Results 101 to 110 of about 10,880 (220)
Quantitation of plasma mevalonic acid using gas chromatography-electron capture mass spectrometry.
Journal of Lipid Research, 1991 Circulating concentrations of mevalonic acid (MVA) change in parallel with, and may be used as a marker of cholesterol biosynthesis. Plasma MVA levels have been quantified using a sensitive and specific capillary gas chromatography-electron capture mass ...
A Scoppola +4 more
doaj +1 more source
HMG-CoA reductase is not the site of the primary defect in phytosterolemia
Journal of Lipid Research, 1998 Phytosterolemia is an autosomal recessive disorder characterized by the excessive absorption, reduced excretion, and consequent high tissue and plasma levels of plant sterols, by the presence of tendon xanthomas, and by premature atherosclerosis. Low HMG-
G.M.B. Berger +9 more
doaj +1 more source
The 4G/5G PAI-1 polymorphism influences the endothelial response to IL-1 and the modulatory effect of pravastatin [PDF]
, 2006 BACKGROUND: Increased plasminogen activator inhibitor (PAI-1) levels lead to impaired fibrinolytic function associated with higher cardiovascular risk. PAI-1 expression may be regulated by different inflammatory cytokines such as interleukin-1alpha (IL-1)
Belzunce, M. (Miriam) +4 more
core
Analysis and enhancement of astaxanthin accumulation in Haematococcus pluvialis [PDF]
, 2005 The green microalga Haematococcus pluvialis was cultured with different concentrations of NaNO3 to determine the effect on cell growth and astaxanthin accumulation.
Abalde, Julio +3 more
core +2 more sources
Медицинская иммунология, 2014 . The effects of cholesterol (Ch) diet, i.p. administration of mevalonic acid (Mev) and their combined application upon nitric oxide (NO) production in peritoneal macrophages, as well as upon biochemical characteristics of kidney function derangements ...
Ya. Sh. Schwarz +3 more
doaj +1 more source
Biotropia: The Southeast Asian Journal of Tropical Biology, 2003 Effect on callus growth was studied for Citrus grandis cultured with feeding of exogenous mevalonic acid (MVA) at concentrations of 0.04, 0.08, 0.38, 0.77, 1.15 and 1.54 mM.
ZARINA ZAKARiA +2 more
doaj
Origin of esterified cholesterol transported in the very low density lipoproteins of human plasma
Journal of Lipid Research, 1974 In two subjects the specific activity of esterified cholesterol in plasma lipoprotein subfractions was measured for up to 9 hr after an intravenous injection of [3H]mevalonic acid.
Philip J. Barter
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The role of circulating mevalonate in nephrotic hypercholesterolemia in the rat.
Journal of Lipid Research, 1990 The cause of the hypercholesterolemia that characterizes the nephrotic syndrome has never been adequately explained. The present study examines the possibility that enhanced availability of the cholesterol precursor, mevalonic acid, to the liver in the ...
T A Golper +3 more
doaj +1 more source
, 2016 古来より紫色素は洋の東西を問わず高貴な色として尊ばれてきた｡本稿では東洋とﾖｰﾛｯﾊﾟで主に流通しているﾑﾗｻｷ科植物を取り上げて基原植物や歴史的な背景を検証した｡特にﾑﾗｻｷは日本における自生分布が広く､8～10世紀には各地で栽培が行われ大量の紫根が朝廷へ上納されていた状況について述べた｡紫根に含有する紫色素である shikonin は日本で単離構造決定されたのでそれらに付いても言及した｡さらにﾑﾗｻｷ科植物の shikonin や光学異性体の alkannin 等の生合成経路についても述べた｡又 ...
Yukihiro SHOYAMA, 正山 征洋
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Short, Enantioselective Synthesis of Mevalonic Acid
A new enantioselective synthesis of mevalonic acid that is short, flexible, scalable to gram amounts, and uses readily available starting materials is reported. Enantioselective homoallylic epoxidation of isoprenol followed by enantiomeric enrichment gave the key epoxide intermediate.
Ryan J. Oconnell +3 more
openaire +1 more source