Epigenome analysis of an algae-infecting giant virus reveals a unique methylation motif catalogue. [PDF]
Truchon AR, Zinser ER, Wilhelm SW.
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G1405 Ribosomal Methyltransferase-Driven Antibacterial Resistance Affects the 4,5-Disubstituted-2-deoxystreptamine Class of Aminoglycoside Antibiotics. [PDF]
Hobbie SN +3 more
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METTL16-m<sup>6</sup>A-PGC-1α axis contributes to exercise-induced mitochondrial adaptations in skeletal muscle of high-fat diet-fed insulin-resistant mice. [PDF]
Chen C +10 more
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The 5' Cap Epitranscriptome and Beyond: Natural and Engineered 5' Cap Modifications for Optimizing mRNA Therapeutics and Functional Studies. [PDF]
Dahm GC +3 more
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Re-engineering a transferase scaffold for indole C3 methylation in diketopiperazines. [PDF]
Haase M, Weiergräber OH, Pietruszka J.
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The molecular mechanisms and potential therapeutic implications of the crosstalk between DNA methylation and metabolic reprogramming in thyroid cancer. [PDF]
Zhang T +6 more
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The supernatant fraction of liver homogenate brings about the methylation of glycine by S-adenosylmethionine. The secondary amine formed in the reaction appears to be sarcosine. This conclusion is based on (I) the stoichiometry of the reaction, and (II) radioautography of chromatograms of the incubation products. The enzyme, glycine N-methyltransferase,
J, BLUMENSTEIN, G R, WILLIAMS
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Mammals have long been known to tag their DNA by the addition of methyl groups to cytosine residues. Only quite recently, however, has the functional significance of DNA methylation established a firm footing. Evidence now indicates that DNA methylation is essential for development, and is involved in both programmed and ectopic gene inactivation ...
T H, Bestor, G L, Verdine
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