Are We Considering All the Potential Drug-Drug Interactions in Women's Reproductive Health? A Predictive Model Approach. [PDF]
Garcia-Acero P +6 more
europepmc +1 more source
Glutathione-PEGylated liposomal methylprednisolone in comparison to free methylprednisolone: slow release characteristics and prolonged lymphocyte depression in a first-in-human study. [PDF]
Kanhai KMS +6 more
europepmc +1 more source
Corticosteroids for treating sepsis in children and adults. [PDF]
Annane D +8 more
europepmc +1 more source
Targeted nanoliposomes for precision rheumatoid arthritis therapy: a review on mechanisms and in vivo potential. [PDF]
Girase R +9 more
europepmc +1 more source
Revolutionizing rheumatoid arthritis therapy: the potential of lipid nanocarriers. [PDF]
Alarcon JF +8 more
europepmc +1 more source
Histoplasmosis in Immunocompromised and Immunocompetent Patients in Guadeloupe. [PDF]
Lahuna C +6 more
europepmc +1 more source
Immunosuppressive therapy management during sepsis in kidney transplant recipients: a prospective multicenter study. [PDF]
Rivet V +12 more
europepmc +1 more source
Kinetics of methylprednisolone and its hemisuccinate ester
Methylprednisolone in the form of its hemisuccinate ester was injected intravenously in doses of 10 mg/kg and 63.1 mg. Plasma levels of methylprednisolone and of the ester were measured and their kinetics were calculated. Results indicate dose dependency in the kinetics of both. About 10% of the dose was excreted unchanged as hemisuccinate in the urine,
Hartmut Derendorf +2 more
exaly +4 more sources
Pharmacokinetics of Methylprednisolone Hemisuccinate and Methylprednisolone in Chronic Liver Disease
The disposition of methylprednisolone (MP) and its prodrug hemisuccinate (MPHS) was assessed in six middle‐aged patients with chronic liver disease (CLD) and compared with six younger, healthy subjects after a single IV dose of 25.4 mg of MPHS. Blood and urine samples were collected over 12 hours.
Elizabeth A Ludwig, William J Jusko
exaly +4 more sources

