Results 11 to 20 of about 39,147 (253)

Quantifying the inhibitory effect of Bcl‐xl on the action of Mff using live‐cell fluorescence imaging

open access: yesFEBS Open Bio, 2019
Mitochondrial fission regulates mitochondrial function and morphology, and has been linked to apoptosis. The mitochondrial fission factor (Mff), a tail‐anchored membrane protein, induces excessive mitochondrial fission, contributing to mitochondrial ...
Tongsheng Chen
exaly   +2 more sources

MLP-MFF: Lightweight Pyramid Fusion MLP for Ultra-Efficient End-to-End Multi-Focus Image Fusion [PDF]

open access: yesSensors
Limited depth of field in modern optical imaging systems often results in partially focused images. Multi-focus image fusion (MFF) addresses this by synthesizing an all-in-focus image from multiple source images captured at different focal planes.
Yuze Song   +4 more
doaj   +2 more sources

CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity [PDF]

open access: yesCell, 2019
Ectopic lipid deposition and altered mitochondrial dynamics contribute to the development of obesity and insulin resistance. However, the mechanistic link between these processes remained unclear. Here we demonstrate that the C16:0 sphingolipid synthesizing ceramide synthases, CerS5 and CerS6, affect distinct sphingolipid pools and that abrogation of ...
Hendrik Nolte   +2 more
exaly   +5 more sources

MIEF1/2 function as adaptors to recruit Drp1 to mitochondria and regulate the association of Drp1 with Mff

open access: yesScientific Reports, 2017
Mitochondrial dynamics is a fundamental cellular process and recruitment of Drp1 to mitochondria is an essential step in mitochondrial fission. Mff and MIEF1/2 (MiD51/49) serve as key receptors for recruitment of Drp1 to mitochondria in mammals. However,
Rong Yu, Tong Liu, Urban Lendahl
exaly   +2 more sources

Mitochondrial fission factor drives an actionable metabolic vulnerability in multiple myeloma [PDF]

open access: yesHaematologica
Proliferating multiple myeloma (MM) cells in the bone marrow fluctuate across various metabolic states to resist cancer treatments. Herein, we investigate how mitochondrial dynamics, which controls mitochondrial fitness via coordinated fission and ...
Maria Eugenia Gallo Cantafio   +19 more
doaj   +2 more sources

The mitochondrial fission receptor Mff selectively recruits oligomerized Drp1

open access: greenMolecular Biology of the Cell, 2015
Dynamin-related protein 1 (Drp1) is the GTP-hydrolyzing mechanoenzyme that catalyzes mitochondrial fission in the cell. Residing in the cytosol as dimers and tetramers, Drp1 is recruited by receptors on the mitochondrial outer membrane, where it further assembles into a helical ring that drives division via GTP-dependent constriction.
Raymond Liu, David C. Chan
openalex   +5 more sources

MFF: A Deep Learning Model for Multi-Modal Image Fusion Based on Multiple Filters

open access: goldIEEE Access
Multi-modal image fusion mainly refers to the feature fusion of two or more different images taken from the same perspective range to increase the amount of information contained in an image.
Yuequn Wang   +6 more
doaj   +2 more sources

Environmental ciprofloxacin triggers pregnancy loss: senescence-driven miscarriage via TRIM21-mediated MFF degradation. [PDF]

open access: goldEBioMedicine
Sun 孙义 Y   +14 more
europepmc   +2 more sources

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