A non‐canonical C16 sesquiterpene synthase from Morganella morganii produces the unusual scaffold descartane. Its cyclisation mechanism was rationalised by isotopic labelling experiments and DFT calculations. Site‐directed mutagenesis altered enzyme function, resulting in alternative products, including voltairene, which requires a different ...
Kexin Yang +4 more
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<i>Maackia amurensis</i> seed lectin inhibits oral squamous cell carcinoma tumorigenesis by suppressing N6-methyladenosine modification-mediated SRY-box transcription factor 2 expression. [PDF]
Du Y +6 more
europepmc +1 more source
Statement of Retraction: Methyltransferase-like 3 silenced inhibited the ferroptosis development via regulating the glutathione peroxidase 4 levels in the intracerebral hemorrhage progression. [PDF]
europepmc +1 more source
SETDB1 promotes gastric cancer progression via UPR and mTOR pathway. [PDF]
Qiao J +7 more
europepmc +1 more source
Temperature-dependent dynamics of DNA methylation and plasmid copy number in Yersinia pestis. [PDF]
D N K +11 more
europepmc +1 more source
Seasonal Fluctuations of Plastochromanol‐8 and α‐Tocopherol Amounts in the Leaves of Cecropia Trees
ABSTRACT Plastochromanol‐8 (PC‐8) is a homologue of γ‐tocotrienol with a longer side chain (eight instead of three isoprene units) and therefore also a representative of the tocochromanol (vitamin E) group. PC‐8 has been determined in various plants and seeds, with Cecropia sp. leaves showing unusually high levels.
Rosalie Ormos, Jörg Rau, Walter Vetter
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Field samples from breeder duck farms with egg‐production decline were subjected to viral detection, genome sequencing, and virus isolation. Experimental infection demonstrated that duck orbivirus (DORV) causes a significant and persistent reduction in egg production in breeder ducks.
Bing Li +18 more
wiley +1 more source
The methyltransferase activity of Dot1L is essential for Xenopus tropicalis tadpole development and survival. [PDF]
Louis EM, Luu N, Sachs LM, Shi YB.
europepmc +1 more source
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu +8 more
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