Results 11 to 20 of about 249 (164)

Effect of multiple-dose regimens of cyclooxygenase inhibitors and their combinations with mexidol on behavior in mature rats

Фармакокинетика и Фармакодинамика, 2023
Effects of multiple-dose regimens (oral, daily, once a day for 15 days) of cyclooxygenase (COX) inhibitors etoricoxib (1 and 10 mg/kg), diclofenac sodium (1 and 5 mg/kg) and their combinations with 2-ethyl-6-methyl-3-hydroxypyridine succinate (mexidol 25
E. A. Ivanova, A. G. Vasilchuk, A. I. Matyushkin, T. A. Voronina   +3 more
doaj   +1 more source

The effect of Mexidol on magnesium-calcium balance and endothelial dysfunction in operational stress [PDF]

Саратовский научно-медицинский журнал, 2014
The aim of the study: to study the effect of mexidol content of ionized calcium and magnesium in erythrocytes and the number of circulating endothelial cells in patients undergoing surgery in the maxillofacial area. Material and methods.
Baturin V.A., Fisher V.V., Sergeev S.A., Yatsuk I.V.   +3 more
doaj  

Potential of a palladium–Mexidol complex in normalization of liver tests as a dual organoprotective of hepato-renal function in a paracetamol-induced rat model [PDF]

Journal of Nephropharmacology
Introduction: Paracetamol overdose is a primary cause of acute liver and renal damage due to oxidative stress and depletion of glutathione reserves.
Fuad Yusir Mammadov, Shahzada Musa Polukhova, Zumrud Amirgulu Abaszade, Kamil Sahib Alkishiev, Hijran Faramaz Khidirova, Maryam Rauf Abbasova, Aygun Vugar Kazimli   +6 more
doaj   +1 more source

Antiamnestic effect of new nicotinic acid derivatives [PDF]

Research Results in Pharmacology, 2021
Introduction: The search for new drugs for the prevention and treatment of vascular cognitive disorders continues to be a relevant task of pharmacology.
Victor V. Yasnetsov, Diana E. Kaurova, Sofia Ya. Skachilova, Evgeniy Yu. Bersenev   +3 more
doaj   +3 more sources

MORPHOMETRIC PULMONIC INDICATORS USING MEXIDOL IN RATS WITH EXPERIMENTAL ACUTE RESPIRATORY DISTRESS SYNDROME

Известия высших учебных заведений. Поволжский регион: Медицинские науки, 2020
Background. The purpose of this work is to evaluate the effectiveness of Mexidol on the degree of development of acute respiratory distress syndrome (ARDS) by morphometric parameters of lung tissue. Matherials and Methods.
G. G. Makiev, A. E. Gurina, N. A. Gabolaeva, N. V. Sokolovskiy   +3 more
doaj   +1 more source

Cardioprotective efficiency study of combination of pyrimidine and 3-hydroxypyridine derivatives in experimental antitumor chemotherapy [PDF]

Саратовский научно-медицинский журнал, 2014
The aim of the study is to analyze the influence of combination of pyrimidine and 3-hydroxypyridine derivatives — xymedon and mexidol, in comparison with kardioxane on the myocardial bioelectric activity and arterial pressure level in rats with Walker ...
Siprov A.V., Kostina Yu.A.
doaj  

Possibilities of Using Nootropic Drugs to Reduce Neurotoxic Reactions Caused by Anti-tuberculosis Drugs in Experimental Conditions

Туберкулез и болезни лёгких
The objective: to evaluate the neuroprotective activity of cytoflavin and combinations of mexidol with vitamin B6 or Magne B6 by changes in behavioral reactions in rats during in-take of a neurotoxic combination of anti-tuberculosis drugs.Subjects and ...
G. N. Mozhokina, A. G. Samoylova, I. A. Vasilyeva   +2 more
doaj   +1 more source

Effect of mexidol on the efficiency of intravenous thrombolytic therapy for ischemic stroke during the therapeutic window

Неврология, нейропсихиатрия, психосоматика, 2018
Objective: to evaluate the effect of intravenous mexidol on the efficiency of intravenous thrombolytic therapy (TLT) during the therapeutic window. Patients and methods.
K. S. Knni, T. V. Dyomin, L. B. Adeeva
doaj   +1 more source

Effect of mexidol on physical and mental performance under stressogenic conditions in experiment

Фармакокинетика и Фармакодинамика, 2019
The effect of Mexidol on physical performance of mice under the extreme conditions of the weight-loaded forced swim test and on the mental performance of rats under the conditions of a neurosis-like state caused by a functional disturbance of a defensive
I. G. Kapitsa, E. A. Ivanova, T. A. Voronina   +2 more
doaj   +1 more source

TEST SYSTEM FOR EVALUATION OF THE INFLUENCE OF THE BIOLOGICAL ACTIVITY OF SUBSTANCES ON THE SIGNAL SYSTEM OF NF-κB: FOCUS ON THE DERIVATIVES OF 3-HYDROXYPYRIDINE [PDF]

Research Results in Pharmacology, 2017
Introduction: The nuclear factor kappa B is one of the most promising targets for the development of innovative medicines in the development of modern pharmacology and the formation of the concept of targeted therapy.
Sophiya Ya. Skachilova, Vera Ragulina, Darya Kostina, Youri Burda   +3 more
doaj   +3 more sources