Results 101 to 110 of about 20,210 (217)

Mouse genetic approaches applied to the normal tissue radiation response

Frontiers in Oncology, 2012
The varying responses of inbred mouse models to radiation exposure present a unique opportunity to dissect the genetic basis of radiation sensitivity and tissue injury.
Christina Kathleen Haston
doaj   +1 more source

Comparative Effect of Maitake Pro4x with Chemotherapy Breast Cancer Treatment [PDF]

, 2017
Conventional treatments for breast cancer involve surgery followed by radiation and hormonal therapy and/or chemotherapy. Some of these treatments have toxic side effects.
Aguilera Braico, Diego Máximo, Balogh, Gabriela Andrea, Brie, Belen, Roldán Deamicis, Agustina   +3 more
core   +1 more source

Correlational Analysis for Identifying Genes whose Regulation Contributes to Chronic Neuropathic Pain [PDF]

, 2009
Background Nerve injury-triggered hyperexcitability in primary sensory neurons is considered a major source of chronic neuropathic pain. The hyperexcitability, in turn, is thought to be related to transcriptional switching in afferent cell somata ...
Anna-Karin Persson, Mathias Gebauer, Suzana Jordan, Christiane Metz-Weidmann, Anke M Schulte, Hans-Christoph Schneider, Danping Ding-Pfennigdorff, Jonas Thun, Xiao-Jun Xu, Zsuzsanna Wiesenfeld-Hallin, Ariel Darvasi, Kaj Fried, Marshall Devor, Bonilla IE, Ali Z, Allchorne A, Mogil JS   +16 more
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Identification of novel molecular candidates for fatty liver in the hyperlipidemic mouse model, HcB19

Journal of Lipid Research, 2004
The inbred HcB19 mouse strain expresses a truncated form of thioredoxin interacting protein and is phenotypically characterized by fatty liver and elevated plasma triglycerides and VLDL.
Marleen M.J. van Greevenbroek, Vicky M. M-J. Vermeulen, Tjerk W.A. de Bruin   +2 more
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The development of a mouse model to explore resistance and susceptibility to early Ascaris suum infection [PDF]

, 2005
Ascaris suum and Ascaris lumbricoides exhibit an over-dispersed frequency distribution in their host populations in both the adult and larval stages. The impact of host factors on this observed distribution is still poorly understood and difficult to ...
C. V. HOLLAND, Crompton, Douvres, Eriksen, J. M. BEHNKE, Johnstone, Lee, Loeffler, McSharry, Mitchell, Murrell, Norozian-Amiri, Oksanen, P. STAFFORD, Pemberton, R. LEWIS, Rodriguez-Sosa, Slotved, Sprent, Taffs   +19 more
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Effect of the Y chromosome on plasma high-density lipoprotein-cholesterol levels in Y-chromosome-consomic mouse strains [PDF]

, 2014
BACKGROUND: Plasma high-density lipoprotein (HDL)-cholesterol level is a clinically important quantitative phenotype that widely varies among inbred mouse strains.
Jun-ichi Suto, Kunio Satou
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Variation in genome-wide levels of meiotic recombination is established at the onset of prophase in mammalian males.

PLoS Genetics, 2014
Segregation of chromosomes during the first meiotic division relies on crossovers established during prophase. Although crossovers are strictly regulated so that at least one occurs per chromosome, individual variation in crossover levels is not uncommon.
Brian Baier, Patricia Hunt, Karl W Broman, Terry Hassold   +3 more
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Ventilatory Phenotypes among Four Strains of Adult Rats. [PDF]

, 2002
Our purpose in this study was to identify different ventilatory phenotypes among four different strains of rats. We examined 114 rats from three in-house, inbred strains and one outbred strain: Brown Norway (BN;n = 26), Dahl salt-sensitive (n = 24), Fawn-
Dwinell, Melinda R., Forster, Hubert, Hodges, Matthew, Hogan, Genevieve E., Papanek, Paula   +4 more
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Effect of trehalose on the preservation of freeze-dried mice spermatozoa at room temperature

The Journal of Reproduction and Development, 2019
Freeze-drying of spermatozoa is a convenient and safe method to preserve mammalian genetic material without the use of liquid nitrogen or a deep freezer. However, freeze-dried spermatozoa (FD sperm) are not frequently used because of the low success rate
Daiyu ITO, Sayaka WAKAYAMA, Yuko KAMADA, Ikue SHIBASAKI, Satoshi KAMIMURA, Masatoshi OOGA, Teruhiko WAKAYAMA   +6 more
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Genotype-Dependent Difference in 5-HT2C Receptor-Induced Hypolocomotion: Comparison with 5-HT2A Receptor Functional Activity

Neural Plasticity, 2015
In the present study behavioral effects of the 5-HT2C serotonin receptor were investigated in different mouse strains. The 5-HT2C receptor agonist MK-212 applied intraperitoneally induced significant dose-dependent reduction of distance traveled in the ...
Darya V. Bazovkina, Elena M. Kondaurova, Vladimir S. Naumenko, Evgeni Ponimaskin   +3 more
doaj   +1 more source