Results 1 to 10 of about 562 (137)

Effect of Mexidol on Lipid-Phospholipid Profile Changes in Elderly Patients With Stroke [PDF]

open access: yesNevrologiya, Neiropsikhiatriya, Psikhosomatika, 2018
Objective: to evaluate the efficiency of incorporating of mexidol into combination drug therapy for elderly patients with acute ischemic and hemorrhagic stroke (IS and HS). Patients and methods.
Yu. V. Abramenko
exaly   +4 more sources

The study of the endothelial protective properties of the L-norvaline combination with mexidol in the simulation of L-NAME-induced NO deficiency [PDF]

open access: yesResearch Results in Pharmacology, 2019
Introduction: The endothelium is considered as a target for the prevention and treatment of pathological processes leading to cardiovascular diseases. Materials and methods: Endothelial dysfunction was simulated in male rats using an e-
Elena A. Konovalova   +1 more
doaj   +6 more sources

Coorection Of Lipid Peroxydation And Antioxydant Protective System By Mexidol And Glycine In Patients With Acute Ethanol Intoxication [PDF]

open access: yesСаратовский научно-медицинский журнал, 2009
The research goal is to study lipid peroxydation and ferments of antioxidant protection in group of patients with an acute alcohol intoxication and their correction by medicaments with antioxidant activity (mexidol, glycine and their combination ...
R.S. Farshatov   +2 more
doaj   +2 more sources

Safety of Mexidol® (Ethylmethylhydroxypyridine Succinate) in Adult Patients of Different Age Groups

open access: yesNevrologiya, Neiropsikhiatriya, Psikhosomatika, 2022
To reduce the risk of developing adverse events (AEs) and increase the adherence of elderly patients to treatment, it is recommended to limit maximally the total number of prescribed drugs (DR), using one drug for the treatment of two or more pathologies
Elena Ushkalova   +2 more
exaly   +3 more sources

Effect of multiple-dose regimens of cyclooxygenase inhibitors and their combinations with mexidol on behavior in mature rats [PDF]

open access: yesФармакокинетика и Фармакодинамика, 2023
Effects of multiple-dose regimens (oral, daily, once a day for 15 days) of cyclooxygenase (COX) inhibitors etoricoxib (1 and 10 mg/kg), diclofenac sodium (1 and 5 mg/kg) and their combinations with 2-ethyl-6-methyl-3-hydroxypyridine succinate (mexidol 25
E. A. Ivanova   +3 more
doaj   +2 more sources

Theoretical Insights Into the Antiradical Activity and Copper-Catalysed Oxidative Damage of Mexidol in the Physiological Environment

open access: yesRoyal Society Open Science, 2022
Mexidol (MD, 2-ethyl-6-methyl-3-hydroxypyridine) is a registered therapeutic agent for the treatment of anxiety disorders. The chemical structure suggests that MD may also act as an antioxidant. In this study, the hydroperoxyl radical scavenging activity
Quan V Vo, Adam Mechler, Bay Mai Van
exaly   +3 more sources

The efficacy and safety of ethyl methyl hydroxypyridine succinate used as part of sequential therapy in patients with chronic cerebral ischemia [PDF]

open access: yesНеврология, нейропсихиатрия, психосоматика, 2020
Objective: to investigate the efficacy and safety of Mexidol® FORTE 250 in patients with chronic cerebral ischemia (CCI) in the presence of hypertension and atherosclerosis.Patients and methods.
V. V. Burdakov, D. V. Krasnykh
doaj   +2 more sources

THE IMPORTANCE OF A PHOTOSENSITIZER BLEACHING REGISTRATION FOR THE EVALUATION OF MECHANISM OF PREPARATION ACTION ON THE PHOTO-INDUCED HEMOLYSIS [PDF]

open access: yesBiomedical Photonics, 2017
The influence of three pharmaceutical preparations on photo-induced lysis (irradiation with light-emitting diode of 653 nm) of human erythrocytes in the presence of photosensitizer radachlorin and also on the quantum yield of radachlorin photobleaching ...
L. V. Galebskaya   +7 more
doaj   +4 more sources

Possibilities of multimodal neuroprotection in patients with chronic cerebral ischemia on the background of arterial hypertension and atherosclerosis

open access: yesНеврология, нейропсихиатрия, психосоматика, 2023
hronic cerebrovascular pathology is manifested by a combination of cognitive, emotional and autonomic disorders. Correct and timely assessment and accurate diagnosis of emotional and autonomic disorders and their timely correction are important, among ...
I. A. Gribacheva   +3 more
doaj   +1 more source

Potential of a palladium–Mexidol complex in normalization of liver tests as a dual organoprotective of hepato-renal function in a paracetamol-induced rat model [PDF]

open access: yesJournal of Nephropharmacology
Introduction: Paracetamol overdose is a primary cause of acute liver and renal damage due to oxidative stress and depletion of glutathione reserves.
Fuad Yusir Mammadov   +6 more
doaj   +1 more source

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