Results 21 to 30 of about 16,064 (238)

Micafungin Inhibits Dengue Virus Infection through the Disruption of Virus Binding, Entry, and Stability

Pharmaceuticals, 2021
Dengue fever is an arbovirus disease caused by infection with the dengue virus (DENV). Half of the world’s population lives under the threat of dengue fever, however, researchers have yet to develop any drugs that are clinically applicable to this ...
Yen-Chen Chen, Jeng-Wei Lu, Chia-Tsui Yeh, Te-Yu Lin, Feng-Cheng Liu, Yi-Jung Ho   +5 more
doaj   +1 more source

Prospective Study on Prophylactic Micafungin Sodium against Invasive Fungal Disease during Neutropenia in Pediatric & Adolescent Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation

Children, 2022
Background: Invasive fungal diseases (IFDs) increase the mortality rate of patients with neutropenia who receive chemotherapy or have previously undergone hematopoietic stem cell transplantation (HSCT).
Bo-Kyung Kim, Jung-Yoon Choi, Kyung-Taek Hong, Hong-Yul An, Hee-Young Shin, Hyoung-Jin Kang   +5 more
doaj   +1 more source

Biofilm-forming capability of highly virulent, multidrug-resistant Candida auris [PDF]

, 2017
The emerging multidrug-resistant yeast pathogen Candida auris has attracted considerable attention as a source of healthcare–associated infections. We report that this highly virulent yeast has the capacity to form antifungal resistant biofilms sensitive
Borman, Andrew, Johnson, Elizabeth M., Kean, Ryan, Ramage, Gordon, Rautemaa-Richardson, Riina, Richardson, Malcolm D., Sherry, Leighann   +6 more
core   +4 more sources

Hsp90 governs dispersion and drug resistance of fungal biofilms [PDF]

, 2011
Fungal biofilms are a major cause of human mortality and are recalcitrant to most treatments due to intrinsic drug resistance. These complex communities of multiple cell types form on indwelling medical devices and their eradication often requires ...
A Lupetti, A Viudes, C d'Enfert, CA Kumamoto, CJ Nobile, CJ Nobile, D Andes, D Shahinas, David Andes, E Mowat, EM Kojic, ET Burt, G Ramage, G Ramage, G Ramage, G Ramage, G Ramage, Gordon Ramage, J McCourtie, J Nett, J Trepel, JB Anderson, JC Young, JE Nett, Jeniel Nett, Jose L. Lopez-Ribot, JR Blankenship, JS Finkel, L Ostrosky-Zeichner, LE Cowen, LE Cowen, LE Cowen, LE Cowen, LE Cowen, Leah E. Cowen, LH Pearl, LS Wilson, M Taipale, MA Pfaller, MA Pfaller, MJ Seidler, ML Richard, MM McNeil, Nicole Robbins, P Perumal, P Uppuluri, P Uppuluri, P Uppuluri, P Uppuluri, P Uppuluri, PK Mukherjee, Priya Uppuluri, R Pallavi, Ranjith Rajendran, Robin Charles May, RS Shapiro, RS Shapiro, S Garcia-Sanchez, S Park, S Perea, SD Singh, SJ Lin, SL LaFayette, SM Noble, SV Balashov, SZ Usmani, TE Zaoutis, Y Kaneko, YS Kim, Z Odabasi   +69 more
core   +4 more sources

Evaluation of an Antifungal Stewardship Initiative Targeting Micafungin at an Academic Medical Center

Antibiotics, 2023
Delays in the treatment of proven invasive fungal disease have been shown to be harmful. However, empiric treatment for all patients at risk of infection has not demonstrated benefit.
J. Myles Keck, David A. Cretella, Kayla R. Stover, Jamie L. Wagner, Katie E. Barber, Tulip A. Jhaveri, Prakhar Vijayvargiya, Zerelda Esquer Garrigos, Mary Joyce B. Wingler   +8 more
doaj   +1 more source

Docking-based virtual screening of known drugs against murE of Mycobacterium tuberculosis towards repurposing for TB. [PDF]

, 2016
Repurposing has gained momentum globally and become an alternative avenue for drug discovery because of its better success rate, and reduced cost, time and issues related to safety than the conventional drug discovery process.
Brindha, Sridharan, Gnanadoss, John Joel, Sundaramurthi, Jagadish Chandrabose, Velmurugan, Devadasan, Vincent, Savariar   +4 more
core   +1 more source

Micafungin Effectiveness in Treating Pediatric Patients with Proven Candidemia

Journal of Pediatric Research, 2022
Aim:Micafungin is one of three currently available echinocandin for the treatment of candidiasis and candidemia. We aimed to discuss the effectiveness of micafungin and any possible side effects in the treatment of proven candidemia in children.Materials
Kamile Ötiken Arıkan, Oğuzhan Kalkanlı, Şebnem Çalkavur, Şeyma Akkuş, Mustafa Çolak, Elif Böncüoğlu, Elif Kıymet, Aybuke Akaslan Kara, Hasan Agın, Nuri Bayram, İlker Devrim   +10 more
doaj   +1 more source

A Randomized, Placebo-controlled Trial of Preemptive Antifungal Therapy for the Prevention of Invasive Candidiasis Following Gastrointestinal Surgery for Intra-abdominal Infections. [PDF]

, 2015
BACKGROUND: Patients undergoing emergency gastrointestinal surgery for intra-abdominal infection are at risk of invasive candidiasis (IC) and candidates for preemptive antifungal therapy.
Brown, M., Cornely, O.A., Dimopoulos, G., Dinya, T., Eggimann, P., François, B., Karas, A., Knitsch, W., León, C., Montravers, P., Phillips, S., Tweddle, L., Utzolino, S., Valía, J.C., Vincent, J.L., Özgüneş, İ.   +15 more
core   +1 more source

Treatment of Aspergillosis. [PDF]

, 2018
Infections caused by Aspergillus spp. remain associated with high morbidity and mortality. While mold-active antifungal prophylaxis has led to a decrease of occurrence of invasive aspergillosis (IA) in those patients most at risk for infection ...
Hoenigl, Martin, Jenks, Jeffrey D
core   +1 more source

Candida auris, what do paediatricians need to know? [PDF]

, 2018
AW is supported by the Wellcome Trust Strategic Award (grant 097377) and the MRC Centre for Medical Mycology (grant MR/N006364/1) at the University of Aberdeen.Peer reviewedPublisher ...
Warris, Adilia
core   +1 more source