Results 1 to 10 of about 15,444 (261)

Micafungin versus Amphotericin B in treatment of invasive fungal infection in preterm neonates: a randomized control trial [PDF]

Italian Journal of Pediatrics
Background Micafungin, Amphotericin B, and Fluconazole are the primary therapeutic agents employed to address invasive fungal candidiasis in neonates. Resistance to fluconazole is gradually developing in neonatal intensive care units. We aimed to conduct
Mariam John Amin Ibrahim, Marwa Saad Mohammed Fathy, Mertte Ashraf Thabet Ghobrial, Maha Hassan Mohamed   +3 more
doaj   +2 more sources

Ultrastructural and Immunohistochemical Study of Double and Combined Intravitreal Administration of Antifungal Agents in the Retina of New Zealand Albino Rabbits: An Experimental Protocol [PDF]

Journal of Fungi
Introduction: Fungal endophthalmitis (FE) is a rare but serious intraocular inflammatory disorder, resulting from an infection of the vitreous cavity from either endogenous or exogenous components that ultimately results in blindness.
Sofia Karachrysafi, Maria Kourti, Sophia Tsokkou, Despoina Ioannou, Evangelia Kofidou, Georgios Delis, Sotiris Sotiriou, Athanasios Karamitsos, Maria Xioteli, Ioanna Dori, Penelope Anastasiadou, Ioannis Konstantinidis, Dimitrios Kavvadas, Fotios Chatzinikolaou, Anastasia Komnenou, Vasileios Karampatakis, Antonia Sioga, Theodora Papamitsou   +17 more
doaj   +2 more sources

In vitro interactions of nystatin and micafungin combined with chlorhexidine against Candida albicans isolates [PDF]

Current Medical Mycology, 2022
Background and Purpose: Oral candidiasis has become a growing problem in hospitals worldwide, and the development of antifungal drug resistance in Candida species constitutes a serious concern.
Maede Salehi, Ali Malekzadeh Shafaroudi, Maryam Daryani, Alireza Khalilian, Fatemeh Ahangarkani, Tahere Molania   +5 more
doaj   +1 more source

Micafungin Inhibits Dengue Virus Infection through the Disruption of Virus Binding, Entry, and Stability

Pharmaceuticals, 2021
Dengue fever is an arbovirus disease caused by infection with the dengue virus (DENV). Half of the world’s population lives under the threat of dengue fever, however, researchers have yet to develop any drugs that are clinically applicable to this ...
Yen-Chen Chen, Jeng-Wei Lu, Chia-Tsui Yeh, Te-Yu Lin, Feng-Cheng Liu, Yi-Jung Ho   +5 more
doaj   +1 more source

Antiviral Activity of Micafungin and Its Derivatives against SARS-CoV-2 RNA Replication

Viruses, 2023
Echinocandin antifungal drugs, including micafungin, anidulafungin, and caspofungin, have been recently reported to exhibit antiviral effects against various viruses such as flavivirus, alphavirus, and coronavirus. In this study, we focused on micafungin
Shogo Nakajima, Hirofumi Ohashi, Daisuke Akazawa, Shiho Torii, Rigel Suzuki, Takasuke Fukuhara, Koichi Watashi   +6 more
doaj   +1 more source

A genome-wide screening of potential target genes to enhance the antifungal activity of micafungin in Schizosaccharomyces pombe. [PDF]

PLoS ONE, 2013
Micafungin is a non-reversible inhibitor of 1, 3-β-D-glucan synthase and interferes with fungal cell wall synthesis. Clinically, micafungin has been shown to be efficacious for the treatment of invasive candidiasis and invasive aspergillosis.
Xin Zhou, Yan Ma, Yue Fang, Wugan gerile, Wurentuya Jaiseng, Yuki Yamada, Takayoshi Kuno   +6 more
doaj   +1 more source

Assessment of Micafungin Dosage Regimens in Patients with Cancer Using Pharmacokinetic/Pharmacodynamic Modeling and Monte Carlo Simulation

Antibiotics, 2021
Micafungin is widely used for invasive candidiasis, especially in critically ill patients and those with cancer, and for empirical antifungal therapy in patients with neutropenic fever.
Saeed Alqahtani, Asma Alfarhan, Abdullah Alsultan, Emad Alsarhani, Abdulaziz Alsubaie, Yousif Asiri   +5 more
doaj   +1 more source

Effect of antifungal stewardship on micafungin prescribing practices in intensive care units at a tertiary-care hospital

Antimicrobial Stewardship & Healthcare Epidemiology, 2023
Background: Fungal diseases are associated with substantial global mortality and economic burden, especially in critically ill or immunocompromised patients.
Radhika Arya, Sarah Norman, Farah Daas, Sheena Ramdeen   +3 more
doaj   +1 more source

Characterizing Safety and Clinical Outcomes Associated with High-Dose Micafungin Utilization in Patients with Proven Invasive Candidiasis

Tropical Medicine and Infectious Disease, 2022
Micafungin is the empiric antifungal agent of choice for the treatment of invasive candidiasis (IC). Pathophysiologic changes that occur in obese and/or critically ill patients can alter micafungin serum concentrations and the probability of target ...
Victoria C. Grant, Kenneth Nguyen, Sasha Rodriguez, Anna Y. Zhou, Jacinda C. Abdul-Mutakabbir, Karen K. Tan   +5 more
doaj   +1 more source

Persistent candida arthritis successfully treated with micafungin instillation and surgery. A case report

Medical Mycology Case Reports, 2020
We report a rare case of C. krusei knee arthritis treated with instillation of micafungin and arthroscopy. A 49-year-old man hospitalized for treatment of Acute Myeloid Leukemia developed knee arthritis with C. krusei.
Jeroen C. van Egmond, Nicole G.M. Hunfeld, Bart J.A. Rijnders, Jan A.N. Verhaar   +3 more
doaj   +1 more source