Results 61 to 70 of about 11,159 (187)

Probable Tigecycline‐Induced Acute Eosinophilic Pneumonia: A Case Report

Respirology Case Reports, Volume 14, Issue 8, August 2026.
A 25‐year‐old man developed acute hypoxaemic respiratory failure after 21 days of tigecycline therapy for osteomyelitis caused by multidrug‐resistant organisms. Although the clinical response followed multiple simultaneous interventions and therefore does not establish causality, the overall findings support tigecycline as the probable causative agent.
Annette Eom, Mutsumi Kioka
wiley   +1 more source

Retrospective cohort study comparing the risk of severe hepatotoxicity in hospitalized patients treated with echinocandins for invasive candidiasis in the presence of confounding by indication

BMC Infectious Diseases, 2018
Background To compare the risk of severe hepatotoxicity with anidulafungin versus caspofungin and micafungin in hospitalized adults. Methods This retrospective cohort study combined data from two large US- based hospital electronic medical record ...
Francis Vekeman, Lisa Weiss, Jalal Aram, Raluca Ionescu-Ittu, Shahrzad Moosavi, Yongling Xiao, Wendy Y. Cheng, Rachel H. Bhak, Margaret Tawadrous, M. Rita Capparella, Philippe Montravers, Mei Sheng Duh   +11 more
doaj   +1 more source

Development of Candidaemia Score (CanDi‐Score) in Decision of Early Empirical Antifungal Treatment for Patients in Intensive Care Unit: The International Prospective Observational ID‐IRI Study

Mycoses, Volume 69, Issue 8, August 2026.
ABSTRACT Background Candidaemia remains a common, life‐threatening infection among intensive care unit (ICU) patients, with high mortality, particularly in patients with delayed diagnosis and treatment. Objectives This international, multicentre, prospective, observational study aimed to identify risk factors for candidaemia in ICU patients and to ...
Bircan Kayaaslan, Halime Araz, Hatice Yağmur Zengin, Rukiyye Bulut, Zeynep Oktay, Meltem Tasbakan, Sumeyra Istek, Elif Doyuk Kartal, Ozlem Bayrak, Ayse Kaya, Fatma Eser, Pınar Yuruk Atasoy, Hatice Esranur Kıratlı, Berfin Cirkin Doruk, Mustafa Uguz, Sema Sarı, Bahar Busra Sivrikaya, Yasemin Akkoyunlu, Lutfiye Nilsun Altunal, Ayse Albayrak, Handan Alay, Gulsen Iskender, Elkholy Amani, Taylan Onder, Dilek Ozcengiz, Mediha Turktan, Mihalj Mirko, Ilad Alavi Darazam, Mohammad Mehdi Shadravan, Reza Yahyavi Sahzabi, Ahmet Cem Yardımcı, Ruveyda Korkmazer, Gunes Senol, Tuba Kuruoglu, Fatih Temocin, Ozlem Alıcı, Meral Sonmezoglu, Aliye Esmaoglu, Zeynep Ture, Andrea Cortegiani, Ozay Akyıldız, Hatice Rahmet Guner, Hakan Erdem   +42 more
wiley   +1 more source

Coagulation dysfunction events associated with echinocandins: a real-world study from FDA adverse event reporting system (FAERS) database

Thrombosis Journal
Background Echinocandins belong to the fourth generation of antifungals, and there are no systematic studies on their risk in coagulation dysfunction; this study will predict the risk of coagulation dysfunction of echinocandins using the US Food and Drug
Qian Cheng, Ye Wu, Zeyu Yao, Mengling Ouyang, Shupeng Zou, Xuan Shi, Yazheng Zhao, Minghui Sun   +7 more
doaj   +1 more source

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

Advanced Science, Volume 13, Issue 41, 22 July 2026.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai, Adrielle Xianwen Chen, Eve Wai Ling Chow, Li Mei Pang, Jianguo Li, Chandra Shekhar Verma, Stefan H. Oehlers, Yue Wang, Ning Li   +8 more
wiley   +1 more source

Micafungin in vitro aktivitása több mint 300 darab, különböző betegekből származó candida izolátum ellen

, 2010
A Candida genus speciesei közül a legjelentősebb a C. albicans, mert ez okoz leggyakrabban opportunista fertőzéseket emberekben, melyeknek a száma napjainkban fokozatosan nő.
Domán, Marianna
core  

An immunomodulatory activity of micafungin in preclinical aspergillosis

, 2014
Objectives: Micafungin inhibits 1,3-b-D-glucan synthase and interferes with fungal cell wall synthesis. Clinically, micafungin has been shown to be efficacious for the treatment of invasive fungal infections.
AVERSA, Franco, Prezioso, L, Romani, L, Moretti, S, Rossetti, E, Pitzurra, L., Bozza, S, Massi Benedetti, C   +7 more
core   +1 more source

Combination of Systemic and Lock-Therapies with Micafungin Eradicate Catheter-Based Biofilms and Infections Caused by Candida albicans and Candida parapsilosis in Neutropenic Rabbit Models

Journal of Fungi
Vascular catheter-related infections, primarily caused by Candida albicans and Candida parapsilosis, pose significant challenges due to the formation of biofilms on catheters, leading to refractory disease and considerable morbidity.
Ruta Petraitiene, Vidmantas Petraitis, Myo H. Zaw, Kaiser Hussain, Rodolfo J. Ricart Arbona, Emanuel Roilides, Thomas J. Walsh   +6 more
doaj   +1 more source

Cost Analysis of the Use of Voriconazole, Posaconazole and Micafungin in the Primary Prophylaxis of Invasive Fungal Infections in Recipients of Allogeneic Hematopoietic Stem Cell Transplants

Journal of Health Economics and Outcomes Research, 2015
# Objectives Compare the cost of the primary prophylaxis of invasive fungal infections (IFI) with voriconazole, posaconazole, and micafungin in patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT) in hospitals of the National ...
Santiago Grau, Carlos Solano, Carol García-Vidal, Isidro Jarque, Jon A. Barrueta, Carmen Peral, Irene Rodríguez, Darío Rubio-Rodríguez, Carlos Rubio-Terrés   +8 more
doaj   +1 more source

Susceptibility of the Candida haemulonii Complex to Echinocandins: Focus on Both Planktonic and Biofilm Life Styles and a Literature Review

Journal of Fungi, 2020
Candida haemulonii complex (C. haemulonii, C. duobushaemulonii and C. haemulonii var. vulnera) is well-known for its resistance profile to different available antifungal drugs.
Lívia S. Ramos, Laura N. Silva, Marta H. Branquinha, André L. S. Santos   +3 more
doaj   +1 more source