Results 171 to 180 of about 217,730 (262)

Advances in research on RNA methylation and its role in the immune microenvironment of gastrointestinal tumors. [PDF]

Front Cell Dev Biol
Duan Y, Xu Z, Wen K, Xue C, Shen R, Gu X.   +5 more
europepmc   +1 more source

Precision Chemistry for Protein Lysine Modification

Chemistry – A European Journal, EarlyView.
Selective modification of lysine residues is challenging due to their similar intrinsic reactivity. Inspired by enzymatic recognition, ligand‐guided electrophiles enable site‐selective labeling and functionalization, while ligand‐guided catalyses achieve regioselective installation of bio‐relevant post‐translational modifications.
Mayu Onoda, Motomu Kanai
wiley   +1 more source

Deletion of phosphatidylethanolamine methyltransferase promotes the spontaneous development of hepatic steatosis, inflammation, and fibrosis in young mice. [PDF]

Clin Sci (Lond)
Perumal SK, Rajamanickam R, Arumugam MK, Chava S, Bellamkonda R, Mahalingam S, Osna NA, Trujillo-Gonzalez I, Fisher KW, Rasineni K, Kharbanda KK.   +10 more
europepmc   +1 more source

Clinical Functional Assignment of TPMT and NUDT15 Alleles by the Clinical Pharmacogenetics Implementation Consortium Pharmacogene Curation Expert Panel

Clinical Pharmacology &Therapeutics, EarlyView.
The Clinical Pharmacogenetics Implementation Consortium (CPIC) TPMT/NUDT15 Pharmacogene Curation Expert Panel (PCEP) conducted a comprehensive review of clinical, laboratory, and computational evidence to determine the clinical function assignments for TPMT and NUDT15 star alleles.
Bailey M. Tibben, Maud Maillard, Victoria M. Pratt, Ann M. Moyer, Debbie M. Figueroa, Michelle Whirl‐Carrillo, Andrea Gaedigk, Gabriele Stocco, Matthias Schwab, Kelly E. Caudle, Jun J. Yang   +10 more
wiley   +1 more source

Update of the Methyltransferase Gene Family: Classification, Evolution and Biological Functions. [PDF]

Hum Genomics
Katsafadou AI, Falnes PØ, Bruford E, Braschi B, Hanson QM, Hall MD, Thompson DC, Nebert DW, Vasiliou V.   +8 more
europepmc   +1 more source

An accessible microfluidic perfusion platform for time‐restricted control of zebrafish embryonic patterning

Developmental Dynamics, EarlyView.
Abstract Understanding the dynamic nature of developmental networks requires live imaging techniques capable of capturing real‐time developmental processes in wild‐type and mutant embryos as they are exposed to pharmacological perturbations. A peculiar developmental patterning process in early vertebrate embryos is the sequential segmentation of ...
Mohammed Nakhuda, M. Fethullah Simsek
wiley   +1 more source

DNA Methyltransferase [PDF]

, 2020
openaire   +1 more source

A proteomic investigation of forebrain regeneration in the leopard gecko (Eublepharis macularius)

Developmental Dynamics, EarlyView.
Our investigation reveals ontogenetic, injury‐ and regeneration‐associated proteomic changes in the leopard gecko forebrain. Abstract Background The ability to replace lost or damaged neurons following an injury is termed reactive neurogenesis. Although reactive neurogenesis has been reported in several lizard species, the molecular mechanisms ...
Alexandra I. Noble, Samantha L. Payne, Matthew K. Vickaryous   +2 more
wiley   +1 more source

Natural compounds of medicinal plants as a source for novel anti-orthopoxvirus medications. [PDF]

Life Med
Makhlouf EA, El-Shiekh RA, Okba MM, Ashour HM.   +3 more
europepmc   +1 more source

Associations Between Microbial Depletion and Autonomic Dysregulation in Binge‐Eating Disorder

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective The interplay between the gut microbiome and autonomic nervous system remains unexplored in binge‐eating disorder (BED). We aimed to explore specific microbial alterations in BED and examine their potential association with cardiac vagal tone as a distinct bio‐behavioral phenotype.
Shuang Liang, Esben Strodl, Leanne Barron, Matthew Bambling, Luis Vitetta   +4 more
wiley   +1 more source