Results 51 to 60 of about 135,317 (323)

Methylprednisolone Induces Neuro-Protective Effects via the Inhibition of A1 Astrocyte Activation in Traumatic Spinal Cord Injury Mouse Models

Frontiers in Neuroscience, 2021
Traumatic spinal cord injury (TSCI) leads to pathological changes such as inflammation, edema, and neuronal apoptosis. Methylprednisolone (MP) is a glucocorticoid that has a variety of beneficial effects, including decreasing inflammation and ischemic ...
Hong-jun Zou, Shi-Wu Guo, Lin Zhu, Xu Xu, Jin-bo Liu   +4 more
doaj   +1 more source

Prophylactic methylprednisolone to reduce inflammation and improve outcomes from one lung ventilation in children: a randomized clinical trial. [PDF]

, 2015
BACKGROUND: One lung ventilation (OLV) results in inflammatory and mechanical injury, leading to intraoperative and postoperative complications in children. No interventions have been studied in children to minimize such injury.
Brislin, Robert P., Brown, Melinda, Dabney, Kirk W., Fisher, Alicia Olivant, Katz, Douglas A., Mackenzie, William G., McCoy, Matt, Reichard, Kirk W., Rodriguez, Maria E., Shaffer, Thomas H., Shah, Suken A., Theroux, Mary C.   +11 more
core   +2 more sources

Evaluation of the Efficacy and Safety of Satralizumab in a Pregnant NMOSD Patient With AQP4/MOG‐IgG Dual Seropositive: A Case Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Iatrogenic meningitis

Arquivos de Neuro-Psiquiatria, 2013
Iatrogenic meningitis can be caused by a number of mechanisms. The recent case reports of fungal meningitis after application of epidural methylprednisolone caused warning in the medical community.
Eduardo Genaro Mutarelli, Tarso Adoni
doaj   +1 more source

True infliximab resistance in rheumatoid arthritis: a role for lymphotoxin α? [PDF]

, 2004
Background: The combination of methotrexate and the anti-tumour necrosis factor (TNF) antibody infliximab is a very effective treatment for rheumatoid arthritis (RA). However, a proportion of patients are not responsive to this treatment. Inefficacy may
Bingham, S.J., Buch, M.H., Conaghan, P., Emery, P., Quinn, M.A., Veale, D.   +5 more
core   +2 more sources

Assessment of Pain Types in Recently Diagnosed Patients With Inflammatory Arthritis

Arthritis Care &Research, EarlyView.
Objective Up to 40% of patients with inflammatory arthritis (IA) experience persistent pain, traditionally thought to be associated with a shift from peripherally to centrally mediated pain during the disease course in some patients. We assessed sensory profiles of recently diagnosed individuals with IA, hypothesizing that pain reported at this early ...
Zoe Rutter‐Locher, Sam Norton, Joseph L. Taylor, Bina Menon, Tom Esterine, Ruth Williams, Leonie S. Taams, Kirsty Bannister, Bruce W. Kirkham   +8 more
wiley   +1 more source

The Effects of Methylprednisolone and Hyaluronic Acid on the Endometrium in Experimentally Induced Asherman Syndrome Rat Models: A Prospective Laboratory Study

Medicina
Background and Objectives: The current study was designed as a prospective laboratory investigation to evaluate the histopathological effects and VEGF (vascular endothelial growth factor) expression in uterine tissue following treatment with a ...
Mehmet Genco, Merve Genco, Fisun Vural, Nermin Koç   +3 more
doaj   +1 more source

Judicious use of low-dosage corticosteroids for non-severe COVID-19: A case report

Open Medicine, 2021
Inflammation-mediated lung injury in severe cases of infection with SARS-CoV-2, the aetiological agent of Coronavirus disease 2019 (COVID-19), can lead to respiratory failure and death, and therapies that block or ameliorate lung injury-associated ...
Zhang Jian, Tian Zigang, Feng Lina, Yang Zhongming, Zou Bo, Li Kun, Zhang Yingliang, Wang Yaguo, Fleming Joy, Cui Wenyu   +9 more
doaj   +1 more source

Kinetics of Severity Biomarkers and Immunological Features of Methylprednisolone Therapy for Severe COVID-19 Patients

Frontiers in Immunology, 2022
In contrast to dexamethasone, the clinical efficacy of methylprednisolone (MP) remains controversial, and a systems biology study on its mechanism is lacking. In this study, a total of 38 severe COVID-19 patients were included. The demographics, clinical
Qinghong Fan, Kai Deng, Huang Huang, Ruiying He, Xizi Deng, Yun Lan, Yizhou Tan, Weilie Chen, Yaping Wang, Xilong Deng, Fengyu Hu, Feng Li, Feng Li   +12 more
doaj   +1 more source