Results 41 to 50 of about 16,064 (238)

Combined antifungal resistance and biofilm tolerance: the global threat of Candida auris [PDF]

, 2019
The enigmatic yeast Candida auris has emerged over the last decade and rapidly penetrated our consciousness. The global threat from this multidrug-resistant yeast has generated a call to arms from within the medical mycology community.
Kean, Ryan, Ramage, Gordon
core   +2 more sources

Histological Effects of Intravitreal Injection of Antifungal Agents in New Zealand White Rabbits: An Electron Microscopic and Immunohistochemical Study

Pharmaceuticals, 2020
Fungal endophthalmitis is a serious and vision-threatening infection which requires an immediate and effective treatment approach. Our research aims to elucidate the histological effects of the intravitreal injection of the maximum safe dosage of ...
Sofia Karachrysafi, Antonia Sioga, Anastasia Komnenou, Athanasios Karamitsos, Maria Xioteli, Ioanna Dori, Georgios Delis, Evangelia Kofidou, Penelope Anastasiadou, Sotiris Sotiriou, Vasileios Karampatakis, Theodora Papamitsou   +11 more
doaj   +1 more source

Molecular monitoring of minimal residual disease in two patients with MLL-rearranged acute myeloid leukemia and haploidentical transplantation after relapse [PDF]

, 2012
This report describes the clinical courses of two acute myeloid leukemia patients. Both had MLL translocations, the first a t(10;11)(p11.2;q23) with MLL-AF10 and the second a t(11;19)(q23;p13.1) with MLL-ELL fusion.
Beyer, Jörg, Blau, Igor Wolfgang, Burmeister, Thomas, Friedrichs, Birte, Lachmann, Nils, Lohm, Gunnar, Marschalek, Rolf, Meyer, Claus, Molkentin, Mara, Schwartz, Stefan, Tietze-Bürger, Carola, Uharek, Lutz   +11 more
core   +1 more source

Portal Vein Thrombosis in a Preterm Newborn with Mutation of the MTHFR and PAI-1 Genes and Sepsis by Candida parapsilosis [PDF]

, 2016
Objective This report discusses the role of both congenital and acquired risk factors in the pathogenesis of portal vein thrombosis (PVT). Study Design We describe the clinical management and treatment of PVT in a preterm newborn with a homozygous ...
CIMADOR, Marcello, CORSELLO, Giovanni, GIUFFRE, Mario, Moceri, G., Serra, G., Verso, C.   +5 more
core   +1 more source

In Silico Identification and In Vitro Validation of Repurposed Compounds Targeting the RSV Polymerase

Microorganisms, 2023
Respiratory Syncytial Virus (RSV) is the top cause of infant hospitalization globally, with no effective treatments available. Researchers have sought small molecules to target the RNA-dependent RNA Polymerase (RdRP) of RSV, which is essential for ...
Eric Xu, Seohyun Park, Juan Calderon, Dongdong Cao, Bo Liang   +4 more
doaj   +1 more source

Transcriptome assembly and profiling of Candida auris reveals novel insights into biofilm-mediated resistance [PDF]

, 2018
Candida auris has emerged as a significant global nosocomial pathogen. This is primarily due to its antifungal resistance profile but also its capacity to form adherent biofilm communities on a range of clinically important substrates.
Ben-Ami, Berkow, Berkow, Bizerra, Bongomin, Borman, Borman, Calvo, Chatterjee, Chowdhary, Defosse, Denning, Dominguez, Fisher, Fonseca, Fox, Fu, Grahl, Haas, Hager, Hashemi, Hunter, Jeffery-Smith, Kean, Kean, Kean, Kean, Kempf, Kordalewska, Kordalewska, Larkin, Liu, Liu, Lockhart, Lohse, Martínez, Mukherjee, Naglik, Naglik, Nailis, Nobile, Perfect, Pierce, Rajendran, Rajendran, Rajendran, Ramage, Ramage, Ramage, Rodrigues, Ruiz-Gaitán, Schelenz, Sherry, Sherry, Silva, Soldini, Taff, Taff, Tumbarello, Tunney, Winter, Zarnowski, Zhao, Zhao   +63 more
core   +4 more sources

PHARMACOECONOMIC ANALYSIS OF MICAFUNGIN USING IN THE TREATMENT OF INVASIVE CANDIDIASIS IN NEWBORNS

Педиатрическая фармакология, 2011
Invasive candidiasis is a common cause of neonatal sepsis, especially in children with very low birth weight. This study, for the first time in the world of medical research, shows the results of the clinico-economical expertise of using micafungin to ...
A.S. Kolbin, M.A. Proskurin, Yu.A. Balykina, N.N. Klimko   +3 more
doaj   +2 more sources

Echinocandin Resistance in Two Candida haemulonii Isolates from Pediatric Patients [PDF]

, 2012
We report 3 cases of patients with Candida haemulonii isolates that were obtained from hemocultures. in 2 of the 3 cases, isolates exhibited resistance to echinocandins and fluconazole.
Azevedo Melo, Analy Salles de, Burger, Marion, Dalla-Costa, Libera Maria, Motta, Fabio de Araujo, Muro, Marisol Dominguez   +4 more
core   +1 more source

Electronic health records improve the diagnosis and prognosis of pulmonary fungal infections in lung cancer patients

VIEW, EarlyView.
Pulmonary fungal infections are life‐threatening complications in lung cancer patients, posing significant challenges in clinical management. To address this, we developed machine learning tools that translate routine electronic health record data into actionable insights for diagnosing infections and assessing prognosis.
Hongwei Meng, Jiayun Yang, Shouzhi Yang, Ayizekeranmu Yiming, Wenjun Yu, Yuewei Zhao, Chunmeng Ding, Kexin Meng, Si Gao, Yang Li, Nan Dan, Dandan Feng, Yunhua Xu, Lin Huang, Yongxia Qiao   +14 more
wiley   +1 more source

Micafungin-Induced Suicidal Erythrocyte Death

Cellular Physiology and Biochemistry, 2016
Background/Aims: The antifungal drug Micafungin is used for the treatment of diverse fungal infections including candidiasis and aspergillosis. Side effects of Micafungin treatment include microangiopathic hemolytic anemia and thrombocytopenia with ...
Thomas Peter, Rosi Bissinger, Elena Signoretto, Andreas F. Mack, Florian Lang   +4 more
doaj   +1 more source