Results 51 to 60 of about 154,259 (119)
Highly Iterated Palindromic Sequences (HIPs) and Their Relationship to DNA Methyltransferases
Life, 2015 The sequence GCGATCGC (Highly Iterated Palindrome, HIP1) is commonly found in high frequency in cyanobacterial genomes. An important clue to its function may be the presence of two orphan DNA methyltransferases that recognize internal sequences GATC and ...
Jeff Elhai
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Biochemical and Biophysical Characterisation of the Hepatitis E Virus Guanine-7-Methyltransferase
Molecules, 2022 Hepatitis E virus (HEV) is an understudied pathogen that causes infection through fecal contaminated drinking water and is prominently found in South Asian countries.
Preeti Hooda +13 more
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The RSNA-ASNR-MICCAI BraTS 2021 Benchmark on Brain Tumor Segmentation and Radiogenomic Classification [PDF]
arXiv, 2021 The BraTS 2021 challenge celebrates its 10th anniversary and is jointly organized by the Radiological Society of North America (RSNA), the American Society of Neuroradiology (ASNR), and the Medical Image Computing and Computer Assisted Interventions (MICCAI) society.
arxiv
Journal of Fungi, 2022 Tea-oil tree (Camellia oleifera Abel.) is a unique woody edible oil species in China. Anthracnose is the common disease of Ca. oleifera, which affected the production and brought huge economic losses.
Yalan Gao, Shengpei Zhang, He Li
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H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation [PDF]
arXiv, 2013 Enhancers play a central role in cell-type-specific gene expression and are marked by H3K4me1/2. Active enhancers are further marked by H3K27ac. However, the methyltransferases responsible for H3K4me1/2 on enhancers remain elusive. Furthermore, how these enzymes function on enhancers to regulate cell-type-specific gene expression is unclear.
arxiv
A recognition of exosomes as regulators of epigenetic mechanisms in central nervous system diseases
Frontiers in Molecular NeuroscienceExosomes, vesicular structures originating from cells, participate in the conveyance of proteins and nucleic acids. Presently, the centrality of epigenetic modifications in neurological disorders is widely acknowledged.
Shunxin Hu +5 more
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An emerging maestro of immune regulation: how DOT1L orchestrates the harmonies of the immune system
Frontiers in ImmunologyThe immune system comprises a complex yet tightly regulated network of cells and molecules that play a critical role in protecting the body from infection and disease.
Liam Kealy +4 more
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Frontiers in Plant Science, 2019 Aposporous apomictic plants form clonal maternal seeds by inducing the emergence of non-reduced (2n) embryo sacs in the ovule nucellus and the development of embryos by parthenogenesis.
Carolina Colono +9 more
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Viruses, 2019 The L-protein of vesicular stomatitis virus (VSV) is a single-chain multi-domain RNA-dependent RNA polymerase. Previously reported attempts of intramolecular insertions of fluorescent proteins into the L-protein resulted in temperature-sensitive and ...
Emmanuel Heilmann +7 more
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Molecular Origins of Functional Diversity in Benzylisoquinoline Alkaloid Methyltransferases
Frontiers in Plant Science, 2019 O- and N-methylations are ubiquitous and recurring features in the biosynthesis of many specialized metabolites. Accordingly, the methyltransferase (MT) enzymes catalyzing these modifications are directly responsible for a substantial fraction of the ...
Jeremy S. Morris, Peter J. Facchini
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