Results 71 to 80 of about 220,287 (359)

Development of a super ductile diecast Al-Mg-Si alloy [PDF]

, 2012
This is the post-print version of the final paper published in Materials Science and Engineering A. The published article is available from the link below.
Fan, Z, Watson, D, White, M
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Environment-COnscious magnesium (ECO-Mg): A review

Cleaner Materials
The significance of Mg (alloy) extends to both the mechanical engineering and medical sectors. However, Mg is known for its high reactivity, posing significant challenges to its widespread utilization in large-scale lightweight applications. Research has
Shahabodin Rafiei, Ali Habibolahzadeh, Björn Wiese   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Development Of Al-B-C Master Alloy Under External Fields [PDF]

, 2015
This study investigates the application of external fields in the development of an Al-B-C alloy, with the aim of synthesizing in situ Al3BC particles. A combination of ultrasonic cavitation and distributive mixing was applied for uniform dispersion of ...
A. Rogers, B. Bramfitt, B. Lee, Dmitry G. Eskin, G. Arslan, G. Eskin, G. Ma, Hari Babu Nadendla, I. Ibrahim, I. Stone, J. Curtis, J. Lewandowski, J. Wang, K. Lee, M. Zhang, N. Aniban, N. Barekar, N. Harnby, P. Karnezis, R. Riedel, S. Liu, S. Madam, S. Ray, Sreekumar VadakkeMadam, T. Clyne, Utsavi Joshi, W. Spitzig, W. Tian, Z. Luo   +28 more
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Simultaneously improving thermal conductivity, mechanical properties and metal fluidity through Cu alloying in Mg-Zn-based alloys

Journal of Magnesium and Alloys
Mg-Zn-based alloys have been widely used in computer, communication, and consumer (3C) products due to excellent thermal conductivity. However, it is still a challenge to balance their mechanical performance and thermal conductivity. Here, we investigate
Yuntao Zhang, Wei Liu, Weipeng Chen, Zhiqiang Li, Hua Hou, Yuhong Zhao   +5 more
doaj   +1 more source

Breast tumor diagnosis in digital mammograms [PDF]

, 2019
Breast cancer has been classified as the most common cancer in most part of the world [1]. Breast cancer is caused by the growth of the abnormal cells in the breast. Breast cancer not only develops in women but also on men.
Gaik Tay, Kim, Huong, Audrey, Yang Lim, Xiang   +2 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Zjemňování zrna protlačované hořčíkové slitiny AZ31 procesem Ecap [PDF]

, 2017
Extruded Mg – 3%Al – 1% Zn (AZ31) magnesium alloy was subjected to ECAP (Equal Channel Angular Pressing) processing at 523 K (250 °C). At the processing temperature of 523 K, fine grains with the average grain size of 2 – 3 μm are formed as a result of ...
Hilšer, Ondřej, Krejčí, Lucie, Rusz, Stanislav, Špalek, František   +3 more
core   +1 more source