Results 51 to 60 of about 17,905 (230)

Variability in antifungal and antiviral use in hospitalized children [PDF]

, 2017
We analyzed antifungal and antiviral prescribing among high-risk children across freestanding children’s hospitals. Antifungal and antiviral days of therapy varied across hospitals.
Gerber, Jeffrey S, Goldman, Jennifer L, Hersh, Adam L, Kronman, Matthew P, Lee, Brian R, Newland, Jason G, Ross, Rachael K   +6 more
core   +2 more sources

Association of Doses Based on Body Constitutional Parameters with the Efficacy of Micafungin in Candidemia.

Journal of Infection and Chemotherapy
BACKGROUND Invasive candidiasis is a life-threatening infection associated with high mortality, necessitating early and effective treatment. Micafungin, an echinocandin, is recommended as initial therapy for invasive candidiasis.
Masaya Nagamizu, Yuji Hotta, Masato Noda, Daigaku Nakamura, Masayuki Hori, Yuto Otsuka, Ryuhei Takemoto, Yasuhiro Horita, Eri Wakita, Nobuyuki Morishita, Masahiro Kondo, Yoko Furukawa-Hibi, Kazunori Kimura   +12 more
semanticscholar   +1 more source

Nebulized Micafungin Treatment for Scopulariopsis/Microascus Tracheobronchitis in Lung Transplant Recipients

Antimicrobial Agents and Chemotherapy, 2021
Scopulariopsis/Microascus isolates cause infections with high mortality in lung transplant recipients. Treatment is challenging due to antimicrobial resistance.
I. Los-Arcos, C. Berastegui, M. Martín-Gómez, S. Grau, D. Campany-Herrero, M. Deu, J. Sacanell, N. Campillo, C. Bravo, Ò. Len   +9 more
semanticscholar   +1 more source

Can Intravenous Antifungal therapy be safely used in the Outpatient Parenteral Antimicrobial Therapy (OPAT) setting? [PDF]

, 2019
Outpatient parenteral antimicrobial therapy (OPAT) is an established treatment option for patients with a variety of infections who require a period of intravenous therapy, are clinically stable, and do not require continuous monitoring.
Kenny, Claire, Muldoon, Eavan G., Rae, Nikolas   +2 more
core   +2 more sources

Assessing the effect of micafungin on Pseudomonas aeruginosa biofilm formation using confocal microscopy and gene expression

Journal of Infection in Developing Countries, 2018
Introduction: 1,3-β-D-glucan of the fungal cell wall and extracellular matrix (ECM) of Candida biofilm is also present as a periplasmic glucan and within the ECM of P. aeruginosa biofilm. Micafungin inhibits the synthesis of β-D-glucans.
Sari S Rasheed, Kohar Annie Kissoyan, Usamah Hadi, Marwan El-Sabban, Ghassan M Matar   +4 more
doaj   +1 more source

Portal Vein Thrombosis in a Preterm Newborn with Mutation of the MTHFR and PAI-1 Genes and Sepsis by Candida parapsilosis [PDF]

, 2016
Objective This report discusses the role of both congenital and acquired risk factors in the pathogenesis of portal vein thrombosis (PVT). Study Design We describe the clinical management and treatment of PVT in a preterm newborn with a homozygous ...
CIMADOR, Marcello, CORSELLO, Giovanni, GIUFFRE, Mario, Moceri, G., Serra, G., Verso, C.   +5 more
core   +1 more source

Candida glabrata hospital isolate from Lebanon reveals micafungin resistance associated with increased chitin and resistance to a cell surface disrupting agent.

Journal of Global Antimicrobial Resistance
OBJECTIVES The aim of this study was to identify the resistance mechanisms to micafungin and fluconazole in a clinical isolate of Candida glabrata. METHODS The isolate was whole genome sequenced in order to identify amino acid changes in key proteins ...
Nour Fattouh, R. Khalaf, R. Husni
semanticscholar   +1 more source

Micafungin Is an Efficient Treatment of Multi Drug-Resistant Candida glabrata Urosepsis: A Case Report

Journal of Fungi, 2021
Candiduria is a common nosocomial infection in hospitalized patients, which may progress into life-threatening candidemia. Successful treatment of urosepsis requires early and effective antifungal therapy, while the available agents within three ...
Zuzana Javorova Rihova, L. Slobodova, A. Hrabovská   +2 more
semanticscholar   +1 more source

Molecular monitoring of minimal residual disease in two patients with MLL-rearranged acute myeloid leukemia and haploidentical transplantation after relapse [PDF]

, 2012
This report describes the clinical courses of two acute myeloid leukemia patients. Both had MLL translocations, the first a t(10;11)(p11.2;q23) with MLL-AF10 and the second a t(11;19)(q23;p13.1) with MLL-ELL fusion.
Beyer, Jörg, Blau, Igor Wolfgang, Burmeister, Thomas, Friedrichs, Birte, Lachmann, Nils, Lohm, Gunnar, Marschalek, Rolf, Meyer, Claus, Molkentin, Mara, Schwartz, Stefan, Tietze-Bürger, Carola, Uharek, Lutz   +11 more
core   +1 more source

In Silico Identification and In Vitro Validation of Repurposed Compounds Targeting the RSV Polymerase

Microorganisms, 2023
Respiratory Syncytial Virus (RSV) is the top cause of infant hospitalization globally, with no effective treatments available. Researchers have sought small molecules to target the RNA-dependent RNA Polymerase (RdRP) of RSV, which is essential for ...
Eric Xu, Seohyun Park, Juan Calderon, Dongdong Cao, Bo Liang   +4 more
doaj   +1 more source