Results 71 to 80 of about 28,306 (175)

Histopathologic features in a case of hyperimmunoglobulinemia D syndrome

Indian Dermatology Online Journal, 2015
We describe a case of Mevalonate Kinase Deficiency (MKD) also known as Hyperimmunoglobulinemia D Syndrome (HIDS) presenting as a Sweet-like syndrome in a 5-week-old with multiple erythematous plaques, fever, aseptic meningitis, and bronchiolitis.
Sarah Pace, Jonathan Bingham, Michael Royer   +2 more
doaj   +1 more source

Comparative efficacy of seed biopriming and soil drenching with Bacillus altitudinis TM22 and Bacillus atrophaeus MCM61 on the suppression of Fusarium wilt of cotton

Pest Management Science, Volume 82, Issue 3, Page 2424-2445, March 2026.
Co‐application of Bacillus strains TM22 and MCM61 suppressed Fusarium wilt of cotton. Seed biopriming with Bacillus strains performed better than soil drenching. TM22 + MCM61 improved vegetative and physiological aspects in cotton plants. TM22 + MCM61 enhanced the activity of defense enzymes and defense gene expression.
Tahir Mahmood, Anam Moosa, Faisal Zulfiqar, Muhammad Naveed Aslam, Ohud Muslat Alharthy, Fatimah Hadadi, Ahmad F. Alhomodi, Seham Sater Alhelaify, Eman Fayad, Asim Alsenani, Salman Aloufi, Tolga İzgü   +11 more
wiley   +1 more source

Molecular mechanisms associated with rootstock–scion interactions in rubber trees

The Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Hevea brasiliensis (rubber tree) is the main source of natural rubber worldwide. In commercial plantations, high‐yield rubber tree clones are propagated by grafting onto seedling rootstocks. In this study, the transcriptomes of the RRIM 600 clone grafted on different rootstocks in southeastern Brazil were evaluated. Exclusively expressed genes
Wanderson Lima Cunha, Vinicius Mandolesi Rios, Alexandre Hild Aono, Danilo Augusto Sforça, Aline Da Costa Lima Moraes, Milene Silvestrini, Jose Marcos Dias Ferreira Junior, Antonio Lucio Mello Martins, Elaine Cristine Piffer Gonçalves, Paulo de Souza Gonçalves, Felipe Roberto Francisco, Anete Pereira de Souza   +11 more
wiley   +1 more source

Metabolomic and Single‐Cell Transcriptomic Analyses Shed Light on Secondary Metabolite Profiling and Potential Developmental Dynamics of Glandular Trichomes in Artemisia argyi

Plant Biotechnology Journal, Volume 24, Issue 3, Page 1064-1081, March 2026.
ABSTRACT Plant glandular trichomes (GTs) are characterised by their ability to synthesise and store abundant secondary metabolites of significant biological importance. The medicinal plant Artemisia argyi exhibits a dense covering of GTs, yet the precise metabolic compositions and the developmental molecular dynamics of A.
Shuting Dong, Hongyu Chen, Sijie Sun, Miaoxian Guo, Chao Sun, Shilin Chen, Hongmei Luo   +6 more
wiley   +1 more source

Mevalonate kinase deficiency (hyper IgD syndrome with periodic fever)--different faces with separate treatments: two cases and review of the literature

The Turkish Journal of Pediatrics, 2012
The hyperimmunoglobulinemia D syndrome (HIDS), so-called mevalonate kinase deficiency, is caused by recessive mutations in the gene encoding mevalonate kinase enzyme.
Pınar Gençpınar, Balahan B Makay, Marco Gattorno, Francesco Caroli, Erbil Ünsal   +4 more
doaj  

ZmTH1 Is Vital for Healthy Plant Growth and Promotes Cold/Drought Tolerance by Regulating Thiamin Diphosphate‐Dependent Metabolisms in Maize

Plant Biotechnology Journal, Volume 24, Issue 3, Page 1234-1250, March 2026.
ABSTRACT Vitamin B1 (VB1) plays a crucial role in sustaining plant health and enabling adaptive responses to environmental stress. The complex maize genome implies a sophisticated VB1 synthesis pathway, with the mechanisms by which VB1 benefits plants remaining elusive.
Tengfei Zhang, Jie Zang, Boming Yang, Qiuxia Wang, Jijun Yan, Peiyong Xin, Jinfang Chu, Huabang Chen, Zhaogui Zhang   +8 more
wiley   +1 more source

Heterologous Production of Forskolin in Tobacco (Nicotiana tabacum) via Glandular Trichome Specific Engineering and Metabolic Flux Redirection

Plant Biotechnology Journal, Volume 24, Issue 3, Page 1548-1563, March 2026.
ABSTRACT Plants are promising bioreactor for the sustainable and scalable production of high‐value natural bioactive compounds, because they can synthesise phytochemicals from CO2, light, water and minerals through their innate photosynthetic carbon assimilation machinery.
Xuan Sun, Xiuming Wu, Xun Jiang, Hongmei Huang, Aiguo Yang, Yiting Li, Zhenjun Fan, Aixia Chang, Changqing Yang   +8 more
wiley   +1 more source

The laboratory approach in the diagnosis of systemic autoinflammatory diseases

Reumatismo, 2011
Systemic autoinflammatory diseases are a group of inherited disorders of the innate immunity characterized by the recurrence of febrile attacks lasting from few hours to few weeks and multi-district inflammation of different severity involving skin ...
B. Frediani, M. Galeazzi, O.M. Lucherini, G.D. Sebastiani, D. Rigante, M.G. Brizi, L. Cantarini   +6 more
doaj   +1 more source

Modulation of Network Plasticity Opens Novel Therapeutic Possibilities in Cancer, Diabetes, and Neurodegeneration

Advanced Science, Volume 13, Issue 12, 27 February 2026.
Plasticity changes of molecular networks form a cellular learning process. Signaling network plasticity promotes cancer, metastasis, and drug resistance development. 55 plasticity‐related cancer drug targets are listed (20 having already approved drugs, 9 investigational drugs, and 26 being drug target candidates).
Márk Kerestély, István Narozsny, Levente Szarka, Daniel V. Veres, Peter Csermely, Dávid Keresztes   +5 more
wiley   +1 more source

Mevalonate kinase-deficient THP-1 cells show a disease-characteristic pro-inflammatory phenotype

Frontiers in Immunology
ObjectiveBi-allelic pathogenic variants in the MVK gene, which encodes mevalonate kinase (MK), an essential enzyme in isoprenoid biosynthesis, cause the autoinflammatory metabolic disorder mevalonate kinase deficiency (MKD).
Frouwkje A. Politiek, Frouwkje A. Politiek, Marjolein Turkenburg, Rob Ofman, Hans R. Waterham, Hans R. Waterham, Hans R. Waterham   +6 more
doaj   +1 more source