Results 101 to 110 of about 54,165 (230)

Thirty Mouse Strain Survey of Voluntary Physical Activity and Energy Expenditure: Influence of Strain, Sex and Day–Night Variation

open access: yesFrontiers in Neuroscience, 2020
We measured indirect calorimetry and activity parameters, VO2 and VCO2 to extract respiratory exchange ratio (RER) and energy expenditure in both sexes of 30 inbred mouse strains of 6 genetic families at 9–13 weeks during one photophase and the ...
Christine König   +6 more
doaj   +1 more source

Upgrading mouse health and welfare: direct benefits of a large-scale rederivation programme [PDF]

open access: yes, 2008
We report the outcome of a 30-month programme to rederive 310 specific pathogen-free mouse strains to populate a new individually ventilated cage barrier facility at the Mary Lyon Centre (MLC), Medical Research Council (MRC) Harwell.
Cheeseman M   +6 more
core   +1 more source

Working with Miraculous Mice: Mus musculus as a Model Organism

open access: yesCurrent Protocols, Volume 4, Issue 10, October 2024.
Abstract The laboratory mouse has been described as a “miracle” model organism, providing a window by which we may gain an understanding of ourselves. Since the first recorded mouse experiment in 1664, the mouse has become the most used animal model in biomedical research.
Anick Standley   +4 more
wiley   +1 more source

OMIP‐105: A 30‐color full‐spectrum flow cytometry panel to characterize the immune cell landscape in spleen and tumor within a syngeneic MC‐38 murine colon carcinoma model

open access: yesCytometry Part A, Volume 105, Issue 9, Page 659-665, September 2024.
Abstract This panel was designed to characterize the immune cell landscape in the mouse tumor microenvironment as well as mouse lymphoid tissues (e.g., spleen). As an example, using the MC‐38 mouse syngeneic tumor model, we demonstrated that we could measure the frequency and characterize the functional status of CD4 T cells, CD8 T cells, regulatory T ...
Gabriel DeNiro   +8 more
wiley   +1 more source

Enhancement of Leishmania amazonensis infection in BCG non-responder mice by BCG-antigen specific vaccine

open access: yesMemorias do Instituto Oswaldo Cruz, 1992
Different patterns of cutaneous leishmaniasis can be induced when a challenge of alike dose of Leishmania amazonensis amastigotes in various inbred strains was applied.
Kátia da Silva Calabrese   +1 more
doaj   +1 more source

Characterization of murine T-cell epitopes on mycobacterial DNA-binding protein 1 (MDP1) using DNA vaccination [PDF]

open access: yes, 2010
Mycobacterial DNA-binding protein 1 (MDP1) is a major protein antigen in mycobacteria and induces protective immunity against Mycobacterium tuberculosis infection in mice.
Koide, Yukio   +5 more
core   +2 more sources

Loss of tolerance to dietary proteins: From mouse models to human model diseases

open access: yesImmunological Reviews, Volume 326, Issue 1, Page 173-190, September 2024.
Summary The critical importance of the immunoregulatory mechanisms, which prevent adverse responses to dietary proteins is demonstrated by the consequences of their failure in two common but distinct human pathological conditions, food allergy and celiac disease.
Anais Levescot, Nadine Cerf‐Bensussan
wiley   +1 more source

Comparison of Adult Hippocampal Neurogenesis and Susceptibility to Treadmill Exercise in Nine Mouse Strains

open access: yesNeural Plasticity, 2017
The genetic background of mice has various influences on the efficacy of physical exercise, as well as adult neurogenesis in the hippocampus. In this study, we investigated the basal level of hippocampal neurogenesis, as well as the effects of treadmill ...
Jong Whi Kim   +7 more
doaj   +1 more source

Quantitative Trait Locus Analysis of Neointimal Formation in an Intercross Between C57BL/6 and C3H/HeJ Apolipoprotein E–Deficient Mice

open access: yesCirculation: Cardiovascular Genetics, 2009
Background—Inbred mouse strains C57BL/6J (B6) and C3H/HeJ (C3H) exhibit marked differences in neointimal formation after arterial injury when deficient in apolipoprotein E (apoE−/−) and fed a Western diet.
Zuobiao Yuan   +6 more
semanticscholar   +1 more source

Mouse genetic approaches applied to the normal tissue radiation response

open access: yesFrontiers in Oncology, 2012
The varying responses of inbred mouse models to radiation exposure present a unique opportunity to dissect the genetic basis of radiation sensitivity and tissue injury.
Christina Kathleen Haston
doaj   +1 more source

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