Results 11 to 20 of about 9,079 (152)

Species Distribution of Candidemia and Their Susceptibility in a Single Japanese University Hospital: Prior Micafungin Use Affects the Appearance of Candida parapsilosis and Elevation of Micafungin MICs in Non-parapsilosis Candida Species

Journal of Fungi, 2021
Introduction: Micafungin is a recommended echinocandin antifungal agent for candidemia treatment and prophylaxis. However, overuse of echinocandin antifungals may cause resistance.
Yasutaka Sakamoto, Kazuhiro Kawabe, Tomoyo Suzuki, Kayoko Sano, Kazuo Ide, Tetsuta Nishigaki, Yuki Enoki, Kazuaki Taguchi, Hirofumi Koike, Hideaki Kato, Yukiko Sahashi, Kazuaki Matsumoto   +11 more
doaj   +1 more source

Plasma and Cerebrospinal Fluid Concentrations of Micafungin Administered at High Doses in Critically Ill Infants with Systemic Candidiasis: A Pooled Analysis of Two Studies

Pharmaceuticals, 2023
Background: Neonates may require higher doses of micafungin than adults to reach the therapeutic effect for increased plasma clearance. Only poor and inconclusive data are available still now to support this hypothesis, especially with regard to central ...
Domenico Umberto De Rose, Iliana Bersani, Maria Paola Ronchetti, Fiammetta Piersigilli, Sara Cairoli, Andrea Dotta, Amit Desai, Laura Lynn Kovanda, Bianca Maria Goffredo, Cinzia Auriti   +9 more
doaj   +1 more source

Postantifungal Effect of Micafungin against the Species Complexes of Candida albicans and Candida parapsilosis. [PDF]

PLoS ONE, 2015
Micafungin is an effective antifungal agent useful for the therapy of invasive candidiasis. Candida albicans is the most common cause of invasive candidiasis; however, infections due to non-C.
Sandra Gil-Alonso, Nerea Jauregizar, Elena Eraso, Guillermo Quindós   +3 more
doaj   +1 more source

Does DHN-Melanin Always Protect Fungi against Antifungal Drugs? The Fonsecaea/Micafungin Paradigm

Microbiology Research, 2022
Several human pathogenic fungi produce melanin. One of its properties during parasitism is the protection against antifungal drugs. This occurs with the agents of chromoblastomycosis, in which DHN-melanin reduces antifungal susceptibility to terbinafine ...
Rowena Alves Coelho, Maria Helena Galdino Figueiredo-Carvalho, Juliana Vitória dos Santos Silva, Dario Correa-Junior, Susana Frases, Rosely Maria Zancopé-Oliveira, Dayvison Francis Saraiva Freitas, Rodrigo Almeida-Paes   +7 more
doaj   +1 more source

Micafungin Effectiveness in Treating Pediatric Patients with Proven Candidemia

Journal of Pediatric Research, 2022
Aim:Micafungin is one of three currently available echinocandin for the treatment of candidiasis and candidemia. We aimed to discuss the effectiveness of micafungin and any possible side effects in the treatment of proven candidemia in children.Materials
Kamile Ötiken Arıkan, Oğuzhan Kalkanlı, Şebnem Çalkavur, Şeyma Akkuş, Mustafa Çolak, Elif Böncüoğlu, Elif Kıymet, Aybuke Akaslan Kara, Hasan Agın, Nuri Bayram, İlker Devrim   +10 more
doaj   +1 more source

Prospective Study on Prophylactic Micafungin Sodium against Invasive Fungal Disease during Neutropenia in Pediatric & Adolescent Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation

Children, 2022
Background: Invasive fungal diseases (IFDs) increase the mortality rate of patients with neutropenia who receive chemotherapy or have previously undergone hematopoietic stem cell transplantation (HSCT).
Bo-Kyung Kim, Jung-Yoon Choi, Kyung-Taek Hong, Hong-Yul An, Hee-Young Shin, Hyoung-Jin Kang   +5 more
doaj   +1 more source

Histological Effects of Intravitreal Injection of Antifungal Agents in New Zealand White Rabbits: An Electron Microscopic and Immunohistochemical Study

Pharmaceuticals, 2020
Fungal endophthalmitis is a serious and vision-threatening infection which requires an immediate and effective treatment approach. Our research aims to elucidate the histological effects of the intravitreal injection of the maximum safe dosage of ...
Sofia Karachrysafi, Antonia Sioga, Anastasia Komnenou, Athanasios Karamitsos, Maria Xioteli, Ioanna Dori, Georgios Delis, Evangelia Kofidou, Penelope Anastasiadou, Sotiris Sotiriou, Vasileios Karampatakis, Theodora Papamitsou   +11 more
doaj   +1 more source

Evaluation of an Antifungal Stewardship Initiative Targeting Micafungin at an Academic Medical Center

Antibiotics, 2023
Delays in the treatment of proven invasive fungal disease have been shown to be harmful. However, empiric treatment for all patients at risk of infection has not demonstrated benefit.
J. Myles Keck, David A. Cretella, Kayla R. Stover, Jamie L. Wagner, Katie E. Barber, Tulip A. Jhaveri, Prakhar Vijayvargiya, Zerelda Esquer Garrigos, Mary Joyce B. Wingler   +8 more
doaj   +1 more source

Assessing the effect of micafungin on Pseudomonas aeruginosa biofilm formation using confocal microscopy and gene expression

Journal of Infection in Developing Countries, 2018
Introduction: 1,3-β-D-glucan of the fungal cell wall and extracellular matrix (ECM) of Candida biofilm is also present as a periplasmic glucan and within the ECM of P. aeruginosa biofilm. Micafungin inhibits the synthesis of β-D-glucans.
Sari S Rasheed, Kohar Annie Kissoyan, Usamah Hadi, Marwan El-Sabban, Ghassan M Matar   +4 more
doaj   +1 more source

A case of bloodstream co-infection of Saccharomyces cerevisiae and Candida glabrata while using micafungin

BMC Infectious Diseases, 2023
Background Saccharomyces cerevisiae is ubiquitous in the gastrointestinal tract and known as brewer's or baker's yeast. We experienced a case of S. cerevisiae and Candida glabrata co-infectious bloodstream infection.
Kento Furuya, Kenta Ito, Kyohei Sugiyama, Satoshi Tokuda, Hideyuki Kanemoto, Katsuhiko Kamei, Toshio Shimada   +6 more
doaj   +1 more source