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Methylglyoxal – a signaling molecule in plant abiotic stress responses

Free Radical Biology & Medicine, 2018
&NA; Abiotic stresses are the most common harmful factors, adversely affecting all aspects of plants' life. Plants have to elicit appropriate responses against multifaceted effects of abiotic stresses by reprogramming various cellular processes ...
M. G. Mostofa   +5 more
semanticscholar   +1 more source

Methylglyoxal

2014
Methylglyoxal (MG) is a reactive α-dicarbonyl, and may be the most important reactive aldehyde that is primarily generated endogenously in cells and exogenously due to autoxidation process. Interestingly, diabetes was the first disease in which evidence emerged for the increased formation of MG in the body.
openaire   +2 more sources

Methylglyoxal - An emerging biomarker for diabetes mellitus diagnosis and its detection methods.

Biosensors & bioelectronics, 2019
Diabetes Mellitus (DM) is one among the supreme metabolic issues observed in history since 3000 BCE and has gained much interest recently due to the increasing number of diabetic cases every year.
Lakshmishri Ramachandra Bhat   +3 more
semanticscholar   +1 more source

A “Turn-On” Fluorescent Sensor for Methylglyoxal

Journal of the American Chemical Society, 2013
Methylglyoxal (MGO), a dicarbonyl metabolite produced by all living cells, has been associated with a number of human diseases. However, studies of the role(s) MGO plays biologically have been handicapped by a lack of direct methods for its monitoring and detection.
Tina, Wang   +3 more
openaire   +2 more sources

Metabolic Transit of Dietary Methylglyoxal

Journal of Agricultural and Food Chemistry, 2013
Methylglyoxal (MGO) is responsible for the pronounced antibacterial activity of manuka honey, in which it may reach concentrations up to 800 mg/kg. As MGO formed in vivo is discussed to play a role in diabetic complications, the metabolic transit of dietary MGO was studied within a 3 day dietary recall with four healthy volunteers. Determination of MGO
Julia, Degen   +4 more
openaire   +2 more sources

Methylglyoxal and glyoxalase I in atherosclerosis

Biochemical Society Transactions, 2014
Cardiovascular disease, caused predominantly by atherosclerotic plaque rupture, remains one of the leading causes of death. However, the mechanism of plaque rupture remains largely unknown. Recent studies have linked high metabolic activity in inflamed atherosclerotic plaques to the development of plaque rupture.
Hanssen, Nordin M. J.   +2 more
openaire   +3 more sources

Synthesis and metabolism of methylglyoxal, S-D-lactoylglutathione and D-lactate in cancer and Alzheimer's disease. Exploring the crossroad of eternal youth and premature aging.

Ageing Research Reviews, 2019
Both cancer and Alzheimer's disease (AD) are emerging as metabolic diseases in which aberrant/dysregulated glucose metabolism and bioenergetics occur, and play a key role in disease progression. Interestingly, an enhancement of glucose uptake, glycolysis
L. de Bari   +3 more
semanticscholar   +1 more source

Flavour chemistry of methylglyoxal and glyoxal

Chemical Society Reviews, 2012
Methylglyoxal (MGO) and glyoxal (GO), known as reactive carbonyl species, can be generated endogenously and exogenously (human body and food system). They are attracting increased attention because of their relationship with diabetes and flavour generation. In this review, their characteristics relating to flavour chemistry are discussed.
Yu, Wang, Chi-Tang, Ho
openaire   +2 more sources

Methylglyoxal, oxidative stress, and hypertension

Canadian Journal of Physiology and Pharmacology, 2006
Pathogenic mechanisms for essential hypertension are unclear despite striking efforts from numerous research teams over several decades. Increased production of reactive oxygen species (ROS) has been associated with the development of hypertension and the role of ROS in hypertension has been well documented in recent years.
Tuanjie, Chang, Lingyun, Wu
openaire   +2 more sources

Kinetic evaluation of the reaction between methylglyoxal and certain scavenging compounds and determination of their in vitro dicarbonyl scavenging activity.

Food Research International, 2019
This study aimed to investigate the reaction between methylglyoxal and amino acids, polyphenols and sulfur compounds and to provide a new approach for the determination of their dicarbonyl scavenging activities.
E. Cömert, V. Gökmen
semanticscholar   +1 more source

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