Results 71 to 80 of about 334 (89)
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Biomedical Applications, 1985
A rapid method for the measurement of methylprednisolone and its 21-hemisuccinate ester in plasma and urine following high dose pulse therapy is described. The drugs were extracted using Extrelut columns, eluted with ethyl acetate which was evaporated to dryness and the residue was reconstituted in chromatographic mobile phase.
exaly +3 more sources
A rapid method for the measurement of methylprednisolone and its 21-hemisuccinate ester in plasma and urine following high dose pulse therapy is described. The drugs were extracted using Extrelut columns, eluted with ethyl acetate which was evaporated to dryness and the residue was reconstituted in chromatographic mobile phase.
exaly +3 more sources
Analysis of cortisol, methylprednisolone, and methylprednisolone hemisuccinate
Biomedical Applications, 1984Stanley J Szefler, William Jusko
exaly +2 more sources
Successful rapid desensitization to methylprednisolone sodium hemisuccinate: A case report
Journal of Allergy and Clinical Immunology: in Practice, 2014Ricardo Madrigal-Burgaleta +1 more
exaly +3 more sources
Comparative Pharmacokinetics of Methylprednisolone Phosphate and Hemisuccinate in High Doses
Pharmaceutical Research, 1988The pharmacokinetics of methylprednisolone and two methylprednisolone esters, the phosphate and the hemisuccinate, were investigated after intravenous administration of the esters to 12 healthy male subjects in two different doses (250 and 1000 mg). Methylprednisolone was formed more rapidly from phosphate than from hemisuccinate.
H, Möllmann +5 more
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Therapeutic Drug Monitoring, 1992
A reversed-phase high-performance liquid chromatographic (RP-HPLC) method for the measurement of methylprednisolone hemisuccinate (MPHS) and its metabolites methylprednisolone (MP), 20-alpha- (20a-HMP), and 20-beta-hydroxymethylprednisolone (20b-HMP) in urine is described.
G J, Lawson +3 more
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A reversed-phase high-performance liquid chromatographic (RP-HPLC) method for the measurement of methylprednisolone hemisuccinate (MPHS) and its metabolites methylprednisolone (MP), 20-alpha- (20a-HMP), and 20-beta-hydroxymethylprednisolone (20b-HMP) in urine is described.
G J, Lawson +3 more
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International Journal of Pharmaceutics, 2014
The aims of this study were to assess the tissue permeability of the bladder and to characterize the transport of four drugs displaying different physico-chemical properties and commonly used in intravesical delivery, through porcine bladder. The transport of aluminium through porcine bladder was assessed by using a vertical static diffusion cell ...
Céline, Moch +5 more
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The aims of this study were to assess the tissue permeability of the bladder and to characterize the transport of four drugs displaying different physico-chemical properties and commonly used in intravesical delivery, through porcine bladder. The transport of aluminium through porcine bladder was assessed by using a vertical static diffusion cell ...
Céline, Moch +5 more
openaire +2 more sources
Separation Science and Technology, 2013
In-situ Attenuated total reflectance Fourier transform infrared (ATR-FTIR), focused beam reflectance measurement (FBRM) and particle video microscope (PVM) have been used simultaneously in this work to monitor the concentration, supersaturation, chord length distribution, and crystal habit, respectively, during a cooling crystallization process of ...
Yang-Hui Luo +3 more
openaire +1 more source
In-situ Attenuated total reflectance Fourier transform infrared (ATR-FTIR), focused beam reflectance measurement (FBRM) and particle video microscope (PVM) have been used simultaneously in this work to monitor the concentration, supersaturation, chord length distribution, and crystal habit, respectively, during a cooling crystallization process of ...
Yang-Hui Luo +3 more
openaire +1 more source
Journal of chromatography, 1984
A sensitive, selective, and reproducible high-performance liquid chromatographic assay for the simultaneous measurement of cortisol and methylprednisolone using dexamethasone as the internal standard is presented. Samples are extracted with methylene chloride, washed with sodium hydroxide and then water, and chromatographed on a microparticle silica ...
W F, Ebling, S J, Szefler, W J, Jusko
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A sensitive, selective, and reproducible high-performance liquid chromatographic assay for the simultaneous measurement of cortisol and methylprednisolone using dexamethasone as the internal standard is presented. Samples are extracted with methylene chloride, washed with sodium hydroxide and then water, and chromatographed on a microparticle silica ...
W F, Ebling, S J, Szefler, W J, Jusko
openaire +1 more source