Lack of association between alopecia areata and HLA class I and II in a southeastern Brazilian population [PDF]
Anais Brasileiros de Dermatologia, 2016 : Background: Alopecia areata (AA) is a common disorder of unknown etiology that affects approximately 0.7% to 3.8% of patients among the general population. Currently, genetic and autoimmune factors are emphasized as etiopathogenic.
Ângela Marques Barbosa +7 more
doaj +1 more source
Computational and Structural Biotechnology Journal, 2023 The aggregation of epitopes that are also able to bind major histocompatibility complex (MHC) alleles raises questions around the potential connection between the formation of epitope aggregates and their affinities to MHC receptors. We first performed a
Rodrigo Ochoa +4 more
doaj +1 more source
Superantigen and class II MHC molecules [PDF]
Journal of Korean Medical Science, 1995 open
openaire +3 more sources
Schistosoma japonicum soluble egg antigens attenuate IFN-γ-induced MHC class II expression in RAW 264.7 macrophages. [PDF]
PLoS ONE, 2012 Innate immune response plays the key role in initiating and guiding the immune response. Elucidating the innate immune related molecular events involved in the interaction between the parasite and the host will aid in the development of an effective ...
Gui-Xia Tang +6 more
doaj +1 more source
Antigen processing for MHC class II presentation via autophagy
Frontiers in Immunology, 2012 T cells recognize proteolytic fragments of antigens that are presented to them on major histocompatibility complex (MHC) molecules. MHC class I molecules present primarily products of proteasomal proteolysis to CD8+ T cells, while MHC class II molecules ...
Christian eMunz
doaj +1 more source
Biology, 2022 As an important part of immune surveillance, major histocompatibility complex (MHC) is a set of proteins that recognize foreign molecules. Computational prediction methods for MHC binding peptides have been developed.
Limin Jiang +3 more
doaj +1 more source
Immunohistochemical, morphological and ultrastructural resemblance between dendritic cells and folliculo-stellate cells in normal human and rat anterior pituitaries [PDF]
, 1996 Immunolabeling of cryo-sections of human anterior pituitaries obtained at autopsy, and of cryo-sections of freshly prepared rat anterior pituitaries, with a panel of monoclonal antibodies against markers of the monocyte/dendritic cell/macrophage lineage,
Alberts W +37 more
core +1 more source
Functional Characterization of a Chicken Major Histocompatibility Complex Class II B Gene Promoter [PDF]
, 1997 A 0.7 kilobase (kb) DNA fragment from the 5\u27 flanking region of a chicken major histocompatibility complex (MHC) class II B gene was cloned into chloramphenicol acetyltransferase (CAT) reporter vectors and was transfected into a chicken macrophage ...
Carpenter, Susan +5 more
core +3 more sources
Selection and trans-species polymorphism of major histocompatibility complex class II genes in the order Crocodylia. [PDF]
PLoS ONE, 2014 Major Histocompatibility Complex (MHC) class II genes encode for molecules that aid in the presentation of antigens to helper T cells. MHC characterisation within and between major vertebrate taxa has shed light on the evolutionary mechanisms shaping the
Weerachai Jaratlerdsiri +4 more
doaj +1 more source
Absence of MHC class II on cDCs results in microbial-dependent intestinal inflammation
Journal of Experimental Medicine, 2016 Nussenzweig et al. use a novel mutant mouse lacking MHC class II expression on conventional dendritic cells (cDCs) to demonstrate the importance of cDCs in the maintenance of intestinal homeostasis.
Jakob Loschko +10 more
semanticscholar +1 more source