Results 71 to 80 of about 15,444 (261)

Resistance in Candida albicans: exploring the cell wall barrier by proteomics [PDF]

, 2015
The incidence of candidiasis has dramatically increased and bloodstream infections due to different species of Candida are becoming a prime cause of morbidity and mortality in different types of immunocompromised patients.
Angiolella, Letizia, Maras, Bruno, Mignogna, Giuseppina   +2 more
core   +1 more source

Review of the pharmacology and clinical studies of micafungin

Drug Design, Development and Therapy, 2009
Micafungin, like other members of the echinocandin class, has a unique mechanism of action that inhibits the synthesis of 1,3-beta-D glucans in the fungal cell wall. It has been approved for treatment of esophageal candidiasis, invasive candidiasis including candidemia, and for prophylaxis of Candida infections in patients undergoing hematopoietic stem
Alison M. Bormann, Vicki A Morrison
openaire   +4 more sources

Evaluating Prescriber Adherence to Guideline-Based Treatment Pathways of a Newly Initiated Antimicrobial Stewardship Program at a Rehabilitation Hospital [PDF]

, 2017
Background: Inappropriate use of antimicrobials in the healthcare setting is associated with consequences including antimicrobial resistance, Clostridium difficile infection (CDI), adverse drug reactions, and increased healthcare costs.
Bertram, Christie
core   +1 more source

Disease Control and Manageable Toxicity With Epcoritamab in Refractory Diffuse Large B‐Cell Lymphoma‐Type Richter Syndrome: A Case Report in an Elderly Patient

Cancer Reports, Volume 8, Issue 9, September 2025.
ABSTRACT Background Richter syndrome (RS) is an aggressive transformation of chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) with poor prognosis. No standard treatment for RS has been established. Epcoritamab, a CD3xCD20 bispecific antibody, may offer clinical benefit.
Takumi Nishikawa, Masuho Saburi, Shogo Urabe, Eiichi Ohtsuka   +3 more
wiley   +1 more source

Genotyping and antifungal susceptibility of Dipodascus capitatus isolated in a neonatal intensive care unit of a sicilian hospital [PDF]

, 2017
In August 2015, Dipodascus capitatus was isolated from two patients admitted to the neonatal intensive care unit. Nosocomial acquisition of the fungus was suspected and epidemiological studies were undertaken.
Aquilina, G., Cal\ue0, C., Capra, G., Corsello, G., Fasciana, T., Giammanco, A, Giuffr\ue8, M., Lipari, D., Pinello, G., Schierz, I.   +9 more
core   +1 more source

Real World Incidence and Etiology of Infectious Complications in Adults With Ph‐Negative Acute Lymphoblastic Leukemia Treated With the Pediatric‐Inspired GIMEMA LAL1913 Program. A Campus All Study

Hematological Oncology, Volume 43, Issue 5, September 2025.
ABSTRACT Infections often complicate pediatric‐inspired treatments for adult Philadelphia‐negative acute lymphoblastic leukemia (Ph‐ ALL). Literature data on these complications are difficult to interpret due to the heterogeneity of types of infections analyzed or patients and treatment characteristics.
Patrizia Zappasodi, Ludovica Calabretta, Virginia Valeria Ferretti, Davide Lazzarotto, Nicola Fracchiolla, Marco Cerrano, Cristina Papayannidis, Sabina Chiaretti, Maria Ilaria Del Principe, Valentina Mancini, Monia Lunghi, Fabio Forghieri, Sara Mastaglio, Michelina Dargenio, Crescenza Pasciolla, Carla Mazzone, Beatrice Sani, Fabio Guolo, Marzia Defina, Maria Ciccone, Elisa Roncoroni, Marianna Rossi, Claudia Patricia Tobar Cabrera, Gianluca Martini, Giacomo Riccaboni, Luca Arcaini, Robin Foà, Anna Candoni   +27 more
wiley   +1 more source

Recent Insights into the Paradoxical Effect of Echinocandins

Journal of Fungi, 2017
Echinocandin antifungals represent one of the most important drug classes for the treatment of invasive fungal infections. The mode of action of the echinocandins relies on inhibition of the β-1,3-glucan synthase, an enzyme essentially required for the ...
Johannes Wagener, Veronika Loiko
doaj   +1 more source

Candida infections, causes, targets and resistance mechanisms. Traditional and alternative antifungal agents [PDF]

, 2013
The genus Candida includes about 200 different species, but only a few species are human opportunistic pathogens and cause infections when the host becomes debilitated or immunocompromised. Candida infections can be superficial or invasive.
Leonardi, Darío, Spampinato, Claudia Patricia   +1 more
core   +3 more sources

A Case Report of Chlamydia Psittaci Pneumonia and Pulmonary Aspergillosis Diagnosed by Nanopore Sequencing

iLABMED, Volume 3, Issue 3, Page 258-262, September 2025.
ABSTRACT This paper reports a case of Chlamydia psittaci pneumonia and pulmonary aspergillosis with concurrent liver injury. The patient was admitted to the hospital with coughing, expectoration, and fever for 5 days. Laboratory tests upon admission revealed abnormalities in liver function.
Chang Song, Chunyan Zhao, Aichun Huang, Chaoyan Xu, Chunmei Zeng, Qingdong Zhu   +5 more
wiley   +1 more source

A Prospective Surveillance Study of Candidaemia : Epidemiology, Risk Factors, Antifungal Treatment and Outcome in Hospitalized Patients [PDF]

, 2016
Funding This work was supported by the Wellcome Trust Strategic Award for Medical Mycology and Fungal Immunology 097377/Z/11/Z. Data collection was supported by a grant from Pfizer.
Deshpande, Ashutosh, Hanson, Mary F., Johnson, Elizabeth M., Jones, Brian L., Munro, Carol A., Rajendran, Ranjith, Ramage, Gordon, Sherry, Leighann, Williams, Craig   +8 more
core   +2 more sources