Results 91 to 100 of about 7,531 (200)

Formulation of hepatitis B vaccine in MF59 adjuvant and comparison of its immunization with Iran\'s commercial hepatitis B vaccine

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2018
Introduction: Hepatitis is a systemic diseasethat causes liver inflammation. The prevention of this infection is a vaccination. The commonly used vaccine to fight this disease is to use the vaccine formulated with Alum. This vaccine cannot provide immune
Reyhaneh Mirzaei, Fahimeh Nemati mansour, mehdi mahdavi   +2 more
doaj  

Preventing the Risk of Hospitalization for Respiratory Complications of Influenza among the Elderly: Is There a Better Influenza Vaccination Strategy? A Retrospective Population Study

Vaccines, 2020
Influenza and its complications are an important public health concern, and vaccination remains the most effective prevention measure. However, the efficacy of vaccination depends on several variables, including the type of strategy adopted.
Silvia Cocchio, Tolinda Gallo, Stefania Del Zotto, Elena Clagnan, Andrea Iob, Patrizia Furlan, Marco Fonzo, Chiara Bertoncello, Vincenzo Baldo   +8 more
doaj   +1 more source

Matrix-M™ adjuvation broadens protection induced by seasonal trivalent virosomal influenza vaccine [PDF]

, 2015
Background: Influenza virus infections are responsible for significant morbidity worldwide and therefore it remains a high priority to develop more broadly protective vaccines.
Eirikur Saeland, Freek Cox, Jaap Goudsmit, Jeroen Tolboom, Karin Lövgren Bengtsson, Katarina Radošević, Liesbeth Dekking, Martin Koldijk, Matthijs Baart, Wouter Koudstaal   +9 more
core   +3 more sources

Vaccination in Multiple Myeloma: Challenges and Strategies

European Journal of Haematology, Volume 115, Issue 4, Page 334-343, October 2025.
ABSTRACT Background Multiple myeloma (MM) is a hematological malignancy characterized by profound immunosuppression resulting from both disease‐related mechanisms and treatment‐induced immune dysfunction. This compromised immune status markedly increases susceptibility to infections, a leading cause of morbidity and mortality in MM patients.
Enrica Antonia Martino, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Santino Caserta, Francesco Mendicino, Fortunato Morabito, Massimo Gentile   +10 more
wiley   +1 more source

MF59- and Al(OH)3-adjuvanted Staphylococcus aureus (4C-Staph) vaccines induce sustained protective humoral and cellular immune responses, with a critical role for effector CD4 T cells at low antibody titers.

Frontiers in Immunology, 2015
Staphylococcus aureus (S. aureus) is an important opportunistic pathogen that may cause invasive life-threatening infections like sepsis and pneumonia. Due to increasing antibiotic-resistance, the development of an effective vaccine against S.
Elisabetta eMonaci, Francesca eMancini, Francesca eMancini, Giuseppe eLofano, Giuseppe eLofano, Giuseppe eLofano, Marta eBacconi, Marta eBacconi, Simona eTavarini, Chiara eSammicheli, Letizia eArcidiacono, Monica eGiraldi, Bruno eGaletti, Silvia eRossi Paccani, Antonina eTorre, Maria Rita eFontana, Guido eGrandi, Guido eGrandi, Ennio eDe Gregorio, Giuliano eBensi, Emiliano eChiarot, Sandra eNuti, Fabio eBagnoli, Elisabetta eSoldaini, Sylvie eBertholet   +24 more
doaj   +1 more source

Current Progress in Targeting Human Cytomegalovirus Infection

iLABMED, Volume 3, Issue 3, Page 303-311, September 2025.
This review highlights recent advances in the mechanisms by which human cytomegalovirus (HCMV) maintains its genome in infected cells, as well as the cellular factors and viral antigens that modulate viral reactivation, which reveal potential targets for addressing HCMV infection.
Yonggang Pei, Jun Chen
wiley   +1 more source

Microneedle delivery systems for vaccines and immunotherapy

Smart Molecules, Volume 3, Issue 3, September 2025.
This paper reviews the preparation methods and materials of microneedles for drug delivery, summarizes the structures and types of microneedle systems, analyzes the influence of antigens and adjuvants on the efficacy of microneedle vaccines, and reviews the current application status of microneedles in the fields of vaccines and immunotherapy by ...
Haiyao Jia, Jinyuan Liu, Mengqian Shi, Manzar Abbas, Ruirui Xing, Xuehai Yan   +5 more
wiley   +1 more source

HCV E1E2-MF59 vaccine in chronic hepatitis C patients treated with PEG-IFNα2a and Ribavirin: a randomized controlled trial. [PDF]

, 2013
Hepatitis C virus (HCV) vaccines may be able to increase viral clearance in combination with antiviral therapy. We analysed viral dynamics and HCV-specific immune response during retreatment for experienced patients in a phase Ib study with E1E2MF59 ...
Abrignani, S, Almasio, P, ALMASIO, Pier Luigi, Ascione, A, Bonino, F., Brunetto, MR, Colombatto, P, Houghton, M, Maina, AM, Mondelli, M, Muratori, L, Pinzello, G, Rappuoli, R, Romagnoli, V, Rosa, D, Rumi, MG   +15 more
core   +1 more source

Cladophora wrightiana Var. Minor Extract Acts as an Adjuvant to Promote Natural Killer Cell Activation by Nasal Influenza Vaccine

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
Cladophora wrightiana var. minor (CW) extract, administered as an adjuvant with inactivated influenza virus (iPR8), stimulates both innate and adaptive immune responses. CW enhances NK cell activation, cytotoxic function, and reciprocal crosstalk with dendritic cells, while also promoting CD8+ T cell responses and antigen‐specific IgG production. These
Thi Len Ho, So Yeon Ahn, Eun‐Ju Ko
wiley   +1 more source

Adjuvants : an essential component of neisseria vaccines [PDF]

, 2009
Adjuvants may be classified into delivery systems and immune potentiator or modulator molecules based on their mechanism of action. Neisseria vaccines containing traditional adjuvants such as aluminium salts have existed for long time, but meningitis ...
Acevedo, R., Balbao, J., Cabrera, O., Cuello, M., del Campo, J., Ferro, Valerie A., Gonzales, E., Romeu, B., Zayas, C.   +8 more
core