Results 41 to 50 of about 505,271 (361)

Major Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation

Frontiers in Immunology, 2017
Antigen presentation by major histocompatibility complex (MHC) proteins is essential for adaptive immunity. Prior to presentation, peptides need to be generated from proteins that are either produced by the cell’s own translational machinery or that are ...
M. Wieczorek, Esam T. Abualrous, J. Sticht, Miguel Álvaro-Benito, Sebastian Stolzenberg, F. Noé, C. Freund   +6 more
semanticscholar   +1 more source

The Major Histocompatibility Complex of Old World Camels—A Synopsis

Cells, 2019
This study brings new information on major histocompatibility complex (MHC) class III sub-region genes in Old World camels and integrates current knowledge of the MHC region into a comprehensive overview for Old World camels.
Martin Plasil, Sofia Wijkmark, Jean Pierre Elbers, Jan Oppelt, Pamela Anna Burger, Petr Horin   +5 more
doaj   +1 more source

Statistical deconvolution of enthalpic energetic contributions to MHC-peptide binding affinity [PDF]

, 2006
Background: MHC Class I molecules present antigenic peptides to cytotoxic T cells, which forms an integral part of the adaptive immune response. Peptides are bound within a groove formed by the MHC heavy chain. Previous approaches to MHC Class I-peptide
Davies, M.N., Drew, M.G.B., Flower, D.R., Hattotuwagama, C.K., Moss, David S.   +4 more
core   +3 more sources

Improved prediction of MHC II antigen presentation through integration and motif deconvolution of mass spectrometry MHC eluted ligand data

bioRxiv, 2019
Major Histocompatibility Complex II (MHC II) molecules play a key role in the onset and control of cellular immunity. In a highly selective process, MHC II presents peptides derived from exogenous antigens on the surface of antigen presenting cells for T
Birkir Reynisson, C. Barra, S. Kaabinejadian, W. Hildebrand, Bjoern Peters, M. Nielsen   +5 more
semanticscholar   +1 more source

Expression of MHC Class I and II in Growing Ovarian Follicles of Young and Old Laying Hens, Gallus domesticus

The Journal of Poultry Science, 2005
The aim of this study was to determine whether the expressions of MHC class I and II in the ovarian follicles change with follicular growth and aging of birds. Theca layer of white follicles (WF), the largest and the third largest preovulatory follicles
Kalpana Subedi, Yukinori Yoshimura
doaj   +1 more source

Class I major histocompatibility complexes loaded by a periodate trigger [PDF]

, 2009
Class I major histocompatibility complexes (MHCs) present peptide ligands on the cell surface for recognition by appropriate cytotoxic T cells. The unstable nature of unliganded MHC necessitates the production of recombinant class I complexes through in ...
Adams P. D., Back J. W., Bakker A. H., Bosques C. J., Bouvier M., Buist G. J., CCP4 (Collaborative Computational Project, No. 4), Chen D., Cobbold M., Emsley P., Evans P. R., Falkenburg J. H., Fremont D. H., Frickel E. M., Garboczi D. N., Gredmark-Russ S., Grotenbreg G. M., Grotenbreg G. M., Kamiya T., Leslie A. G. W., Ljunggren H. G., Madden D. R., Moroder L., Moss P., Murshudov G. N., Peggs K. S., Rammensee H., Rodenko B., Rooney C. M., Rosenberg S. A., Schumacher T. N., Schumacher T. N., Silver M. L., Soen Y., Stone J., Toebes M., Vriend G., Walter E. A., Yee C.   +38 more
core   +1 more source

Two polymorphisms facilitate differences in plasticity between two chicken major histocompatibility complex class I proteins [PDF]

, 2014
Major histocompatibility complex class I molecules (MHC I) present peptides to cytotoxic T-cells at the surface of almost all nucleated cells. The function of MHC I molecules is to select high affinity peptides from a large intracellular pool and they ...
Bailey, Alistair, Elliott, Tim, van Hateren, Andy, Werner, Jörn M.   +3 more
core   +9 more sources

Fine Mapping of the MHC Region Identifies Novel Variants Associated with HBV-Related Hepatocellular Carcinoma in Han Chinese

Journal of Hepatocellular Carcinoma, 2021
Haoming Mai,1,* Jiaxuan Chen,1,* Haitao Chen,1,2,* Zhiwei Liu,3,* Guanlin Huang,1 Jialin Wang,1 Qianyi Xiao,4 Weihua Ren,5 Bin Zhou,1 Jinlin Hou,1 Deke Jiang1 1State Key Laboratory of Organ Failure Research, Guangdong Key Laboratory of ...
Mai H, Chen J, Chen H, Liu Z, Huang G, Wang J, Xiao Q, Ren W, Zhou B, Hou J, Jiang D   +10 more
doaj  

Designing for Meaningful Human Control in Military Human-Machine Teams [PDF]

arXiv, 2023
We propose methods for analysis, design, and evaluation of Meaningful Human Control (MHC) for defense technologies from the perspective of military human-machine teaming (HMT). Our approach is based on three principles. Firstly, MHC should be regarded as a core objective that guides all phases of analysis, design and evaluation.
arxiv  

Diversity of MHC IIB genes and parasitism in hybrids of evolutionarily divergent cyprinoid species indicate heterosis advantage

Scientific Reports, 2021
The genes of the major histocompatibility complex (MHC) are an essential component of the vertebrate immune system and MHC genotypes may determine individual susceptibility to parasite infection.
Andrea Šimková, Lenka Gettová, Kristína Civáňová, Mária Seifertová, Michal Janáč, Lukáš Vetešník   +5 more
doaj   +1 more source