Results 31 to 40 of about 562 (137)

Cardioprotective efficiency study of combination of pyrimidine and 3-hydroxypyridine derivatives in experimental antitumor chemotherapy [PDF]

open access: yesСаратовский научно-медицинский журнал, 2014
The aim of the study is to analyze the influence of combination of pyrimidine and 3-hydroxypyridine derivatives — xymedon and mexidol, in comparison with kardioxane on the myocardial bioelectric activity and arterial pressure level in rats with Walker ...
Siprov A.V., Kostina Yu.A.
doaj  

The effect of 60-day administration of sodium benzoate and mexidol on the ultrastructure of the regenerate formed in the rat's tibiae [PDF]

open access: yes, 2023
The aim was to study the possibility of correction of changes in the ultrastructure of the rat's tibiae regenerate caused by 60-day administration of sodium benzoate with mexidol by using the X-ray diffraction ...
Luzin, V., Morozov, V.
core  

MORPHOMETRIC PULMONIC INDICATORS USING MEXIDOL IN RATS WITH EXPERIMENTAL ACUTE RESPIRATORY DISTRESS SYNDROME

open access: yesИзвестия высших учебных заведений. Поволжский регион: Медицинские науки, 2020
Background. The purpose of this work is to evaluate the effectiveness of Mexidol on the degree of development of acute respiratory distress syndrome (ARDS) by morphometric parameters of lung tissue. Matherials and Methods.
G. G. Makiev   +3 more
doaj   +1 more source

Chronic Lead Exposure and Tauopathies: Molecular Mechanisms of Neurotoxicity and Emerging Nanotherapeutic Strategies

open access: yesJournal of Toxicology, Volume 2026, Issue 1, 2026.
Chronic exposure to lead (Pb) remains a critical global public health challenge, extending beyond its established neurotoxic effects to its emerging role in the pathogenesis of neurodegenerative disorders, particularly tauopathies. Accumulating evidence indicates that prolonged Pb exposure disrupts neuronal homeostasis through multiple interconnected ...
Maryam Ebrahimi   +3 more
wiley   +1 more source

TEST SYSTEM FOR EVALUATION OF THE INFLUENCE OF THE BIOLOGICAL ACTIVITY OF SUBSTANCES ON THE SIGNAL SYSTEM OF NF-κB: FOCUS ON THE DERIVATIVES OF 3-HYDROXYPYRIDINE [PDF]

open access: yesResearch Results in Pharmacology, 2017
Introduction: The nuclear factor kappa B is one of the most promising targets for the development of innovative medicines in the development of modern pharmacology and the formation of the concept of targeted therapy.
Sophiya Ya. Skachilova   +3 more
doaj   +3 more sources

Myeloprotective efficiency of combination of pyrimidine and 3-hydroxypyridine derivatives in experimental antineoplastic chemotherapy [PDF]

open access: yesСаратовский научно-медицинский журнал, 2015
The aim of the study is comparative assessment of the influence of separated and combined use of pyrimidine and 3-hydroxypyridine derivatives — xymedon and mexidol on the bone marrow hemopoiesis and peripheral blood quantitative indicators in rats with ...
Siprov A.V., Masyagin V.A.
doaj  

Interaction of erythrocyte membranes with derivatives of 3-oxypiridines

open access: yesActa Biomedica Scientifica, 2017
In connection with the increased interest in the use of auto-erythrocytes for directional drug transport, the study of the ability of erythrocytes to sorb an antioxidant drug is becoming topical.
E. E. Kuznetsova   +4 more
doaj   +1 more source

Voltammetric determination of mexidol

open access: yes, 2020
A new voltammetric method for determining mexidol in pharmaceuticals is proposed. Using this technique, mexidol was determined in model solutions (with RS = of 1-6%) and in a ready-to-use preparation. The analytical range of mexidol determination using a
Budnikov G., Ziyatdinova G.
core  

CLINICAL ASPECTS OF ETHYLMETHYLHYDROXYPYRIDINE SUCCINATE IN ELDERLY PATIENTS WITH CARDIOVASCULAR PATHOLOGY

open access: yesКардиоваскулярная терапия и профилактика, 2018
Aim. To evaluate efficacy and safety of original ethylmethylhydroxypyridine succinate (Mexidol) in cardiological patients ≥75 year old.Material and methods.
E. G. Martemianova
doaj   +1 more source

CORRECTION OF THROMBOCYTOPOIESIS IN RATS WITH WALKER-256 CARCINOMA USING AN ANTIOXIDANT SUPPLEMENT IN THE SETTING OF CYTOSTATICS

open access: yes, 2021
In this study, we've evaluated the myelotoxic effect of treating Walker-256 carcinoma with cytostatics, followed by correction of thrombocytopenia with liposomal and liposome-free mexidol.
Gvozdikova E.   +16 more
core   +1 more source

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