Results 51 to 60 of about 2,934 (153)

Cluster Headache and Its Cousins: A Family of Pain Management Problems

Pain Research and Management, 2000
Cluster headache causes great misery because of the severity, frequency and repetitiveness of its attacks, and the fear (justified in a few sufferers) that the attacks will respond to nothing and will never cease.
John Edmeads
doaj   +1 more source

Risks for animal health related to the presence of ergot alkaloids in feed

EFSA Journal, Volume 22, Issue 1, January 2024.
Abstract The European Commission requested EFSA to provide an update of the 2012 Scientific Opinion of the Panel on Contaminants in the Food Chain (CONTAM) on the risks for animal health related to the presence of ergot alkaloids (EAs) in feed. EAs are produced by several fungi of the Claviceps and Epichloë genera.
EFSA Panel on Contaminants in the Food Chain (CONTAM), Dieter Schrenk, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Jesús del Mazo, Bettina Grasl‐Kraupp, Christer Hogstrand, Jean‐Charles Leblanc, Carlo Stefano Nebbia, Elsa Nielsen, Evangelia Ntzani, Annette Petersen, Salomon Sand, Tanja Schwerdtle, Christiane Vleminckx, Heather Wallace, Jürgen Gropp, Patrick Mulder, Isabelle P. Oswald, Ruud Woutersen, Jose Ángel Gómez Ruiz, Elena Rovesti, Laurentius (Ron) Hoogenboom   +23 more
wiley   +1 more source

Efficacy and tolerability of intravenous methylergonovine in migraine female patients attending the emergency department: a pilot open-label study

Head & Face Medicine, 2009
Background Methylergonovine is an ergot alkaloid widely used in postpartum women. It is also an active metabolite of methysergide and previous studies suggest that it could be effective against refractory headache and cluster headache. The purpose of the
Rico-Villademoros Fernando, Mercado-Bochero Wilfrido, Caballero-García Gary, Niño-Maldonado Alfredo I, Calandre Elena P   +4 more
doaj   +1 more source

Antinociceptive Action of Moringa peregrina is Mediated by an Interaction with α2-Adrenergic Receptor

Balkan Medical Journal, 2020
Background: Moringa peregrina (M. peregrina) is an edible, drought-resistant tree that is native to semi-arid countries. It is used as a painkiller in folk medicine. Aims: To study the antinociceptive effects of the leaf extract of M. peregrina in mice.
Sahar M. Jaffal, Belal O. Al-Najjar, Manal A. Abbas, Sawsan A. Oran   +3 more
doaj   +1 more source

Pre-injury administration of morphine prevents development of neuropathic hyperalgesia through activation of descending monoaminergic mechanisms in the spinal cord in mice

Molecular Pain, 2005
The present study examined whether pre-injury administration of morphine can prevent partial sciatic nerve injury-induced neuropathic pain in mice. We observed that pre-injury administration of subcutaneous (s.c.) and intracerebroventricular (i.c.v ...
Rashid Md Harunor, Ueda Hiroshi
doaj   +1 more source

Antinociceptive Effect of Single Components Isolated from Agrimonia pilosa Ledeb. Extract

Scientia Pharmaceutica, 2019
Agrimonia pilosa Ledeb. produces an antinociceptive effect in ICR mice in both chemically induced and thermal pain models. In the present study, we examined the antinociceptive effects of single components isolated from Agrimonia pilosa Ledeb.
Jing Hui Feng, Hee Jung Lee, Set Byeol Kim, Jeon Sub Jung, Soon Sung Lim, Hong Won Suh   +5 more
doaj   +1 more source

Cluster headache

Orphanet Journal of Rare Diseases, 2008
Cluster headache (CH) is a primary headache disease characterized by recurrent short-lasting attacks (15 to 180 minutes) of excruciating unilateral periorbital pain accompanied by ipsilateral autonomic signs (lacrimation, nasal congestion, ptosis, miosis,
Ducros Anne, Leroux Elizabeth
doaj   +1 more source

5-hydroxyindolacetic acid (5-HIAA), a main metabolite of serotonin, is responsible for complete Freund's adjuvant-induced thermal hyperalgesia in mice

Molecular Pain, 2011
Background The role of serotonin (5-hydroxytrptamine, 5-HT) in the modulation of pain has been widely studied. Previous work led to the hypothesis that 5-hydroxyindolacetic acid (5-HIAA), a main metabolite of serotonin, might by itself influence pain ...
Moessner Rainald, Gerlach Manfred, Lesch Klaus-Peter, Palm Florian, Chen Yong, Sommer Claudia   +5 more
doaj   +1 more source

The pharmacological profile of ovalbumin-induced paw oedema in rats

Mediators of Inflammation, 2002
Rats are commonly used in anaphylaxis models, mainly in intestinal anaphylaxis. Hypersensitivity mechanisms are complex and they are not clearly defined. Ovalbumin (OVA) is commonly used for studies on the hypersensitivity mechanism.
R. F. G. Feitosa, G. B. Melcíades, A. M. S. Assreuy, M. F. G. Rocha, R. A. Ribeiro, A. A. M. Lima   +5 more
doaj   +1 more source

Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A2: activation of endogenous phospholipases contributes to the pronociceptive effect

Journal of Venomous Animals and Toxins including Tropical Diseases, 2017
Background Arthritis is a set of inflammatory conditions that induce aching, stiffness, swelling, pain and may cause functional disability with severe consequences to the patient’s lives.
Renata Gonçalves Dias, Sandra Coccuzzo Sampaio, Morena Brazil Sant’Anna, Fernando Queiroz Cunha, José María Gutiérrez, Bruno Lomonte, Yara Cury, Gisele Picolo   +7 more
doaj   +1 more source