Delineation of the active site of MtgB, a cobalamin-dependent glycine betaine methyltransferase. [PDF]
Picking J +5 more
europepmc +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
RNA methyltransferase NSUN2 enhances vasculogenic mimicry and malignant progression of cervical cancer through upregulation of MMP-9. [PDF]
Luo J +8 more
europepmc +1 more source
Ketogenic diet for infantile epileptic spasms
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury +3 more
wiley +1 more source
Comparative analysis of Borrelia's Defence mechanisms and their impact on genetic manipulation of low-passage isolates of <i>Borrelia afzelii</i> and <i>Borrelia garinii</i>. [PDF]
Ruivo M +4 more
europepmc +1 more source
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka +4 more
wiley +1 more source
HPD is an m<sup>6</sup>A Methyltransferase that Protects Colorectal Cancer Cells from Ferroptotic Cell Death by m<sup>6</sup>A Methylating SLC7A11/GPX4. [PDF]
Wang J +17 more
europepmc +1 more source
Wheat DNA Methyltransferase TaMET1 Negatively Regulates Salicylic Acid Biosynthesis to Facilitate Powdery Mildew Susceptibility. [PDF]
Ge P, Chen W, Liu J, Wang X, Chang C.
europepmc +1 more source

