Results 81 to 90 of about 99,483 (189)

Uncovering the protein lysine and arginine methylation network in Arabidopsis chloroplasts. [PDF]

PLoS ONE, 2014
Post-translational modification of proteins by the addition of methyl groups to the side chains of Lys and Arg residues is proposed to play important roles in many cellular processes.
Claude Alban, Marianne Tardif, Morgane Mininno, Sabine Brugière, Annabelle Gilgen, Sheng Ma, Meryl Mazzoleni, Océane Gigarel, Jacqueline Martin-Laffon, Myriam Ferro, Stéphane Ravanel   +10 more
doaj   +1 more source

Geminivirus Rep Protein Interferes with the Plant DNA Methylation Machinery and Modifies the Host Epigenome [PDF]

, 2016
The apparent simplicity of viruses hides the complexity of their interactions with their hosts. Viruses are masters at circumventing host defenses and manipulating the cellular environment for their own benefit.
Castillo-Garriga, Araceli
core  

CRISPR–Cas9 Gene Editing: Curing Genetic Diseases by Inherited Epigenetic Modifications

Global Medical Genetics
Introduction CRISPR–Cas9 gene editing, leveraging bacterial defense mechanisms, offers precise DNA modifications, holding promise in curing genetic diseases.
Nikhil Deep Kolanu
doaj   +1 more source

The activity of a yeast Family 16 methyltransferase, Efm2, is affected by a conserved tryptophan and its N‐terminal region

FEBS Open Bio, 2016
The Family 16 methyltransferases are a group of eukaryotic nonhistone protein methyltransferases. Sixteen of these have recently been described in yeast and human, but little is known about their sequence and structural features.
Joshua J. Hamey, Gene Hart‐Smith, Melissa A. Erce, Marc R. Wilkins   +3 more
doaj   +1 more source

A Systematic Approach to Identifying Protein-Ligand Binding Profiles on a Proteome Scale [PDF]

, 2008
Identification of protein-ligand interaction networks on a proteome scale is crucial to address a wide range of biological problems such as correlating molecular functions to physiological processes and designing safe and efficient therapeutics.
Lei Xie, Li Xie, Nancy Buchmeier, Philip Bourne   +3 more
core   +2 more sources

Temporal and spatial expression of genes involved in DNA methylation during reproductive development of sexual and apomictic Eragrostis curvula [PDF]

, 2017
Recent reports in model plant species have highlighted a role for DNA methylation pathways in the regulation of the somatic-to-reproductive transition in the ovule, suggesting that apomixis (asexual reproduction through seeds) likely relies on RdDM ...
Echenique, Carmen Viviana, Garbus, Ingrid, Leblanc, O., Ortiz, Juan Pablo Amelio, Pessino, Silvina Claudia, Rodrigo, Juan Manuel, Romero, José Rodolfo, Selva, Juan Pablo, Siena, Lorena Adelina, Zappacosta, Diego Carlos   +9 more
core   +1 more source

Identification of RNA: 5-Methylcytosine Methyltransferases-Related Signature for Predicting Prognosis in Glioma

Frontiers in Oncology, 2020
Background: Glioma is the most common primary intracranial tumor, accounting for the vast majority of intracranial malignant tumors. Aberrant expression of RNA:5-methylcytosine(m5C) methyltransferases have recently been the focus of research relating to ...
Peng Wang, Miaojing Wu, Zewei Tu, Zewei Tu, Zewei Tu, Chuming Tao, Chuming Tao, Qing Hu, Qing Hu, Kuangxun Li, Xingen Zhu, Kai Huang, Kai Huang   +12 more
doaj   +1 more source

Plant-RRBS, a bisulfite and next-generation sequencing-based methylome profiling method enriching for coverage of cytosine positions [PDF]

, 2017
Background: Cytosine methylation in plant genomes is important for the regulation of gene transcription and transposon activity. Genome-wide methylomes are studied upon mutation of the DNA methyltransferases, adaptation to environmental stresses or ...
A Akalin, A Meissner, A Verkest, AJ Bewick, AR Elhamamsy, AR Quinlan, B Langmead, Bram Slabbinck, C Becker, CA Ibarra, Cindy Martens, D Meng, D Pignatta, EJ Finnegan, F Johannes, Frederik Coppens, G Gremme, H Parkinson, H Saze, H Schöb, H Stroud, H Zhang, H-Q Wang, HJ Xie, International Rice Genome Sequencing Project, J Du, J Yu, JI Gent, K Manning, K Okonechnikov, M Block De, M Block De, M Choi, M Hauben, M Schmidt, Magdalena Woloszynska, Marc De Block, Martin Schmidt, MD Schultz, MG Murray, Michiel Van Bel, Mieke Van Lijsebettens, P Cubas, PF Gugger, PS Schnable, R Lister, RJ Schmitz, SE Jacobsen, SJ Cokus, T-F Hsieh, The Arabidopsis Genome Initiative, TJ Treangen, TP Gurp van, W Guo, X Cao, X Chen, X Li, X Wang, X Zhang, ZD Smith, ZL Liu   +60 more
core   +3 more sources

Research Progress on the Role of Epigenetic Methylation Modification in Hepatocellular Carcinoma

Journal of Hepatocellular Carcinoma
Jing Wang,1 Wenyue Gao,1 Hongbo Yu,1 Yuting Xu,1 Changchuan Bai,2 Qingwei Cong,1 Ying Zhu1 1Infectious Department, the First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116000, People’s Republic of China; 2Internal Department of ...
Wang J, Gao W, Yu H, Xu Y, Bai C, Cong Q, Zhu Y   +6 more
doaj  

Phylogeny, expression patterns and regulation of DNA Methyltransferases in early development of the flatfish, Solea senegalensis [PDF]

, 2017
Background: The identification of DNA methyltransferases (Dnmt) expression patterns during development and their regulation is important to understand the epigenetic mechanisms that modulate larval plasticity in marine fish.
Armesto, Paula, Campinho, Marco António, Carballo, Carlos, Firmino, Joana, Manchado, Manuel, Power, Deborah M.   +5 more
core   +2 more sources