Results 261 to 270 of about 292,501 (293)

An Integrative Analysis of O6-Methylguanine-DNA Methyltransferase (MGMT) Methylation and the Single-Nucleotide Polymorphism (SNP) rs1625649 Reveals Distinct Survival Patterns in Glioblastoma: A Retrospective Study. [PDF]

Cureus
Agarwal K, Raghuvanshi S, Bhalla S, Raghuvanshi S, Singh A, Singh A, Ojha BK.   +6 more
europepmc   +1 more source

RNA m1A methyltransferase TRMT61A promotes colorectal tumorigenesis by enhancing ONECUT2 mRNA stability and is a potential therapeutic target

Cancer Communications, EarlyView.
Abstract Background The role of N1‐methyladenosine (m1A) in cancer is poorly understood. Here we explored the function of RNA methyltransferase TRNA methyltransferase 61A (TRMT61A) in colorectal cancer (CRC) and its potential as a therapeutic target. Methods RNA m1A levels were assessed through liquid chromatography‐mass spectrometry.
Xiaoting Zhang, Na Qin, Fenfen Ji, Hao Su, Haiyun Shang, Hongyan Chen, Dan Huang, Qing Li, Jing Ren, Weixin Liu, Yifei Wang, Wei Kang, Jiabin Wu, Chi‐Chun Wong, Zongwei Cai, Matthew Tak Vai Chan, William Ka Kei Wu, Jun Yu, Huarong Chen   +18 more
wiley   +1 more source

Unfolded protein response kinase PERK supports survival and metastasis of circulating tumor cell clusters via SAM synthesis and H3K4me3‐dependent PDGFB signaling

Cancer Communications, EarlyView.
Abstract Background Metastasis is the leading cause of cancer‐related mortality, with circulating tumor cell (CTC) clusters serving as highly efficient precursors of distant metastasis. Survival of CTC clusters in the bloodstream is the primary contributor to tumor metastasis.
Rui Tang, Yan Sun, Ao Deng, Jiahe Liu, Peijin Dai, Jing Chen, Chaoqun Deng, Hui Liu, Yuhang Hai, Yanran Tong, Yan‐e Du, Manran Liu, Haojun Luo   +12 more
wiley   +1 more source

Beyond Methane Oxidation: The Protein Landscape of ANME-2a Reveals an Integrated System for Diazotrophy and Membrane Fortification. [PDF]

Environ Microbiol Rep
Silva SSE, de Avila NB, da Silva AW, da Silva LRF, Prado MR, Beppler MA, Dos Santos AR.   +6 more
europepmc   +1 more source

Chemical Composition and Antibacterial Potential of Lavandula latifolia and Lavandula angustifolia Essential Oils Against Bacillus cereus Isolated From Pipelines of Dairy Industry

Chemistry &Biodiversity, EarlyView.
1,8‐Cineole, limonene, and camphor were abundant in Algerian Lavandula latifolia essential oil, whereas linalol and linalyl acetate were in Lavandula angustifolia. MIC and MBC results revealed L. latifolia oil was the most effective against Bacillus cereus. Hexyl butyrate and lavandulyl acetate, among others, bound efficiently to the active site of the
Mounir Saifi, Nassima Didouh, Nadia Aissaoui, Zahia Khiri, Khadidja Medjahdi, Rachid Achek, Ismail Daoud, Ricardo Araujo   +7 more
wiley   +1 more source

Alpha-centractin is a novel substrate of SETD3 methyltransferase <i>in vitro</i>. [PDF]

PeerJ
Witecka A, Emmel P, Ślusarczyk K, Kamińska JZ, Zaród M, Ishikawa T, Drożak J.   +6 more
europepmc   +1 more source

Peptide Arginases from Cryptic Pathways Install Ornithine Residues in Uncharacterized Members of Orphan RiPP Families

ChemBioChem, EarlyView.
The incorporation of the non‐proteinogenic amino acid ornithine into antibiotic peptides has shown potential in influencing antibacterial efficacy. Novel peptide arginases from cryptic ribosomally synthesized and post‐translationally modified peptide (RiPP) pathways are identified and found to incorporate ornithine residues into various peptide ...
Isabel P.‐M. Pfeiffer, Maria‐Paula Schröder, Panagiota‐Hanna Koutsandrea, Giovanni A. Vitale, Daniela Herrera‐Rosero, Christian Geibel, Daniel Petras, Jörn Piel, Anna L. Vagstad, Silja Mordhorst   +9 more
wiley   +1 more source

Multifaceted roles of CARM1 beyond histone arginine methylation. [PDF]

Exp Mol Med
Cho Y, Kim YK.
europepmc   +1 more source

Dietary Berberine Reduced Oxido‐Inflammatory Stress in Rats' Livers and Kidneys, Supplemented from Prepuberty to Adulthood

ChemFoodChem, EarlyView.
Berberine (BER) demonstrates significant protective effects on the hepatorenal system in rats, mediated through various cellular and molecular mechanisms spanning from the prepubertal stage through adulthood. These mechanisms encompass antioxidant, anti‐inflammatory, and anti‐apoptotic activities, in addition to modulation of essential signalling ...
Solomon Owumi, Bayode Oluwawibe, Harieme Agbarogi, Moses T. Otunla, Uche Arunsi, Jesutosin O. Babalola, Chioma Irozuru, Chima Amadi, Ahmad Altayyar   +8 more
wiley   +1 more source

Identification of novel small molecule inhibitors targeting multiple methyltransferase like proteins against hepatocellular carcinoma. [PDF]

Sci Rep
Morshed MN, Parvez SA, Akanda RI, Saha MK, Fardous J, Alam M, Zhao Y, Franco OE, Hosen MJ.   +8 more
europepmc   +1 more source