Mff functions with Pex11pβ and DLP1 in peroxisomal fission [PDF]
Biology Open, 2013 Summary Peroxisomal division comprises three steps: elongation, constriction, and fission. Translocation of dynamin-like protein 1 (DLP1), a member of the large GTPase family, from the cytosol to peroxisomes is a prerequisite for membrane fission ...
Yukio Fujiki +2 more
exaly +5 more sources
MFF budding from mitochondria regulates melanosome size and maturation [PDF]
Nature CommunicationsMelanosomes are lysosome-related organelles that produce and accumulate melanin. Their maturation is regulated through interactions with mitochondria and involves the export and recycling of proteins via tubular transport and fission events whose ...
Ana Paula Magalhães Rebelo +14 more
doaj +6 more sources
Frontiers in Cell and Developmental Biology, 2021 Drp1 is a central player in mitochondrial fission and is recruited to mitochondria by Mff and MIEFs (MIEF1 and MIEF2), but little is known about how its assembly state affects Drp1 mitochondrial recruitment and fission.
Jian Zhao +2 more
exaly +3 more sources
Association between TMG-derived contractile muscle parameters and MRI-based muscle structure in sarcopenia [PDF]
BMC Musculoskeletal DisordersBackground Muscle fat fraction (MFF) obtained through magnetic resonance imaging (MRI) is the gold standard for assessing muscle quality, but it is expensive and time consuming.
Katarina Pus +5 more
doaj +2 more sources
A PKD-MFF signaling axis couples mitochondrial fission to mitotic progression
Cell Reports, 2021 Summary: Mitochondria are highly dynamic organelles subjected to fission and fusion events. During mitosis, mitochondrial fission ensures equal distribution of mitochondria to daughter cells. If and how this process can actively drive mitotic progression
Eva Pangou +2 more
exaly +3 more sources
FEBS Open Bio, 2019 Mitochondrial fission regulates mitochondrial function and morphology, and has been linked to apoptosis. The mitochondrial fission factor (Mff), a tail‐anchored membrane protein, induces excessive mitochondrial fission, contributing to mitochondrial ...
Tongsheng Chen
exaly +2 more sources
CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity [PDF]
Cell, 2019 Ectopic lipid deposition and altered mitochondrial dynamics contribute to the development of obesity and insulin resistance. However, the mechanistic link between these processes remained unclear. Here we demonstrate that the C16:0 sphingolipid synthesizing ceramide synthases, CerS5 and CerS6, affect distinct sphingolipid pools and that abrogation of ...
Marcus Kruger +2 more
exaly +5 more sources
Predicting the Nonunion of the Acute Osteoporotic Vertebral Compression Fracture Following Low‐Energy Injuries by Quantifying Vertebral Marrow Fat Fraction on T2‐Weighted Dixon Sequences [PDF]
Orthopaedic SurgeryObjective Increased marrow fat fraction (MFF) of vertebrae was detected in patients with osteoporosis. However, MFF of the fractured vertebrae decreased significantly following the fracture.
Pengguo Gou +4 more
doaj +2 more sources
MLP-MFF: Lightweight Pyramid Fusion MLP for Ultra-Efficient End-to-End Multi-Focus Image Fusion [PDF]
SensorsLimited depth of field in modern optical imaging systems often results in partially focused images. Multi-focus image fusion (MFF) addresses this by synthesizing an all-in-focus image from multiple source images captured at different focal planes.
Yuze Song +4 more
doaj +2 more sources
MicroRNA-27b alleviates septic cardiomyopathy by targeting the Mff/MAVS axis [PDF]
Frontiers in Cellular and Infection MicrobiologyObjectiveTo investigate the protective role of microRNA-27b (miR-27b) in septic cardiomyopathy (SCM) and its regulatory mechanism on the mitochondrial fission factor (Mff)/mitochondrial antiviral signaling protein (MAVS) axis.MethodsTranscriptome data ...
Xincai Wang +8 more
doaj +2 more sources