Results 71 to 80 of about 2,998 (132)

Vortioxetine‐induced syndrome of inappropriate secretion of antidiuretic hormone: A case report

Neuropsychopharmacology Reports
Background Vortioxetine, known for its efficacy in treating depression through its effects on various neurotransmitters, has not been previously reported to induce syndrome of inappropriate secretion of antidiuretic hormone (SIADH).
Taro Sasaki, Yunosuke Shindo, Kota Kikuchi, Yasushi Kawamata, Norio Sugawara, Norio Yasui‐Furukori   +5 more
doaj   +1 more source

Dm5-HT2B: Pharmacological Characterization of the Fifth Serotonin Receptor Subtype of Drosophila melanogaster

Frontiers in Systems Neuroscience, 2017
Serotonin (5-hydroxytryptamine, 5-HT) is an important regulator of physiological and behavioral processes in both protostomes (e.g., insects) and deuterostomes (e.g., mammals).
Wolfgang Blenau, Stöppler Daniel, Sabine Balfanz, Markus Thamm, Arnd Baumann   +4 more
doaj   +1 more source

Different pH-sensitivity patterns of 30 sodium channel inhibitors suggest chemically different pools along the access pathway.

Frontiers in Pharmacology, 2015
The major drug binding site of sodium channels is inaccessible from the extracellular side, drug molecules can only access it either from the membrane phase, or from the intracellular aqueous phase.
Alexandra eLazar, Nora eLenkey, Krisztina ePesti, Krisztina ePesti, Laszlo eFodor, Arpad eMike   +5 more
doaj   +1 more source

Concomitant medication, comorbidity and survival in patients with breast cancer

Nature Communications
Between 30% and 70% of patients with breast cancer have pre-existing chronic conditions, and more than half are on long-term non-cancer medication at the time of diagnosis.
Elise Dumas, Beatriz Grandal Rejo, Paul Gougis, Sophie Houzard, Judith Abécassis, Floriane Jochum, Benjamin Marande, Annabelle Ballesta, Elaine Del Nery, Thierry Dubois, Samar Alsafadi, Bernard Asselain, Aurélien Latouche, Marc Espie, Enora Laas, Florence Coussy, Clémentine Bouchez, Jean-Yves Pierga, Christine Le Bihan-Benjamin, Philippe-Jean Bousquet, Judicaël Hotton, Chloé-Agathe Azencott, Fabien Reyal, Anne-Sophie Hamy   +23 more
doaj   +1 more source

Computational approach to the prediction of blood-brain partitioning of basic drug candidates using mixed micellar liquid chromatography

مجله دانشگاه علوم پزشکی گرگان, 2017
Background and Objective: The blood–brain barrier (BBB) is considered to be the main barrier to drug transport into the central nervous system. In this study, the capability of biopartitioning micellar chromatography (BMC) using the mixed micellar system
S Arshadi
doaj  

Analgesic Efficacy and Tolerability of Amitriptyline versus Mianserin in Chronic Low Back Pain: A Randomised, Double-Blind, Controlled Pilot Trial. [PDF]

J Pain Res
Wangnamthip S, Eiamtanasate S, Saisavoey N, Sathienluckana T, Suthisiltham L, Panchoowong S, Tipapakoon I, Euasobhon P, Jensen MP, Srirojanakul W.   +9 more
europepmc   +1 more source

Unlocking neuronal health: leveraging C. elegans for drug repurposing studies. [PDF]

Cell Commun Signal
Gowda S, Kumar A, Topf U.
europepmc   +1 more source

Noradrenergic system involvement as a major driver of tension-type headache: a systematic review of the current evidence. [PDF]

J Headache Pain
Braca S, Cretella G, Deligianni C, Kennelly L, Tseriotis VS, Andreou AP, Mitsikostas DD, Mavridis T.   +7 more
europepmc   +1 more source

Enhanced inhibitory effects of mianserin in combination with sorafenib on liver cancer growth through targeting the CCR9-AKT pathway. [PDF]

Am J Cancer Res
Huang YH, Liao CJ, Wu MH, Lai MW, Yeh YH, Yeh CT, Lin YH, Lin KH.   +7 more
europepmc   +1 more source

Heterogeneous photocatalytic aldehyde alkylative amination for multicomponent synthesis of α-branched amines. [PDF]

Natl Sci Rev
Ou W, Xu Q, Wang Q, Tao Y, Wang J, Teng Z, Li F, Ding J, Liu W, Hou H, Yamakata A, Ohno T, Liu B, Su C.   +13 more
europepmc   +1 more source