Results 81 to 90 of about 19,208 (277)
T‐cell large granular lymphocytic leukemia (T‐LGLL) is an uncommon lymphoproliferative disorder that typically follows a slow clinical course. Symptoms often remain subtle until cytopenia or infection develops. Severe infection secondary to neutropenia represents the major cause of mortality.
Yoshiki Uemura +3 more
wiley +1 more source
Candida haemulonii complex (C. haemulonii, C. duobushaemulonii and C. haemulonii var. vulnera) is well-known for its resistance profile to different available antifungal drugs.
Lívia S. Ramos +3 more
doaj +1 more source
Genotyping and antifungal susceptibility of Dipodascus capitatus isolated in a neonatal intensive care unit of a sicilian hospital [PDF]
In August 2015, Dipodascus capitatus was isolated from two patients admitted to the neonatal intensive care unit. Nosocomial acquisition of the fungus was suspected and epidemiological studies were undertaken.
Aquilina, G. +9 more
core +1 more source
Candida albicans and Staphylococcus aureus are pathogens commonly isolated from bloodstream infections worldwide. While coinfection by both pathogens is associated with mixed biofilms and more severe clinical manifestations, due to the combined ...
Gaby Scheunemann +3 more
doaj +1 more source
Challenges in optimizing tacrolimus therapy in patients treated with rifampin: A case series
Tacrolimus is a cornerstone immunosuppressant in transplantation medicine with a narrow therapeutic window. Drug–drug interactions with strong CYP3A4 and P‐glycoprotein modulators, such as rifampin and azole antifungals, significantly alter tacrolimus exposure and complicate therapy. Two transplant cases illustrates the impact of rifampin on tacrolimus
Jeroen P. A. Houwen +6 more
wiley +1 more source
Evaluating Prescriber Adherence to Guideline-Based Treatment Pathways of a Newly Initiated Antimicrobial Stewardship Program at a Rehabilitation Hospital [PDF]
Background: Inappropriate use of antimicrobials in the healthcare setting is associated with consequences including antimicrobial resistance, Clostridium difficile infection (CDI), adverse drug reactions, and increased healthcare costs.
Bertram, Christie
core +1 more source
Resistance in Candida albicans: exploring the cell wall barrier by proteomics [PDF]
The incidence of candidiasis has dramatically increased and bloodstream infections due to different species of Candida are becoming a prime cause of morbidity and mortality in different types of immunocompromised patients.
Angiolella, Letizia +2 more
core +1 more source
Treatment for chronic to invasive pulmonary aspergillosis typically involves azole antifungal drugs, although studies have shown varying minimum inhibitory concentrations (MIC) for these medications, with a growing concern over voriconazole resistance.
Aishwarya Nikhil +8 more
wiley +1 more source
Recent Insights into the Paradoxical Effect of Echinocandins
Echinocandin antifungals represent one of the most important drug classes for the treatment of invasive fungal infections. The mode of action of the echinocandins relies on inhibition of the β-1,3-glucan synthase, an enzyme essentially required for the ...
Johannes Wagener, Veronika Loiko
doaj +1 more source
Fungal DNA‐barcoding on a chip: Magnetoresistive biosensors for yeast infection diagnosis
The development of a fungal pathogen identification chip is herein demonstrated. Hybridization dynamics were tested against 58 species in silico and 4 species on chip. 95% accuracy, 91% sensitivity, 98% specificity and femtomolar limit of detection were achieved. Future perspectives include the integration of sample pre‐treatment modules.
Maria Zolotareva +8 more
wiley +1 more source

