Results 91 to 100 of about 1,598 (170)
Targets of MHV68 miRNAs are repressed in vivo.
, 2019 The relative expression of endogenous mRNAs in non-infected versus infected B cells sorted from in vivo samples during chronic infection. Wild-type B6 mice were infected i.n. with 104 PFU of MHV68-H2bYFP.
Yiping Wang (1484218) +10 more
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, 2019 A. The top 15 canonical pathways enriched for targets of MHV68 miRNAs in either fibroblasts (left panel) or B cells (right panel). Bar graphs correspond with the top X-axes, and depict the percent of target transcripts that overlap (blue) with each ...
Yiping Wang (1484218) +10 more
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Latent infection with MHV68 results in abbreviated skin allograft survival.
, 2013 A) Kaplan-Meier survival curves showing skin graft survival for the following cohorts: Black solid line - Non-infected B6 recipients of BALB/C skin allografts, receiving CTLA-4-Ig+anti-CD154 CoB. N = 48, 8 independent experiments, MST 22 d.
Danxia Duan (441626) +11 more
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IRF4 is required for establishment of MHV68 latency as well as for reactivation from latency.
, 2014 IRF4fl/fl mice were infected with 1000 PFU of either MHV68-Cre or MHV68-WT virus intranasally. On day 16 post infection, splenocytes were analyzed by limiting dilution analyses to determine (A) the frequency of virus capable of establishing latency and ...
Samuel H. Speck (70359) +1 more
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, 2014 C57Bl/6 mice were infected via intranasal inoculation with 1,000 pfu of either WT MHV68, vCyclin.stop or a recombinant MHV68 expressing the KSHV v-cyclin from the MHV68 v-cyclin locus (K-cyclin).
Francine M. Scott (546179) +1 more
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The NC-specific B cell response in DR1 mice is modulated by concurrent infection with MHV68.
, 2012 (A–D) Virus-specific ASC frequencies. DR1 and B10 mice were infected intranasally with NC only, or with NC and MHV68. ASC frequencies in the MedLN were determined by ELISPOT assay on day 8 (A and B) and day 10 (C and D) after infection. ASCs specific for
Aarthi Sundararajan (175739) +10 more
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MHV68 miRNA targets extensively overlap with EBV and KSHV miRNA targets.
, 2019 A. Diagram indicates the number of unique host mRNA targets of MHV68 miRNAs identified in one, two or three biological replicates (out of three). B. Venn diagram indicates the number of host mRNA targets of MHV68 miRNAs (identified in at least two of ...
Yiping Wang (1484218) +10 more
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PLoS Pathogens, 2014 Reactivation of the gammaherpesviruses Epstein-Barr virus (EBV), Kaposi's sarcoma-associated herpesvirus (KSHV) and murine gammaherpesvirus 68 (MHV68) from latently infected B cells has been linked to plasma cell differentiation. We have previously shown
Udaya S Rangaswamy, Samuel H Speck
doaj +1 more source
MHV68 D-type cyclin ortholog enhances CDK-related phosphorylation in infected cells.
, 2013 (A) 3T3 fibroblasts were mock infected or infected with WT or transposon mutant (tn) MHV68 viruses at MOI = 5 PFU/cell. (B) Cells were mock infected or infected with v-cyclin-null (ORF72-null) or genetically repaired WT control (ORF72-MR) MHV68 ...
Daniel E. Voth (196250) +6 more
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Cell Reports, 2019 Summary: The gammaherpesviruses, including Epstein-Barr virus (EBV), Kaposi's sarcoma-associated herpesvirus (KSHV), and murine gammaherpesvirus 68 (MHV68, MuHV-4, γHV68), are etiologic agents of a wide range of lymphomas and non-hematological ...
Tina O’Grady +8 more
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