Results 101 to 110 of about 5,281 (192)

Il vaccino influenzale adiuvato con MF59: immunogenicità nei confronti di ceppi omologhi ed eterovarianti in soggetti anziani

, 2007
INTRODUZIONE: la combinazione dell’adiuvante MF59 agli antigeni influenzali ha potenziato l’immunogenicità del vaccino a subunità, assicurando negli anziani un’efficacia protettiva superiore rispetto ai convenzionali.
TRIVELLO, RENZO, E. MOGLIANI, M. E. SPINELLI, BALDO, VINCENZO, S. MAJORI, BALDOVIN, TATJANA   +5 more
core  

Fast rise of broadly cross-reactive antibodies after boosting long-lived human memory B cells primed by an MF59 adjuvanted prepandemic vaccine

, 2009
Proactive priming before the next pandemic could induce immune memory responses to novel influenza antigens. In an open-label study, we analyzed B cell memory and antibody responses of 54 adults who received 2 7.5-μg doses of MF59-adjuvanted A/Vietnam ...
Carmine Malzone (7588796), Maria C. Zambon (7588802), Joshua DeVos (238785), Grazia Galli (446450), Chiara Gentile (267314), Angelika Banzhoff (267288), Volker Brauer (267317), Karl G. Nicholson (7583588), Iain Stephenson (275990), Katja Hoschler (275985), Flora Castellino (222689), Monia Bardelli (446440), Kathy Hancock (123036), Jacqueline M. Katz (7588805), Teresa McNally (2537689), Michaela Praus (7588793), Guiseppe Del Giudice (7588799), Emanuele Montomoli (234493)   +17 more
core   +2 more sources

Increased immunogenicity of the MF59-adjuvanted influenza vaccine compared to conventional subunit vaccine in elderly subjects.

, 2001
Three-hundred and eight outpatient elderly subjects (> or = 65 years) were randomly assigned to receive the MF59-adjuvanted influenza vaccine (FLU-AD; n = 204) or a conventional subunit influenza vaccine (AGRIPPAL S1; n = 104) in order to compare the ...
GASPARINI, ROBERTO, POZZI T, SENATORE F, MONTOMOLI E, PODDA A., MINUTELLO M, FRAGAPANE E   +6 more
core   +1 more source

Differential Regulation of DC Function, Adaptive Immunity, and MyD88 Dependence by Two Squalene Emulsion-Based Vaccine Adjuvants

Vaccines
MF59 and AS03 are squalene emulsion-based vaccine adjuvants with similar compositions and droplet sizes. Despite their broad use in licensed influenza vaccines, few studies compared their adjuvant effects and action mechanisms side by side.
Jayachandra Reddy Nakkala, Yibo Li, Labone Akter, Xinliang Kang, Xinyuan Chen   +4 more
doaj   +1 more source

Increased immunogenicity of the MF59-adjuvanted influenza vaccine compared to a conventional subunit vaccine in elderly subjects

, 2001
Three-hundred and eight outpatient elderly subjects (> or = 65 years) were randomly assigned to receive the MF59-adjuvanted influenza vaccine (FLU-AD; n = 204) or a conventional subunit influenza vaccine (AGRIPPAL S1; n = 104) in order to compare the ...
Pozzi, T., Montomoli, E., Minutello, M., Senatore, F., Podda, A., Gasparini, R., Fragapane, E.   +6 more
core   +1 more source

Safety and immunogenicity of a monovalent MF59®-adjuvanted A/H1N1 vaccine in HIV-infected children and young adults

, 2012
This Phase IV study evaluated the safety and immunogenicity of a two-dose, MF59®-adjuvanted (Novartis Vaccines, Marburg, Germany), monovalent, A/H1N1 pandemic influenza vaccination schedule in Human Immunodeficiency Virus (HIV) positive children and ...
Douagi, I., ROSSI, PAOLO, Tchidjou, H, Pontrelli, G, Rossi, P, Alghisi, F, Bernardi, S, Santilli, V, Lucidi, V, ROMITI, MARIA LUISA, Mora, N, Cotugno, N, Douagi, I, Aquilani, A, Romiti, M, Palma, P, Romiti, ML, Tchidjou, HK   +17 more
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Construction and Immune Strategy Optimization of a Vaccine Strain for Influenza A (H5N8) Subtype

Viruses
Multiple subtypes of avian influenza virus (AIV), including H5N1, H5N6, and H5N8 viruses, are currently co-circulating in wild birds and poultry and causing sporadic human infections. Vaccine development is essential for pandemic preparedness.
Shuxia Zhang, Jing Tang, Liqi Liu, Hejiang Wei, Li Xin, Kang Xiao, Jinbo Xiao, Jie Dong, Zi Li, Hongyan Bai, Shuaixing Wang, Wenfei Zhu, Lei Yang, Shumei Zou, Dayan Wang   +14 more
doaj   +1 more source

MF59 adjuvanted seasonal and pandemic influenza vaccines.

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2012
MF59-adjuvanted seasonal trivalent inactivated (ATIV) vaccine licensed since 1997 and MF59-adjuvanted pandemic H1N1 vaccines have been distributed to approximately 80M persons. Addition of the emulsion adjuvant to inactivated vaccine formulations provides for higher levels of antibody to the viral hemagglutinin (HA) in less responsive older adults ...
openaire   +1 more source

The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination [PDF]

, 2014
Vaccines are the most effective agents to control infections [1]. In addition to the pathogen antigens, vaccines contain adjuvants that are used to enhance the specific immune responses.
Vono, Maria
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Serum IgG subclass responses in goats subcutaneously vaccinated with inactivated CpHV-1 plus MF59™.

, 2013
Vaccines were given on day 0 and day 10. Sera were collected on day 20 to determine CpHV-1-specific IgG1 titers (white histograms) and CpHV-1-specific IgG2 titers (black histograms) by ELISA. Data are expressed as arithmetic mean ± SD.
Giovanni Rezza (272639), Mariarosaria Marinaro (290802), Valeriana Colao (326867), Elvira Tarsitano (85488), Michele Camero (85487), Maria Tempesta (85486), Michele Losurdo (290798), Canio Buonavoglia (85490), Giuseppe Del Giudice (222696)   +8 more
core   +1 more source