Results 61 to 70 of about 11,596 (171)
The Journal of Physiology, EarlyView.Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source
PLoS ONE, 2019 The mitochondrial outer membrane protein Mitochondrial Fission Factor (Mff) plays a key role in both physiological and pathological fission. It is well established that at stressed or functionally impaired mitochondria, PINK1 recruits the ubiquitin ...
Laura Lee +4 more
doaj +1 more source
SARS‐CoV‐2 targets mitochondria, exacerbating COVID‐19 pneumonia
The Journal of Physiology, EarlyView.Abstract figure legend Following entry into airway epithelial cells (AECs), SARS‐CoV‐2 releases its single‐stranded RNA into the cytoplasm, where it is translated into viral proteins. Several of these viral proteins localize to mitochondria and interact with key mitochondrial components.
Danchen Wu +5 more
wiley +1 more source
Hypoxia‐induced vulnerability of the somatosensory nervous system
The Journal of Physiology, EarlyView.Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
wiley +1 more source
Computational and Systems Oncology, Volume 6, Issue 1, December 2026.ABSTRACT Breast cancer is still a serious problem in the world arena, where its early and prompt detection is the most important factor in improving patient prognosis and survival. The use of traditional diagnostic techniques, such as imaging (e.g., mammography and ultrasound) and subsequent histopathological examination, is the mainstay, which ...
Likhon Chandra Sarkar +6 more
wiley +1 more source
SUMOylation of MFF is required for stress-induced mitochondrial fission
, 2023 Abstract Mitochondrial fission regulates mitochondrial morphology, function, mitophagy and apoptosis. Fission is mediated by the GTPase dynamin related protein-1 (DRP1) and its recruitment to the outer mitochondrial membrane by DRP1 receptors.
Seager, R. +5 more
openaire +2 more sources
Metal Fume Fever among Galvanized Welders
Acta Medica Indonesiana, 2016 The metal fume fever (MFF) is an inhalation fever syndrome in welders of galvanized steel, who join and cut metal parts using flame or electric arc and other sources of heat.
Wardhana Wardhana, E.A. Datau
doaj +2 more sources
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017 Background The cardiac microvascular system ischemia/reperfusion injury following percutaneous coronary intervention is a clinical thorny problem. This study explores the mechanisms by which ischemia/reperfusion injury induces cardiac microcirculation ...
Hao Zhou +8 more
doaj +1 more source
Through the Looking Glass: Uncovering the EU's Gendered Foreign Policy to Afghanistan
Contemporary European Politics, Volume 4, Issue 3, September 2026.ABSTRACT Afghanistan has consistently ranked among the most challenging contexts for the promotion of women's rights. This situation has intensified with the Taliban's return to power in August 2021 and the subsequent consolidation of what has been termed a system of gender apartheid.
Luís Matos
wiley +1 more source
Clinical Genetics, Volume 110, Issue 3, Page 336-346, September 2026.Opticus atrophy—Genetic testing with WES/WGS in 62 patients with optic atrophy provided a genetic diagnosis in 21 patients (33.9%). 42.9% of these involved non‐OPA1 genes, including WFS1, ACO2, NR2F1, UCHL1, CACNA1F, and COQ2, where the genetic diagnosis prompted additional clinical evaluation, surveillance, or therapeutic intervention.
Katrine M. Johannesen +9 more
wiley +1 more source