Results 71 to 80 of about 90,588 (222)

Effect of dietary cholesterol and taurocholate on cholesterol 7 alpha-hydroxylase and hepatic LDL receptors in inbred mice

Journal of Lipid Research, 1993
Compared to BALB/c mice, inbred C57BL/6 mice are more susceptible to developing fatty streak atherosclerotic lesions when fed a cholesterol-rich diet containing taurocholate. We examined the metabolic basis for the taurocholate requirement.
S Dueland, J Drisko, L Graf, D Machleder, AJ Lusis, RA Davis   +5 more
doaj   +1 more source

Differential Effects on Survival, Humoral Immune Responses and Brain Lesions in Inbred BALB/C, CBA/CA, and C57BL/6 Mice Experimentally Infected withNeospora caninumTachyzoites [PDF]

ISRN Parasitology, 2013
C57BL/6, BALB/c, and CBA/Ca mouse strains with different MHC-I haplotypes were compared with respect to susceptibility toNeospora caninuminfection. Groups of 5 mice received , , or tachyzoites of the NC-Liverpool isolate by intraperitoneal injection and were observed for disease symptoms.
Tanja Mols-Vorstermans, Andrew Hemphill, Thierry Monney, Dick Schaap, Eveline Boerhout   +4 more
openaire   +4 more sources

Adipocyte‐specific ablation of plakoglobin in mice does not affect adiposity but results in sexual‐dimorphic effects on weight gain

Physiological Reports, Volume 13, Issue 24, December 2025.
Abstract The main transcriptional coactivator of the WNT pathway, β‐catenin, is a well‐established regulator of adipogenesis and fat expansion, but our knowledge of how other members of the catenin family participate in adipogenesis remains incomplete. Previous studies have elucidated a role for the β‐catenin homolog, plakoglobin, in the regulation of ...
Frederic Abou Azar, Alexis Vivoli, Arturo I. Machuca‐Parra, Frédéric Paré, Mete Civelek, Weinian Shou, Gareth E. Lim   +6 more
wiley   +1 more source

The effects of levetiracetam and a new 4-phenylpyrrolidone derivative GIZh-290 in a closed cross-maze in BALB/c and C57BL / 6 mice

Фармакокинетика и Фармакодинамика, 2017
The study was aimed to compare the psychopharmacological effects of 2 anticonvulsant drugs levetiracetam ((S)-2-(2-oxopyrrolidin-1-yl) butanamide) and the new compound, GIZh-290 (2-oxo-4-phenylpyrrolidine-1-yl) acetic acid) on behavioral spectra of ...
I. G. Kovalev, E. V. Vasileva, R. O. Bokov, R. M. Salimov, G. I. Kovalev   +4 more
doaj  

Endogenous MMTV proviruses induce susceptibility to both viral and bacterial pathogens.

PLoS Pathogens, 2006
Most inbred mice carry germline proviruses of the retrovirus, mouse mammary tumor virus (MMTV) (called Mtvs), which have multiple replication defects. A BALB/c congenic mouse strain lacking all endogenous Mtvs (Mtv-null) was resistant to MMTV oral and ...
Sanchita Bhadra, Mary M Lozano, Shelley M Payne, Jaquelin P Dudley   +3 more
doaj   +1 more source

Comparison of Metabolomic Profiles of Organs in Mice of Different Strains Based on SPME-LC-HRMS

Metabolites, 2020
Given that the extent to which genetics alters the metabolomic profile of tissues is still poorly understood, the current study aimed to characterize and investigate the metabolite profiles of brain, liver, kidney and skeletal muscle of two common mouse ...
Katarzyna Burlikowska, Iga Stryjak, Joanna Bogusiewicz, Bogumiła Kupcewicz, Karol Jaroch, Barbara Bojko   +5 more
doaj   +1 more source

Biological sex modulates lung injury severity in adolescent mice exposed to short‐term aerosolized vitamin E acetate

Physiological Reports, Volume 13, Issue 23, December 2025.
Abstract The E‐cigarette or Vaping product‐Associated Lung Injury (EVALI) causes severe acute respiratory failure and, in some cases, death. Most cases are linked to tetrahydrocannabinol‐containing e‐cigarette products adulterated with vitamin E acetate.
Michelle J. Lim, Xiaohan Li, Jihau Yu, Heesun Kim, Delaney Stevenson, Negin Esfandiari, Lillian N. Tran, Tran B. Nguyen, Jocelyn A. Livezey, Christoph F. A. Vogel, Eliot R. Spindel, Timothy E. Albertson, Michael A. Matthay, Kent E. Pinkerton   +13 more
wiley   +1 more source

Comparison of the behaviour of three strains of laboratory mice in the climbing test

Animal Welfare, Etológia és Tartástechnológia
In our study, we tested three commonly used strains of laboratory mice in a simple behavioural test. In the climbing test, we looked at the time of the first climb and the number of climbs of the different strains during the 5-minute test time, depending
Henrietta Kinga Török, Boróka Bárdos, Orsolya Ivett Hoffmann   +2 more
doaj   +1 more source

CFTR regulates early pathogenesis of chronic obstructive lung disease in βENaC-overexpressing mice. [PDF]

PLoS ONE, 2012
BACKGROUND: Factors determining the onset and severity of chronic obstructive pulmonary disease remain poorly understood. Previous studies demonstrated that airway surface dehydration in βENaC-overexpressing (βENaC-Tg) mice on a mixed genetic background ...
Bjarki Johannesson, Stephanie Hirtz, Jolanthe Schatterny, Carsten Schultz, Marcus A Mall   +4 more
doaj   +1 more source

Myeloid cell recruitment versus local proliferation differentiates susceptibility from resistance to filarial infection

eLife, 2018
Both TH2-dependent helminth killing and suppression of the TH2 effector response have been attributed to macrophages (MΦ) activated by IL-4 (M(IL-4)). To investigate how M(IL-4) contribute to diverse infection outcomes, the MΦ compartment of susceptible ...
Sharon M Campbell, Johanna A Knipper, Dominik Ruckerl, Conor M Finlay, Nicola Logan, Carlos M Minutti, Matthias Mack, Stephen J Jenkins, Matthew D Taylor, Judith E Allen   +9 more
doaj   +1 more source