DD, Mandrioli D, McCullough ML, McNaughton SA, Morita T, Nugent AP, Ogawa K, Pandiri AR, Sergi CM, Touvier M, Zhang L, Benbrahim-Tallaa L, Chittiboyina S, Cuomo D, DeBono NL, Debras C, de Conti A, El Ghissassi F, Fontvieille E, Harewood R, Kaldor J, Mattock H, Pasqual E, Rigutto G, Simba H, Suonio E, Viegas S, Wedekind R, Schubauer-Berigan MK, Madia F   +44 more
core   +5 more sources

Isolation of Chavibetol and Methyleugenol from Essential Oil of Pimenta pseudocaryophyllus by High Performance Liquid Chromatography

Molecules, 2018
A high performance liquid chromatography (HPLC) method was developed for the simultaneous isolation, on a semi-preparative scale, of chavibetol and methyleugenol from the crude essential oil of P. pseudocaryophyllus leaves.
Edenilson dos Santos Niculau, Leandro do Prado Ribeiro, Thiago Felipe Ansante, João Batista Fernandes, Moacir Rossi Forim, Paulo Cezar Vieira, José Djair Vendramim, Maria Fátima das Graças Fernandes da Silva   +7 more
doaj   +2 more sources

Abundance of DNA adducts of methyleugenol, a rodent hepatocarcinogen, in human liver samples [PDF]

Carcinogenesis, 2013
Methyleugenol is a genotoxic carcinogen in mice and rats, the liver being the primary target tissue. Methyleugenol occurs in fennel and many herbs and spices. Furthermore, methyleugenol-containing plant extracts and chemically prepared methyleugenol are used as flavoring agents. We analyzed surgical human liver samples from 30 subjects for the presence
Kristin, Herrmann, Fabian, Schumacher, Wolfram, Engst, Klaus E, Appel, Kathrin, Klein, Ulrich M, Zanger, Hansruedi, Glatt   +6 more
openaire   +3 more sources

THE SYNTHESIS OF 1,3-DIMETHYL-6,7-DIMETHOXY-3,4-DIHYDROISOQUINOLINE FROM METHYLEUGENOL : APPLICATION OF RITTER REACTION FOR DIRECTLY CYCLIZATION [PDF]

Indonesian Journal of Chemistry, 2010
The synthesis of 1,3-dimethyl-6,7-dimethoxy-3,4-dihydroisoquinoline from methyleugenol with application of Ritter reaction for directly cyclization was presented. This research was carried out in 2 steps : (1) Determination of intermediate stability that
M. Farid Rahman, Elvina Dhiaul Iftitah
doaj   +2 more sources

Safety and efficacy of a feed additive consisting of a tincture derived from the flowers of Syzygium aromaticum (L.) Merr. & L.M. Perry (clove tincture) for all animal species (FEFANA asbl) [PDF]

EFSA Journal
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a tincture from the dried flower bud of Syzygium aromaticum (L.) Merr. & L.M.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Birgit Dusemund, Mojca Durjava, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Roberto Edoardo Villa, Ruud Woutersen, Paul Brantom, Andrew Chesson, Josef Schlatter, Johannes Westendorf, Yvette Dirven, Paola Manini, Birgit Dusemund   +23 more
doaj   +2 more sources

Antifungal Efficacy and Mechanisms of Methyleugenol from Asarum Essential Oil Against Rhizoctonia solani Causing Ginseng Damping-Off Disease

Agriculture
Damping-off disease caused by Rhizoctonia solani is a devastating soilborne disease that poses a serious threat to sustainable ginseng (Panax ginseng) production.
Rui Zhang, Xiaolin Chen, Xueqian Yan, Zhongliang Yang, Dandan Zhang, Yingping Wang, Baohui Lu   +6 more
doaj   +2 more sources

Biotransformation of methyleugenol by rat hepatic microsomes

Journal of Chinese Pharmaceutical Sciences, 2014
Methyleugenol (1), one of the main bioactive constituents of the seeds of Myristica fragrans Houtt. (family: Myristicaceae), was incubated with rat hepatic microsomes from rats pretreated with sodium phenobarbital. Eight biotransformation products named (
Guiyun Cao, Xiuwei Yang
openaire   +2 more sources

Methyleugenol: Studies in metabolism and effects on hepatic DNA

, 1999
Methyleugenol is a component of essential oils and is found in many foods and consumer products. Structurally similar to safrole, a known rodent carcinogen, methyleugenol has been shown to be a potent rodent hepatocarcinogen in a National Toxicology ...
Burkey, Jennifer Lewis
core   +5 more sources

Alkenylbenzenes in Foods: Aspects Impeding the Evaluation of Adverse Health Effects

Foods, 2021
Alkenylbenzenes are naturally occurring secondary plant metabolites, primarily present in different herbs and spices, such as basil or fennel seeds. Thus, alkenylbenzenes, such as safrole, methyleugenol, and estragole, can be found in different foods ...
Andreas Eisenreich, Mario E. Götz, Benjamin Sachse, Bernhard H. Monien, Kristin Herrmann, Bernd Schäfer   +5 more
doaj   +1 more source

Safety and efficacy of a feed additive consisting of an essential oil from the leaves of Laurus nobilis L. (laurel leaf oil) for all animal species (FEFANA asbl)

EFSA Journal, 2023
Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of an essential oil from the leaves of Laurus ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Mojca Durjava, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Yolanda Sanz, Roberto Edoardo Villa, Ruud Woutersen, Paul Brantom, Andrew Chesson, Josef Schlatter, Dieter Schrenk, Johannes Westendorf, Paola Manini, Fabiola Pizzo, Birgit Dusemund   +24 more
doaj   +1 more source