Results 81 to 90 of about 11,994 (242)

Population pharmacokinetics of micafungin over repeated doses in critically ill patients: a need for a loading dose?

The Journal of pharmacy and pharmacology, 2020
To study the population pharmacokinetics of micafungin in critically ill patients, evaluate and optimize dosage regimens.
I. Kapralos, E. Mainas, E. Neroutsos, Stella Apostolidi, M. Siopi, O. Apostolopoulou, G. Dimopoulos, H. Sambatakou, G. Valsami, J. Meletiadis, A. Dokoumetzidis   +10 more
semanticscholar   +1 more source

Coccidioidomycosis Prophylaxis in Liver, Kidney, and Heart Transplant Recipients Residing in Endemic Areas Within the United States

Transplant Infectious Disease, Volume 27, Issue 2, March/April 2025.
Our data suggests that abdominal organ transplant recipients residing in CM‐endemic areas with no prior CM exposure may not require CM prophylaxis. Therefore, we recommend implementing a shared decision‐making model among healthcare providers and patients for this lower‐risk patient population.
Faiza Morado, Roland Davoudi, Rachel Cartus, Pnada Kawewat‐Ho, Apurva Akkad, Suhail A. Shaikh   +5 more
wiley   +1 more source

Fungal infections today: size of the problem and focus on the initial cost of therapy with echinocandin

Farmeconomia: Health Economics and Therapeutic Pathways, 2010
Three candins had been approved for the treatment of invasive candidiasis (IC): caspofungin, micafungin, and anidulafungin. Different drugs are associated with different needs for dose adjustment which might affect the total cost.
Mario Venditti
doaj   +1 more source

Pharmacokinetics of micafungin in patients treated with extracorporeal membrane oxygenation: an observational prospective study

Revista Brasileira de Terapia Intensiva, 2020
Objective To determine micafungin plasma levels and pharmacokinetic behavior in patients treated with extracorporeal membrane oxygenation. Methods The samples were taken through an access point before and after the membrane in two tertiary hospitals in ...
M. López‐Sánchez, Ignacio Moreno-Puigdollers, M. I. Rubio-López, Iratxe Zarragoikoetxea-Jauregui, R. Vicente-Guillén, María Pilar Argente-Navarro   +5 more
semanticscholar   +1 more source

Fungal Biomolecules for Food and Pharmaceutical Application

eFood, Volume 6, Issue 1, February 2025.
The review summarizes the diverse roles of fungal biomolecules in the food and pharmaceutical industries and highlights their significant contribution to modern medicine and health‐related fields. ABSTRACT Mushrooms have long been an integral part of human culture and health and are valued for their nutritional and therapeutic properties.
Giancarlo Angeles Flores, Gaia Cusumano, Gokhan Zengin, Roberto Venanzoni, Paola Angelini   +4 more
wiley   +1 more source

Recent Insights into the Paradoxical Effect of Echinocandins

Journal of Fungi, 2017
Echinocandin antifungals represent one of the most important drug classes for the treatment of invasive fungal infections. The mode of action of the echinocandins relies on inhibition of the β-1,3-glucan synthase, an enzyme essentially required for the ...
Johannes Wagener, Veronika Loiko
doaj   +1 more source

Anidulafungin and Micafungin Concentrations in Cerebrospinal Fluid and in Cerebral Cortex

Antimicrobial Agents and Chemotherapy, 2020
Anidulafungin and micafungin were quantified in cerebrospinal fluid (CSF) of critically ill adults and in cerebral cortex of deceased patients. In CSF, anidulafungin levels (
J. Marx, R. Welte, Tiziana Gasperetti, P. Moser, R. Beer, M. Ortler, M. Jeske, R. Stern, A. Pomaroli, M. Joannidis, R. Bellmann   +10 more
semanticscholar   +1 more source

Relapsed Philadelphia chromosome‐positive B‐cell acute lymphoblastic leukaemia responds well to a combination of modified hyper‐CVAD, blinatumomab and tyrosine kinase inhibitor

eJHaem, Volume 6, Issue 1, February 2025.
Abstract Introduction Adults with relapsed or refractory Philadelphia chromosome‐positive B‐cell precursor acute lymphoblastic leukaemia (R/R Ph+ BCP‐ALL) have a dismal outcome. Blinatumomab as a single agent has shown activity in R/R Ph‐ BCP‐ALL, and second or third‐generation tyrosine kinase inhibitors (TKIs) can produce high remission rates in Ph ...
Gaétan Basile, Jean Galtier, Titouan Cazaubiel, Edouard Forcade, Emilie Klein, Audrey Bidet, Carmen Botella‐Garcia, Clémence Mediavilla, Laurence Clement, Pierre‐Yves Dumas, Arnaud Pigneux, Thibaut Leguay   +11 more
wiley   +1 more source

Coagulation dysfunction events associated with echinocandins: a real-world study from FDA adverse event reporting system (FAERS) database

Thrombosis Journal
Background Echinocandins belong to the fourth generation of antifungals, and there are no systematic studies on their risk in coagulation dysfunction; this study will predict the risk of coagulation dysfunction of echinocandins using the US Food and Drug
Qian Cheng, Ye Wu, Zeyu Yao, Mengling Ouyang, Shupeng Zou, Xuan Shi, Yazheng Zhao, Minghui Sun   +7 more
doaj   +1 more source

Synergistic effect of nikkomycin Z with caspofungin and micafungin against Candida albicans and Candida parapsilosis biofilms

Letters in Applied Microbiology, 2019
Antifungal lock therapy has received significant interest in the last few years because the frequently usage of intravascular devices is associated with an increasing number of catheter‐related bloodstream infections caused by Candida species. Antifungal
R. Kovács, F. Nagy, Zoltán Tóth, Aliz Bozó, Bence Balázs, L. Majoros   +5 more
semanticscholar   +1 more source