Results 21 to 30 of about 19,208 (277)
Antimicrobial Agents and Chemotherapy, 2023 Candida (Clavispora) lusitaniae is a rare, emerging non-albicans Candida species that can cause life-threatening invasive infections, spread within hospital settings, and rapidly acquire antifungal drug resistance, including multidrug resistance.
N. E. Scott +3 more
semanticscholar +1 more source
Improving the production of the micafungin precursor FR901379 in an industrial production strain
Microbial Cell Factories, 2023 Background Micafungin is an echinocandin-type antifungal agent used for the clinical treatment of invasive fungal infections. It is semisynthesized from the sulfonated lipohexapeptide FR901379, a nonribosomal peptide produced by the filamentous fungus ...
P. Men +6 more
semanticscholar +1 more source
A genome-wide screening of potential target genes to enhance the antifungal activity of micafungin in Schizosaccharomyces pombe. [PDF]
PLoS ONE, 2013 Micafungin is a non-reversible inhibitor of 1, 3-β-D-glucan synthase and interferes with fungal cell wall synthesis. Clinically, micafungin has been shown to be efficacious for the treatment of invasive candidiasis and invasive aspergillosis.
Xin Zhou +6 more
doaj +1 more source
Antimicrobial Stewardship & Healthcare Epidemiology, 2023 Background: Fungal diseases are associated with substantial global mortality and economic burden, especially in critically ill or immunocompromised patients.
Radhika Arya +3 more
doaj +1 more source
Antimicrobial Agents and Chemotherapy, 2023 Procedures such as solid-organ transplants and cancer treatments can leave many patients in an immunocompromised state. This leads to their increased susceptibility to opportunistic diseases such as fungal infections.
Alexis García, E. Huh, Soo Chan Lee
semanticscholar +1 more source
Medical Mycology Case Reports, 2020 We report a rare case of C. krusei knee arthritis treated with instillation of micafungin and arthroscopy. A 49-year-old man hospitalized for treatment of Acute Myeloid Leukemia developed knee arthritis with C. krusei.
Jeroen C. van Egmond +3 more
doaj +1 more source
Microorganisms, 2021 Candida auris is an emerging and frequently multidrug-resistant pathogen against which the echinocandins are the preferred therapeutic option. We compared killing activities of anidulafungin, caspofungin, micafungin, and rezafungin against 13 isolates ...
R. Kovács +7 more
semanticscholar +1 more source
Journal of Infection in Developing Countries, 2021 Introduction: An echinocandin, such as micafungin, is recommended as first-line treatment for invasive Candida infections in immunocompromised patients. This multicenter, observational, prospective, non- interventional study evaluated the real-world use
Samo Zver +8 more
doaj +1 more source
Antimicrobial Agents and Chemotherapy, 2021 Limited data are available on the most appropriate dosing, efficacy, and safety of micafungin in neonates with invasive candidiasis (IC). This study evaluated plasma levels, efficacy, and safety of micafungin at a dose of 8 mg/kg daily for a mean of 13.3
C. Auriti +8 more
semanticscholar +1 more source
Journal of Fungi, 2021 Fungal cell wall receptors relay messages about the state of the cell wall to the nucleus through the Cell Wall Integrity Signaling (CWIS) pathway. The ultimate role of the CWIS pathway is to coordinate repair of cell wall damage and to restore normal ...
Samantha Reese +4 more
semanticscholar +1 more source