Results 111 to 120 of about 1,517 (162)

Distribution of M2 null virus in newly formed, marginal zone and follicular B cells in the spleen at the peak of latency is similar to wild type MHV68.

, 2013
(A and B) Insertion of a YFP expression cassette into the viral genome, or addition of an AU1 epitope tag on the C-terminus of M2, did not alter the phenotype of the M2 null virus.
Neal N. Iwakoshi (369025), Justin B. Mendel (369024), Samuel H. Speck (70359), Christopher M. Collins (309503), Xiaozhen Liang (206573)   +4 more
core   +1 more source

MHV68 suppresses splenic B cell responses during co-infection with Plasmodium.

, 2015
The timeline and experimental set up was identical to that shown in Fig 1A. (A) Absolute numbers of splenic GC B cell populations (B220+ GL7+ CD95+) during P. yoelii XNL and P.
Caline G. Matar (742589), Neil R. Anthony (528857), Samuel H. Speck (70359), Tracey J. Lamb (659393), Lalita Priyamvada (421536), Brigid M. O’Flaherty (615607), Christian R. Engwerda (42442), Nathan T. Jacobs (742590)   +7 more
core   +1 more source

Label-free, quantitative phosphoproteomic analyses identify phosphoproteins induced and repressed in MHV68 infection.

, 2013
(A) Serum-starved 3T3 fibroblasts were mock-infected or infected at MOI = 5 PFU/cell, and cells were harvested 18 h post-infection, the timepoint for which tryptic peptides were enriched by TiO2 IMAC and identified by high resolution mass spectrometry ...
Daniel E. Voth (196250), J. Craig Forrest (308744), James A. Stahl (460566), Shweta S. Chavan (460567), Jeffrey M. Sifford (460568), Veronica MacLeod (460569), Ricky D. Edmondson (460570)   +6 more
core   +1 more source

mLANA represses a promoter that initiates transcription within the MHV68 terminal repeat (TR).

, 2013
(A) Schematic illustration of mLANA gene transcription arising from 2 distinct promoters, one in the unique region adjacent the MHV68 TR, and the other within the TR.
Samuel H. Speck (70359), Clinton R. Paden (206576), Scott A. Tibbetts (244898), J. Craig Forrest (308744)   +3 more
core   +1 more source

A combination of proviral and antiviral roles of CD11c- and T-bet-expressing B cells defines parameters of chronic murine gammaherpesvirus infection. [PDF]

mBio
Johansen ER, Bradeen XG, Xie EV, Dittel BN, Leadbetter EA, Tarakanova VL.   +5 more
europepmc   +1 more source

B cell-intrinsic interleukin 17 receptor A signaling supports the establishment of chronic murine gammaherpesvirus 68 infection. [PDF]

J Virol
Majeed ST, Huss NP, Bradford SM, Jondle CN.   +3 more
europepmc   +1 more source

B cell-intrinsic IRF-1 and conserved gammaherpesvirus protein kinase cooperate to promote murine gammaherpesvirus-driven germinal center response and splenic latent reservoir. [PDF]

J Virol
Rahlf CR, Jondle CN, Johansen ER, Tarakanova VL.   +3 more
europepmc   +1 more source

A Role for the Hypoxia-Inducible Factor 1 Alpha in Murine Gammaherpesvirus 68 (MHV68) Lytic Replication and Reactivation from Latency

, 2019
The hypoxia inducible factor 1 alpha (HIF1α) protein and the hypoxic microenvironment are critical for infection and pathogenesis by the oncogenic gammaherpesviruses (γHV) such as Kaposi' Sarcoma-associated Herpes Virus (KSHV) and Epstein-Barr virus (EBV)
López-Rodríguez, Darlah
core  

RNA polymerase III transcription-associated polyadenylation promotes the accumulation of noncoding retrotransposons during infection. [PDF]

Proc Natl Acad Sci U S A
Lari A, Shah SB, Mao X, Sanghrajka P, Karijolich J, Lareau LF, Glaunsinger BA.   +6 more
europepmc   +1 more source

Advances in molecular regulation and function of LDLR family in viral infection. [PDF]

Front Microbiol
Yao Q, Gong J, Lu H, Liu W, Ding L.
europepmc   +1 more source