Results 51 to 60 of about 167,693 (338)

Treatment of immunoglobulin-resistant kawasaki disease: a Bayesian network meta-analysis of different regimens

Frontiers in Pediatrics, 2023
BackgroundThis study aimed to gather evidence from clinical trials on the efficacy and safety of the available treatments for intravenous immunoglobulin (IVIG)-resistant Kawasaki disease (KD) in children.MethodsThis work adopted the Newcastle–Ottawa ...
Yan Pan, Qihong Fan, Luoyi Hu
doaj   +1 more source

Rapid Administration of High-Dose Intravenous Methylprednisolone Improves Visual Outcomes After Optic Neuritis in Patients With AQP4-IgG-Positive NMOSD

Frontiers in Neurology, 2020
Objective: The purpose of this study was to elucidate the rapid impact of high-dose intravenous methylprednisolone pulse therapy (1,000 mg/day for 3 days) on the eventual visual prognosis in patients with serum anti-aquaporin-4 immunoglobulin G (AQP4-IgG)
T. Akaishi, Takayuki Takeshita, Noriko Himori, Toshiyuki Takahashi, T. Misu, R. Ogawa, K. Kaneko, J. Fujimori, Michiaki Abe, T. Ishii, K. Fujihara, M. Aoki, T. Nakazawa, I. Nakashima   +13 more
semanticscholar   +1 more source

Methylprednisolone versus intravenous immune globulin as an initial therapy in adult primary immune thrombocytopenia [PDF]

The Korean Journal of Internal Medicine, 2019
Background/Aims Few studies have addressed whether there are differences in clinical efficacy between intravenous methylprednisolone (methyl-Pd) and intravenous immunoglobulin (IVIg) use.
Chul Hee Kim, Yoon Seok Choi, Ji Young Moon, Duck Yong Kim, So Yeon Lee, Hyo Jin Lee, Hwan Jung Yun, Samyong Kim, Deog Yeon Jo, Ik Chan Song   +9 more
doaj   +1 more source

Randomized preclinical study of machine perfusion in vascularized composite allografts

BJS (British Journal of Surgery), EarlyView., 2020
This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin, J. P. Stone, J. Kerr, A. Geraghty, L. Joseph, A. Montero‐Fernandez, J. K. Wong, J. E. Fildes   +7 more
wiley   +1 more source

Efficacy and safety of low dose oral prednisolone as compared to pulse intravenous methylprednisolone in managing moderate severe Graves′ orbitopathy: A randomized controlled trial

Indian Journal of Endocrinology and Metabolism, 2015
Background: High dose oral prednisolone (100 mg/day) in Graves′ orbitopathy (GO) is limited by lesser response, and greater side-effects compared to intravenous (iv) methylprednisolone. Low dose oral prednisolone has not been evaluated in GO.
Ajitesh Roy, Deep Dutta, Sujoy Ghosh, Pradip Mukhopadhyay, Satinath Mukhopadhyay, Subhankar Chowdhury   +5 more
doaj   +1 more source

Use of Corticosteroids in Coronavirus Disease 2019 Pneumonia: A Systematic Review of the Literature

Frontiers in Medicine, 2020
The aim was to investigate the effectiveness of glucocorticoid therapy in patients with COVID-19. A systematic search of the literature across nine databases was conducted from inception until 15th March 2020, following the PRISMA guidelines.
Nicola Veronese, Jacopo Demurtas, Jacopo Demurtas, Lin Yang, Lin Yang, Roberto Tonelli, Roberto Tonelli, Mario Barbagallo, Pierluigi Lopalco, Erik Lagolio, Stefano Celotto, Damiano Pizzol, Liye Zou, Mark A. Tully, Petre Cristian Ilie, Mike Trott, Guillermo F. López-Sánchez, Lee Smith   +17 more
doaj   +1 more source

Methylprednisolone Promotes Mycobacterium smegmatis Survival in Macrophages through NF-κB/DUSP1 Pathway

Microorganisms, 2023
Background: Mycobacterium tuberculosis (M. tuberculosis) is the causative agent of tuberculosis. As an important component of host immunity, macrophages are not only the first line of defense against M.
Anlong Li, Yonglin He, Chun Yang, Nan Lu, Jiajia Bao, Sijia Gao, Felycia Fernanda Hosyanto, Xintong He, Huichao Fu, Huajian Yan, Ningyu Ding, Lei Xu   +11 more
doaj   +1 more source

Judicious use of low-dosage corticosteroids for non-severe COVID-19: A case report

Open Medicine, 2021
Inflammation-mediated lung injury in severe cases of infection with SARS-CoV-2, the aetiological agent of Coronavirus disease 2019 (COVID-19), can lead to respiratory failure and death, and therapies that block or ameliorate lung injury-associated ...
Zhang Jian, Tian Zigang, Feng Lina, Yang Zhongming, Zou Bo, Li Kun, Zhang Yingliang, Wang Yaguo, Fleming Joy, Cui Wenyu   +9 more
doaj   +1 more source

Minocycline synergizes with corticosteroids in reducing colitis severity in mice via the modulation of pro-inflammatory molecules

Frontiers in Pharmacology, 2023
Background: A few studies have highlighted the anti-inflammatory properties of minocycline in reducing colitis severity in mice, but its molecular mechanism is not fully understood.
Maitham A. Khajah, Sanaa Hawai, Ahmad Barakat, Aisha Albaloushi, Maha Alkharji, Willias Masocha   +5 more
doaj   +1 more source

A case of multisystem inflammatory syndrome in children (MIS-C) mimicking Kawasaki disease

Sri Lanka Journal of Medicine, 2021
Introduction: Severe acute respiratory syndrome coronavirus-2 infection has emerged as a multisystem disorder during the pandemic of Coronavirus disease of 2019 (Covid-19).
M. Rathnayake, L. Dassanayake, A. Fernando, A. Sadikeen   +3 more
doaj   +1 more source