Results 171 to 180 of about 534,915 (376)
Advanced Science, EarlyView.Tumor‐informed circulating tumor DNA (ctDNA) analysis identifies patients with advanced non‐small cell lung cancer (NSCLC) who benefit from first‐line immunotherapy plus chemotherapy. Longitudinal ctDNA monitoring further reflects therapeutic response and predicts prognosis beyond imaging.
Kailun Fei +16 more
wiley +1 more source
T cell recognition of nonpolymorphic determinants on H-2 class I molecules. [PDF]
, 1988 Recognition of polymorphic determinants on class I or class II MHC Ag is required for T lymphocyte responses. Using cell-size artificial membranes (pseudocytes) bearing H-2 class I Ag it is demonstrated that T cells can, in addition, recognize ...
Goldstein, SA, Mescher, MF
core
The ins and outs of MHC class II-mediated antigen processing and presentation
Nature reviews. Immunology, 2015 P. Roche, K. Furuta
semanticscholar +1 more source
Advanced Science, EarlyView.This study presents an engineered human interferon‐lambda (hIFN‐λ) as an intranasal prophylactic against respiratory viruses. By combining AI‐guided backbone redesign and glycoengineering, the authors developed a thermostable, protease‐resistant, and scalable variant with improved mucosal penetration.
Jeongwon Yun +12 more
wiley +1 more source
Differential expression of MHC class II antigens in myelomonocytic leukemia cell lines [PDF]
, 1989 Juan J. Yunis +3 more
openalex +1 more source
Advanced Science, EarlyView.Impaired anti‐tumor immunity is mediated by TREM2 + macrophages in non‐small cell lung cancer. TREM2 + macrophages prevent anti‐tumor immunity depending on the limitation of CD4 + T and NK cells. TREM2 promotes cholesterol efflux via ABCA1 to limit the production of CX3CL1 in macrophages.
Yunhan Wang +9 more
wiley +1 more source
Antigen-specific stimulation of T cell extracellular acidification by MHC class II-peptide complexes [PDF]
, 1992 Bishwajit Nag +7 more
openalex +1 more source
Mutant MHC class II epitopes drive therapeutic immune responses to cancer
Nature, 2015 S. Kreiter +14 more
semanticscholar +1 more source
METTL10‐Mediated PIAS3 Methylation Links Purine Metabolism to Gastric Cancer Progression
Advanced Science, EarlyView.METTL10‐mediated methylation of PIAS3 at K442 inhibits its SUMO E3 ligase activity toward MITF. This reduces MITF SUMOylation and subsequent RNF4‐mediated ubiquitination, leading to MITF protein accumulation and gastric cancer progression. Abstract Metabolic dysregulation plays a significant role in the development of gastric cancer (GC).
Jinshui Tan +20 more
wiley +1 more source