Results 21 to 30 of about 249 (164)

Effect of mexidol on lipid-phospholipid profile changes in elderly patients with stroke

open access: yesНеврология, нейропсихиатрия, психосоматика, 2018
Objective: to evaluate the efficiency of incorporating of mexidol into combination drug therapy for elderly patients with acute ischemic and hemorrhagic stroke (IS and HS). Patients and methods.
Yu. V. Abramenko
doaj   +1 more source

Interaction of erythrocyte membranes with derivatives of 3-oxypiridines

open access: yesActa Biomedica Scientifica, 2017
In connection with the increased interest in the use of auto-erythrocytes for directional drug transport, the study of the ability of erythrocytes to sorb an antioxidant drug is becoming topical.
E. E. Kuznetsova   +4 more
doaj   +1 more source

Myeloprotective efficiency of combination of pyrimidine and 3-hydroxypyridine derivatives in experimental antineoplastic chemotherapy [PDF]

open access: yesСаратовский научно-медицинский журнал, 2015
The aim of the study is comparative assessment of the influence of separated and combined use of pyrimidine and 3-hydroxypyridine derivatives — xymedon and mexidol on the bone marrow hemopoiesis and peripheral blood quantitative indicators in rats with ...
Siprov A.V., Masyagin V.A.
doaj  

Glutathione content in erythrocytes and bone marrow of animals in mexidol use under the conditions of acute stress

open access: yesZaporožskij Medicinskij Žurnal, 2013
Acute immobilization stress and its pharmacological correction with mexidol (2-ethyl-6-methyl-3-oxypyridine succinate) were modeled in albino male rats.
N. O. Vlasenko
doaj   +1 more source

CLINICAL ASPECTS OF ETHYLMETHYLHYDROXYPYRIDINE SUCCINATE IN ELDERLY PATIENTS WITH CARDIOVASCULAR PATHOLOGY

open access: yesКардиоваскулярная терапия и профилактика, 2018
Aim. To evaluate efficacy and safety of original ethylmethylhydroxypyridine succinate (Mexidol) in cardiological patients ≥75 year old.Material and methods.
E. G. Martemianova
doaj   +1 more source

Effect of the 60-day introduction of tartrazine and mexidol on the ultrastructure of the rat’s parathyroid gland chief cells

open access: yesИзвестия высших учебных заведений. Поволжский регион: Медицинские науки, 2023
Background. The purpose was to study the effect of long-term administration of tartrazine and mexidol on the ultramicroscopic structure of the chief cells of the parathyroid glands in rats. Materials and methods.
V.I. Luzin, V.N. Morozov
doaj   +1 more source

Treatment of vertigo in elderly patients with chronic cerebrovascular disease

open access: yesНеврология, нейропсихиатрия, психосоматика, 2018
Dizziness can be caused by different problems in elderly patients; the possibilities of drug therapy are limited; betahistine dihydrochloride is most commonly used.Objective: to investigate the efficiency and safety of combination therapy with mexidol ...
S. N. Duma
doaj   +1 more source

Comparative evaluation of antioxidant drug influence on a radio therapy efficiency and oxidative status in mice

open access: yesRussian Open Medical Journal, 2013
The aim of the study is a comparative analysis of the effect of melatonin (Melaxen) and 3-hydroxypyridine (Mexidol) on antitumor and antimetastatic influence of chemoradiotherapy and oxidative status at mice with Lewis lung carcinoma.
Alexander V. Siprov   +2 more
doaj  

Effect of the combination of mexidol and diclofenac sodium on exudative inflammation in rats after ten-day preventive oral administration

open access: yesФармакокинетика и Фармакодинамика, 2022
In rats with carrageenan-induced paw edema, diclofenac sodium significantly reduces exudation after ten-day preventive oral administration at a dose of 10 mg/kg but not 5 mg/kg.
E. A. Ivanova   +3 more
doaj   +1 more source

CREATION AND PHARMACOTECHNOLOGICAL INVESTIGATIONS OF INNOVATIVE DOSAGE FORMS OF MEXIDOL

open access: yesРазработка и регистрация лекарственных средств, 2019
The present study is devoted to the creation and study of transdermal dosage forms with mexidol and experimental substantiation of their therapeutic efficacy.
E. F. Stepanova   +2 more
doaj  

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