Results 101 to 110 of about 54,165 (230)
We measured indirect calorimetry and activity parameters, VO2 and VCO2 to extract respiratory exchange ratio (RER) and energy expenditure in both sexes of 30 inbred mouse strains of 6 genetic families at 9–13 weeks during one photophase and the ...
Christine König +6 more
doaj +1 more source
Upgrading mouse health and welfare: direct benefits of a large-scale rederivation programme [PDF]
We report the outcome of a 30-month programme to rederive 310 specific pathogen-free mouse strains to populate a new individually ventilated cage barrier facility at the Mary Lyon Centre (MLC), Medical Research Council (MRC) Harwell.
Cheeseman M +6 more
core +1 more source
Working with Miraculous Mice: Mus musculus as a Model Organism
Abstract The laboratory mouse has been described as a “miracle” model organism, providing a window by which we may gain an understanding of ourselves. Since the first recorded mouse experiment in 1664, the mouse has become the most used animal model in biomedical research.
Anick Standley +4 more
wiley +1 more source
Abstract This panel was designed to characterize the immune cell landscape in the mouse tumor microenvironment as well as mouse lymphoid tissues (e.g., spleen). As an example, using the MC‐38 mouse syngeneic tumor model, we demonstrated that we could measure the frequency and characterize the functional status of CD4 T cells, CD8 T cells, regulatory T ...
Gabriel DeNiro +8 more
wiley +1 more source
Different patterns of cutaneous leishmaniasis can be induced when a challenge of alike dose of Leishmania amazonensis amastigotes in various inbred strains was applied.
Kátia da Silva Calabrese +1 more
doaj +1 more source
Characterization of murine T-cell epitopes on mycobacterial DNA-binding protein 1 (MDP1) using DNA vaccination [PDF]
Mycobacterial DNA-binding protein 1 (MDP1) is a major protein antigen in mycobacteria and induces protective immunity against Mycobacterium tuberculosis infection in mice.
Koide, Yukio +5 more
core +2 more sources
Loss of tolerance to dietary proteins: From mouse models to human model diseases
Summary The critical importance of the immunoregulatory mechanisms, which prevent adverse responses to dietary proteins is demonstrated by the consequences of their failure in two common but distinct human pathological conditions, food allergy and celiac disease.
Anais Levescot, Nadine Cerf‐Bensussan
wiley +1 more source
The genetic background of mice has various influences on the efficacy of physical exercise, as well as adult neurogenesis in the hippocampus. In this study, we investigated the basal level of hippocampal neurogenesis, as well as the effects of treadmill ...
Jong Whi Kim +7 more
doaj +1 more source
Background—Inbred mouse strains C57BL/6J (B6) and C3H/HeJ (C3H) exhibit marked differences in neointimal formation after arterial injury when deficient in apolipoprotein E (apoE−/−) and fed a Western diet.
Zuobiao Yuan +6 more
semanticscholar +1 more source
Mouse genetic approaches applied to the normal tissue radiation response
The varying responses of inbred mouse models to radiation exposure present a unique opportunity to dissect the genetic basis of radiation sensitivity and tissue injury.
Christina Kathleen Haston
doaj +1 more source

