Results 1 to 10 of about 7,531 (200)

Combining Intramuscular and Intranasal Immunization With the MF59‐Adjuvanted Respiratory Syncytial Virus Pre‐Fusion Protein Subunit Vaccine Induces Potent Humoral and Cellular Immune Responses in Mice [PDF]

MedComm
Respiratory syncytial virus (RSV) ranks as the second leading cause of infant death globally and a significant contributor to morbidity and mortality among adults over 60 years old.
Jie Shi, Hong Lei, Yu Zhang, Chunjun Ye, Xiya Huang, Yishan Lu, Yanyan Liu, Jian Liu, Danyi Ao, Yingqiong Zhou, Jiong Li, Guangwen Lu, Xiangrong Song, Xiawei Wei   +13 more
doaj   +3 more sources

Efficacy of Immunostimulatory Adjuvants and Nano‐Adjuvants in Current SARS‐CoV‐2 Vaccines: A Comprehensive Review [PDF]

Health Science Reports
Background and Aims SARS‐CoV‐2 continues to pose global challenges, and current vaccines face limitations (variant escape, waning immunity). This review evaluates immunostimulatory adjuvants and nano‐adjuvants to enhance immune responses and optimize ...
Peyman Kheirandish Zarandi, Mohammad Reza Zinatizadeh, Mohsen Ghiasi, Mohammad Rezaei Zadeh Rukerd, Hanieh Mirkamali, Ehsan Shokri   +5 more
doaj   +3 more sources

Safety and immunogenicity of an MF59™-adjuvanted subunit influenza vaccine in elderly Chinese subjects [PDF]

Immunity & Ageing, 2008
Background The safety and immunogenicity of an MF59™-adjuvanted subunit influenza vaccine (Sub/MF59™; FLUAD®, Novartis Vaccines) was evaluated among elderly Chinese subjects (≥ 60 years of age).
Pellegrini Michele, Liu Youping, Li Yanping, Fang Hanhua, Li Rongcheng, Podda Audino   +5 more
doaj   +3 more sources

Specificity and functional humoral immune responses induced by the VBI-1501A eVLP HCMV gB vaccine compared to the gB/MF59 vaccine [PDF]

Human Vaccines & Immunotherapeutics
Human cytomegalovirus (HCMV) is the leading infectious cause of birth defects globally yet has no licensed vaccine. Though some HCMV glycoprotein B (gB)-based vaccine candidates, such as the MF59-adjuvanted gB vaccine (gB/MF59) elicited limited virus ...
Megan R. Connors, Krithika P. Karthigeyan, Adelaide S. Fuller, Libby Mitchell, Hannah Preston, Sergey Ananyev, Chelsea M. Crooks, Richard J. Stanton, David E. Anderson, Sallie R. Permar   +9 more
doaj   +2 more sources

Enhanced immunogenicity of Staphylococcus aureus IsdE vaccine with SeNPs and BCG adjuvants in mice [PDF]

AMB Express
Staphylococcus aureus is a major cause of nosocomial infections and antimicrobial resistance, emphasizing the urgent need for an effective vaccine. The IsdE protein, a heme-iron transporter, has been identified as a promising antigen target.
Fatemeh Khosravani pour, Setareh Haghighat, Mohammad Hossein Yazdi, Seyed Mehdi Hassanzadeh   +3 more
doaj   +2 more sources

Construction and Immune Strategy Optimization of a Vaccine Strain for Influenza A (H5N8) Subtype [PDF]

Viruses
Multiple subtypes of avian influenza virus (AIV), including H5N1, H5N6, and H5N8 viruses, are currently co-circulating in wild birds and poultry and causing sporadic human infections. Vaccine development is essential for pandemic preparedness.
Shuxia Zhang, Jing Tang, Liqi Liu, Hejiang Wei, Li Xin, Kang Xiao, Jinbo Xiao, Jie Dong, Zi Li, Hongyan Bai, Shuaixing Wang, Wenfei Zhu, Lei Yang, Shumei Zou, Dayan Wang   +14 more
doaj   +2 more sources

PPD in HBsAg vaccine formulation suppressed IFN-γ and IL-4 cytokine responses and induced long-lived humoral immune responses: Results from 220-day monitoring of specific IgG responses [PDF]

Iranian Journal of Basic Medical Sciences, 2022
Objective(s): HBsAg vaccine is unable to induce Th1 immune responses. Here, immune responses and long-lived IgG responses of HBsAg-Alum, HBsAg-MF59, as well as HBsAg-MF59 were compared when formulated with PPD.
Rayhaneh Mirzaee, Fahimeh Nemati Mansoor, Mina Mirzaee, Bahareh Golkaran, Akbar Khorasani, Niloufar Rashedi, Fatemeh Asgarhalvaei, Mohammad Ali Savoji, Mehdi Mahdavi   +8 more
doaj   +1 more source

Intramuscular Immunisation with Chlamydial Proteins Induces Chlamydia trachomatis Specific Ocular Antibodies. [PDF]

, 2015
BACKGROUND: Ocular infection with Chlamydia trachomatis can cause trachoma, which is the leading cause of blindness due to infection worldwide. Despite the large-scale implementation of trachoma control programmes in the majority of countries where ...
Badamchi-Zadeh, A, Brzozowski, A, Follmann, F, Holland, MJ, Lacey, C, McKay, PF, Paes, W, Shattock, RJ, Tregoning, JS   +8 more
core   +18 more sources

Comparative Study on the Efficacy of MF 59, ISA70 VG, and Nano-Aluminum Hydroxide Adjuvants, Alone and with Nano-Selenium on Humoral Immunity Induced by a Bivalent Newcastle+Avian Influenza Vaccine in Chickens [PDF]

Archives of Razi Institute, 2021
Newcastle disease (ND) and Avian influenza (AI) are the major problems and the most economically important viral diseases in the poultry industry; therefore, vaccination against these diseases is considered one of the most effective ways of prevention ...
M Radmehri, A Talebi, A Ameghi Roudsari, S. M Mousaviyan, M. A. J Gholipour, M Taghizadeh   +5 more
doaj   +1 more source

Vaccine adjuvant MF59 promotes the intranodal differentiation of antigen-loaded and activated monocyte-derived dendritic cells. [PDF]

PLoS ONE, 2017
MF59 is an oil-in-water emulsion adjuvant approved for human influenza vaccination in European Union. The mode of action of MF59 is not fully elucidated yet, but results from several years of investigation indicate that MF59 establishes an ...
Rossella Cioncada, Marcella Maddaluno, Hoa Thi My Vo, Matthew Woodruff, Simona Tavarini, Chiara Sammicheli, Marco Tortoli, Alfredo Pezzicoli, Ennio De Gregorio, Michael C Carroll, Ugo D'Oro, Diego Piccioli   +11 more
doaj   +1 more source