Results 101 to 110 of about 5,863 (219)
Chemistry – A European Journal, Volume 31, Issue 28, May 19, 2025.The synthesis of betulinic acid and echinocystic acid saponins featuring QS‐21 minimal immunogenic motif is reported. These chimeric saponins, together with previously synthesized Lewis‐X‐containing triterpenoid saponins and a rhamnose‐modified saponin, were assessed for their toxicological and immunological profiles in wild‐type and/or hDC‐SIGN ...
Oscar Javier Gamboa Marin +9 more
wiley +1 more source
Current prospects and future challenges for nasal vaccine delivery [PDF]
, 2016 Nasal delivery offers many benefits over traditional approaches to vaccine administration. These include ease of administration without needles that reduces issues associated with needlestick injuries and disposal.
Kett, Vicky, Yusuf, Helmy
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Вопросы вирусологии, 2019 The review article presents the characteristics of the main adjuvant groups (mineral salts of aluminum, synthetic squalene-based adjuvants - MF59 and AS03, CpG-oligodeoxynucleotides, virosomes, polyoxidonium, sovidone) included in the licensed influenza ...
T. A. Kuznetsova +3 more
doaj +1 more source
Influenza Virus Vaccine Efficacy Based On Conserved Sequence Alignment
, 2012 The rapid outbreak of bird flu challenges the outcome of effective vaccine for the upcoming years. The recent research established different norms to eliminate flu pandemics.
Jerald, Baby, Nair, T. R. Gopalakrishnan
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Down selecting adjuvanted vaccine formulations: a comparative method for harmonized evaluation. [PDF]
, 2018 The need for rapid and accurate comparison of panels of adjuvanted vaccine formulations and subsequent rational down selection, presents several challenges for modern vaccine development.
A Tanghe +39 more
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Poly(Anhydride) Nanoparticles Act as Active Th1 Adjuvants through Toll-Like Receptor Exploitation [PDF]
, 2010 The mechanisms that underlie the potent Th1-adjuvant capacity of poly(methyl vinyl ether-co-maleic anhydride) nanoparticles (NPs) were investigated.
Gamazo, C. (Carlos) +5 more
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Matrix-M™ adjuvant enhances immunogenicity of both protein- and modified vaccinia virus Ankara-based influenza vaccines in mice [PDF]
, 2018 Influenza viruses continuously circulate in the human population and escape recognition by virus neutralizing antibodies induced by prior infection or vaccination through accumulation of mutations in the surface proteins hemagglutinin (HA) and ...
Altenburg, A.F. (Arwen) +6 more
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, 2009 Summary Background: When H1N1v vaccines become widely available, most elderly subjects will have already received their seasonal influenza vaccination. Adults seeking H1N1v vaccination may be offered seasonal vaccine as well. We investigated prior seasonal vaccination in adult and elderly subjects, and concomitant vaccination with seasonal vaccine in ...
M. Barone +7 more
openaire +1 more source
PLoS ONE, 2016 BackgroundThe safety and immunogenicity of SAAVI DNA-C2 (4 mg IM), SAAVI MVA-C (2.9 x 109 pfu IM) and Novartis V2-deleted subtype C gp140 (100 mcg) with MF59 adjuvant in various vaccination regimens was evaluated in HIV-uninfected adults in South Africa ...
Gavin Churchyard +20 more
doaj +1 more source
Aqueous extract of Calamus rotang as a novel immunoadjuvant enhances both humoral and cell mediated immune response [PDF]
, 2017 Introduction: Search for new adjuvants for human vaccines has become an expanding field of research in the last thirty years for generating stronger vaccines, capable of inducing protective and long lasting immunity in humans. The objective of this study
Chaphalkar, S.R. +2 more
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