Results 21 to 30 of about 17,905 (230)

Rapid Evolution of Multidrug Resistance in a Candida lusitaniae Infection during Micafungin Monotherapy

open access: yesAntimicrobial Agents and Chemotherapy, 2023
Candida (Clavispora) lusitaniae is a rare, emerging non-albicans Candida species that can cause life-threatening invasive infections, spread within hospital settings, and rapidly acquire antifungal drug resistance, including multidrug resistance.
N. E. Scott   +3 more
semanticscholar   +1 more source

Micafungin twice-a-week for prophylaxis of invasive Aspergillus infections in children with acute lymphoblastic leukaemia: a controlled cohort study.

open access: yesInternational Journal of Antimicrobial Agents, 2023
OBJECTIVES Invasive Aspergillus infections during the early phase of childhood acute lymphoblastic leukemia (ALL) treatment come with morbidity and mortality. The interaction with vincristine hampers first-line azole prophylaxis. We describe the efficacy
D. Bury   +6 more
semanticscholar   +1 more source

Effect of antifungal stewardship on micafungin prescribing practices in intensive care units at a tertiary-care hospital

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology, 2023
Background: Fungal diseases are associated with substantial global mortality and economic burden, especially in critically ill or immunocompromised patients.
Radhika Arya   +3 more
doaj   +1 more source

Persistent candida arthritis successfully treated with micafungin instillation and surgery. A case report

open access: yesMedical Mycology Case Reports, 2020
We report a rare case of C. krusei knee arthritis treated with instillation of micafungin and arthroscopy. A 49-year-old man hospitalized for treatment of Acute Myeloid Leukemia developed knee arthritis with C. krusei.
Jeroen C. van Egmond   +3 more
doaj   +1 more source

Serine/Threonine Phosphatase Calcineurin Orchestrates the Intrinsic Resistance to Micafungin in the Human-Pathogenic Fungus Mucor circinelloides

open access: yesAntimicrobial Agents and Chemotherapy, 2023
Procedures such as solid-organ transplants and cancer treatments can leave many patients in an immunocompromised state. This leads to their increased susceptibility to opportunistic diseases such as fungal infections.
Alexis García, E. Huh, Soo Chan Lee
semanticscholar   +1 more source

Micafungin for Candida infections in Slovenia and Romania: A multicenter, observational, prospective study

open access: yesJournal of Infection in Developing Countries, 2021
Introduction: An echinocandin, such as micafungin, is recommended as first-line treatment for invasive Candida infections in immunocompromised patients. This multicenter, observational, prospective, non- interventional study evaluated the real-world use
Samo Zver   +8 more
doaj   +1 more source

Comparison of In Vitro Killing Activity of Rezafungin, Anidulafungin, Caspofungin, and Micafungin against Four Candida auris Clades in RPMI-1640 in the Absence and Presence of Human Serum

open access: yesMicroorganisms, 2021
Candida auris is an emerging and frequently multidrug-resistant pathogen against which the echinocandins are the preferred therapeutic option. We compared killing activities of anidulafungin, caspofungin, micafungin, and rezafungin against 13 isolates ...
R. Kovács   +7 more
semanticscholar   +1 more source

Postantifungal Effect of Micafungin against the Species Complexes of Candida albicans and Candida parapsilosis. [PDF]

open access: yesPLoS ONE, 2015
Micafungin is an effective antifungal agent useful for the therapy of invasive candidiasis. Candida albicans is the most common cause of invasive candidiasis; however, infections due to non-C.
Sandra Gil-Alonso   +3 more
doaj   +1 more source

Biofilm-forming capability of highly virulent, multidrug-resistant Candida auris [PDF]

open access: yes, 2017
The emerging multidrug-resistant yeast pathogen Candida auris has attracted considerable attention as a source of healthcare–associated infections. We report that this highly virulent yeast has the capacity to form antifungal resistant biofilms sensitive
Borman, Andrew   +6 more
core   +4 more sources

Docking-based virtual screening of known drugs against murE of Mycobacterium tuberculosis towards repurposing for TB. [PDF]

open access: yes, 2016
Repurposing has gained momentum globally and become an alternative avenue for drug discovery because of its better success rate, and reduced cost, time and issues related to safety than the conventional drug discovery process.
Brindha, Sridharan   +4 more
core   +1 more source

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