Results 101 to 110 of about 1,517 (162)
Requirement of MHV68 M2 protein for efficient reactivation from B cell latency.
, 2013 (A) Schematic illustration MHV68 recombinant viruses harboring a hygromycin phosphotransferase gene fused to EGFP (Hygro-EGFP) in the neutral locus of either wild type (WT-HE) or an M2-null mutant virus (M2.Stop-HE).
Neal N. Iwakoshi (369025) +4 more
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, 2014 (A) Schematic illustration depicting the v-cyclin locus and insertion of KSHV v-cyclin in place of the MHV68 v-cyclin open reading frame. (B) RL-65 cells were plated to confluency and then infected at an MOI of 0.05 with either WT MHV68, vCyclin.stop or ...
Francine M. Scott (546179) +1 more
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MHV68 infected lung epithelial cells express epithelial and mesenchymal cell markers in vivo.
, 2013 (A) Immunofluorescent staining of frozen lung sections of MHV68 infected IFNγR−/− mice at day 7. Virus antigen detection was performed using an anti-MHV68 polyclonal antibody (green).
Mauricio Rojas (173910) +8 more
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IFNγR-/- Balb/c mice are protected from MHV68 induced fibrosis.
, 2015 8–12 week old IFNγR-/- Balbc mice were intranasally infected with 1000 pfu MHV68 (WT or M1st) or mock were infected and sacrificed at 28 days post infection (n = 3 mice/group).
Cynthia L. Courtney (463498) +7 more
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OASL expression is beneficial for MHV68 and KSHV replication.
, 2018 (A-F, H) 293T OASL-/- cells were reconstituted with empty vector (EV), mOASL1, or hOASL as indicated. (A-B) 24 h later, cells were infected with VSV-GFP for 16 h. The GFP intensity in fixed cells was determined by flow cytometry.
Josef Wissing (28448) +13 more
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, 2013 Overview of integrated approach combining phosphoproteomics, bioinformatics, and biological tests to define signaling events that regulate MHV68 lytic replication.
Daniel E. Voth (196250) +6 more
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Expression of Twist is induced by in vitro infection of lung epithelial cells with MHV68.
, 2013 MLE-15 cells were mock-infected or infected at multiplicity of infection of 0.01 with MHV68 and analyzed 48 h post-infection for Twist expression. (A) Immunostaining of infected cells using an anti-Twist antibody.
Mauricio Rojas (173910) +8 more
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A non-MHV68 promoter escapes repression on the viral genome.
, 2020 (A) 293T cells were transfected with muSOX or a GFP control fused to the cell surface glycoprotein Thy1.1 with an intervening P2A ribosome skipping sequence.
Ileana M. Cristea (246789) +4 more
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IL-21 signaling is required for efficient establishment of MHV68 latency.
, 2015 Mice were infected intranasally with 1,000 pfu of MHV68-H2bYFP and splenocytes were harvested at the indicated time points. (A) Representative flow plots showing identification of YFP+ B cells at d16 post-infection.
Samuel H. Speck (70359) +1 more
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MHV68 results in the expansion of a unique T cell population, CD8dim.
, 2013 A) Flow cyotmetric plots showing CD8 versus CD3 staining after gating on lymphocytes by forward and side scatter followed by gating on CD3+/CD8+ cells. Flow cytometry was performed on peripheral blood samples drawn 6 weeks post-infection or in similarly ...
Danxia Duan (441626) +11 more
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