Results 61 to 70 of about 57,247 (319)

MgAlSi Üçlü Alaşımının Üretimi ve in-vitro biyo Uyumluluk İncelemesi

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2023
Bu çalışmada biyo uyumlu Mg metali ile birlikte Al ve Si elementlerini içeren bir alaşım üretilmiştir. Üretim işlemi indüksiyon ocağında ergiterek yapılmıştır.
Bünyamin Çiçek, Hanife Çakal, Esma Elmacı, Yusuf Sağır   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Texture Evolution of AZ31 Magnesium Alloy Sheet at High Strain Rates

, 2010
In the current contribution the mechanical behaviour at high strain rates of AZ31 magnesium alloy sheet is studied. Uniaxial deformation properties were studied by means of tensile split Hopkinson pressure bar (SHPB) at different temperatures.
Hurtado, I., Letzig, D., Gálvez, F., Yi, S., Pérez-Prado, M. T., Dudamell, N. V., Pérez Prado, María Teresa, Dudamell, N.V., Ulacia, I., Gálvez Díaz-Rubio, Francisco   +9 more
core   +1 more source

Phase-field modeling and Experimental investigation for rapid solidification in wire and arc additive manufacturing

Journal of Materials Research and Technology
The rapid solidification speed and significant temperature gradient observed in the wire and arc additive manufacturing (WAAM) process result in a deviation of the solid-liquid interface from the equilibrium state assumed by the conventional directional ...
Fuchen Wang, Weipeng Chen, Dong Wang, Hua Hou, Yuhong Zhao   +4 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Antibacterial biodegradable Mg-Ag alloys

European Cells and Materials, 2013
The use of magnesium alloys as degradable metals for biomedical applications is a topic of ongoing research and the demand for multifunctional materials is increasing. Hence, binary Mg-Ag alloys were designed as implant materials to combine the favourable properties of magnesium with the well-known antibacterial property of silver. In this study, three
Tie, D., Feyerabend, F., Mueller, W.-D., Schade, R., Liefeith, K., Kainer, K.U., Willumeit, R.   +6 more
openaire   +4 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Control of Magnesium Alloy Corrosion through the Use of Engineered Intermetallics [PDF]

, 2014
The low density and high relative strength of Mg alloys means they can offer engineering benefits over steels or Al alloys. However, the susceptibility of Mg alloys to corrosion has limited their exploitation and restricted their use to more benign ...
Pidcock, Andrew
core  

Environment-COnscious magnesium (ECO-Mg): A review

Cleaner Materials
The significance of Mg (alloy) extends to both the mechanical engineering and medical sectors. However, Mg is known for its high reactivity, posing significant challenges to its widespread utilization in large-scale lightweight applications. Research has
Shahabodin Rafiei, Ali Habibolahzadeh, Björn Wiese   +2 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source