Results 81 to 90 of about 13,572 (204)
Hyper-IgD syndrome or mevalonate kinase deficiency.
, 2011 Contains fulltext : 95975.pdf (Publisher’s version ) (Closed access)PURPOSE OF REVIEW: The hyper-IgD and periodic fever syndrome (HIDS) is one of the classical monogenetic hereditary autoinflammatory disorders, and together with the ...
Stoffels, M. +3 more
core +1 more source
Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases
Journal of Periodontal Research, EarlyView.This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini +3 more
wiley +1 more source
Mevalonate kinase deficiency: Evidence for a phenotypic continuum
, 2004 Both mevalonic aciduria, characterized by psychomotor retardation, cerebellar ataxia, recurrent fever attacks, and death in early childhood, and hyper-immunoglobulin D (hyper-IgD) syndrome, with recurrent fever attacks without neurologic symptoms, are ...
Wevers, R A +6 more
core +1 more source
Mevalonate kinase deficiency leads to decreased prenylation of Rab GTPases
, 2016 Mevalonate kinase deficiency (MKD) is caused by mutations in a key enzyme of the mevalonate-cholesterol biosynthesis pathway, leading to recurrent autoinflammatory disease characterised by enhanced release of interleukin-1β (IL-1β).
Ziegler, JB +13 more
core +2 more sources
Climate change and crop resilience: harnessing metabolomics for predicting stress tolerance
New Phytologist, EarlyView.Summarised methodology for metabolite biomarker discovery and genomic targets selection for those metabolites to predict high‐throughput phenotypic and agronomic traits of interest for direct uptake in breeding programmes. Summary Global warming is driving climate change to levels not experienced since the advent of agriculture, primarily due to ...
Agyeya Pratap +3 more
wiley +1 more source
Food Frontiers, Volume 7, Issue 4, July 2026.This review analyzes single/combined abiotic (light, water, nutrients, hormones) and biotic (microbes, yeast) elicitors regulating signaling, gene expression, and metabolism to boost plant secondary metabolites. It highlights synergistic multielicitor strategies for crop quality and functional foods, while critically addressing current limitations and ...
Yifei Sun +6 more
wiley +1 more source
The Turkish Journal of Pediatrics, 2012 The hyperimmunoglobulinemia D syndrome (HIDS), so-called mevalonate kinase deficiency, is caused by recessive mutations in the gene encoding mevalonate kinase enzyme.
Pınar Gençpınar +4 more
doaj
JCC Plus, Volume 1, Issue 4, July 2026.ABSTRACT Background Low‐dose thiopurine therapy in combination with allopurinol (LD‐THIO/ALLO) is a widely used treatment for inflammatory bowel disease (IBD). However, little is known about the effects of in utero exposure to this combination on pregnancy and birth outcomes.
Kavitha Sivananthan +9 more
wiley +1 more source
Outburst of Macrophage Activation Syndrome in Mevalonate Kinase Deficiency
, 2015 A comment on the Article by Schulert et al is provided by this paper dealing with mevalonate kinase ...
Donato Rigante, Rigante, Donato
core +1 more source
Mevalonate kinase deficiency: therapeutic targets, treatments, and outcomes [PDF]
, 2017 Introduction: Mevalonate Kinase Deficiency (MKD) is a rare inborn disease caused by the mutation of mevalonate kinase gene. The clinical phenotype encompasses recurrent fever episodes in combination with gastrointestinal, immunological, rheumatological ...
MARCUZZI, ANNALISA +7 more
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