Results 261 to 270 of about 365,379 (338)

RNMT-dependent RNA cap methylation in health and disease. [PDF]

Biochem J
Mills JG, Hepburn LA, Cowling VH.
europepmc   +1 more source

Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss

iMetaMed, EarlyView.
As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu, Cenlan Bu, Qinzheng Xu, Xi Cheng, Junrong Zhang, Jinling Chen, Yun‐Zhao Xu   +6 more
wiley   +1 more source

Furamidine, a methyltransferase inhibitor, is a potential anti-Babesia spp. chemotherapeutic. [PDF]

Parasitol Res
Liang Q, Li X, Zhang X, Zhang Y, Wang J, Liu Z, Ye Y, Bai Y, Zhao S, Luo J, You C, Yin H, Guan G.   +12 more
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Magnetic resonance imaging fractal analysis of O(6)-methylguanine-DNA methyltransferase promoter methylation status in isocitrate dehydrogenase wild-type glioblastoma. [PDF]

Quant Imaging Med Surg
Xue C, Wang K, Dong W, Han T, Zhou Q, Zhang P, Liang L, Wang P, Zhou J, Guan S, Liu X.   +10 more
europepmc   +1 more source

Evolutionary Origins and Functional Diversification of 2′-O-Methyltransferases: Insights from Phylogenetic and Structural Analysis [PDF]

Sainan Wang, Xiaoxia Liu, Lang Lei, Qiang Wang, Zhu‐Qing Shao, Yang Liu   +5 more
openalex   +1 more source

Is Micronucleus Assay a Suitable Biomarker for Evaluating the Cancer Risk in Professionals Exposed to Antineoplastic Drugs? A Systematic Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT The widespread use of antineoplastic drugs in cancer treatment has led to significant concerns regarding the potential health risks posed to healthcare professionals involved in the preparation, administration, and handling of these chemical compounds, including genotoxicity.
Thiago Guedes Pinto, Lorrany da Silva Avanci, Gabriel Carvalhal de Aguiar, Daniel Vitor de Souza, Patricia Ramos Cury, Ana Claudia Muniz Renno, Daniel Araki Ribeiro   +6 more
wiley   +1 more source

Transcription, Maturation and Degradation of Mitochondrial RNA: Implications for Innate Immune Response. [PDF]

Biomolecules
Yan C, Yu J, Lyu H, Xiao S, Guo D, Zhang Q, Zhang R, Tang J, Song Z, Zhou C.   +9 more
europepmc   +1 more source

Identification of a De Novo MAGEL2 Pathogenic Variant in Schaaf–Yang Syndrome and the Importance of Paternal Allele Confirmation

Journal of Clinical Laboratory Analysis, EarlyView.
This study reports a de novo MAGEL2 pathogenic variant in a patient with Schaaf–Yang syndrome, confirmed through methylation‐sensitive analysis. Combining genomic sequencing with methylation assays helps accurately determine the parental origin of MAGEL2 mutations.
Youn‐Ji Hong, Misun Yang, Hyeon Jeong Kwon, Jooyoung Cha, Ja‐Hyun Jang, Sung Eun Wang, Eun Sun Lee, Mi‐Ae Jang   +7 more
wiley   +1 more source

Molecular mechanism of modified Yigong San formula against colorectal cancer <i>via</i> EZH2/METTL3/SOX4 pathway-mediated apoptosis. [PDF]

World J Gastrointest Oncol
Wang J, Zhang XW, Tang BW, Li Z, Song N.
europepmc   +1 more source